Reactome | SRP54 [cytosol]

SRP54 [cytosol]

Stable Identifier

R-HSA-264977

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P61011 SRP54

Gene Names

SRP54

Chain

chain:1-504

Reference Genes

BioGPS Gene:6729 SRP54

COSMIC (genes):SRP54 SRP54

CTD Gene:6729 SRP54

dbSNP Gene:6729 SRP54

ENSEMBL:ENSG00000100883 SRP54

HGNC:11301 SRP54

KEGG:hsa:6729 SRP54

Monarch:6729 SRP54

NCBI Gene:6729 SRP54

OMIM:604857 SRP54

UCSC:P61011 SRP54

Reference Transcript

Other Identifiers

11718114_a_at

11748482_a_at

16783310

203605_PM_at

203605_at

3532314

3532316

3532317

3532318

3532319

3532320

3532321

3532323

3532324

3532325

3532326

3532327

3532328

3532329

3532330

3532331

3532332

3532333

3532334

3532335

3532340

3532341

3532342

3532344

3532345

3532347

3532348

36060_at

3836648

6729

7973902

84475_at

A_14_P106163

A_14_P107389

A_23_P162945

A_33_P3276222

GE59223

GO:0002376

GO:0003723

GO:0003824

GO:0003924

GO:0005515

GO:0005525

GO:0005634

GO:0005737

GO:0005783

GO:0005786

GO:0005829

GO:0006614

GO:0006616

GO:0006617

GO:0006886

GO:0008312

GO:0016607

GO:0016787

GO:0016887

GO:0019003

GO:0030154

GO:0030593

GO:0030851

GO:0030942

GO:0031017

GO:0043021

GO:0043226

GO:0045047

GO:0048500

GO:0048856

GO:0048870

GO:0055085

GO:0065003

HMNXSV003016048

ILMN_1663149

ILMN_1753862

ILMN_2312275

PH_hs_0003438

TC14000219.hg

U51920_at

g4507214_3p_at

Participates

as a component of

Signal Recognition Particle [cytosol] (Homo sapiens)

Inferred To

Srp54k [cytosol] (Drosophila melanogaster)

srp54 [cytosol] (Xenopus tropicalis)

SRP54_CANFA [cytosol] (Canis familiaris)

SRP54 [cytosol] (Bos taurus)

SRP54 [cytosol] (Caenorhabditis elegans)

SRP54 [cytosol] (Danio rerio)

SRP54 [cytosol] (Dictyostelium discoideum)

SRP54 [cytosol] (Gallus gallus)

SRP54 [cytosol] (Mus musculus)

SRP54 [cytosol] (Plasmodium falciparum)

SRP54 [cytosol] (Rattus norvegicus)

SRP54 [cytosol] (Saccharomyces cerevisiae)

SRP54 [cytosol] (Schizosaccharomyces pombe)

SRP54 [cytosol] (Sus scrofa)

Cross References

ENSEMBL

ENST00000556994, ENSP00000504518, ENST00000677647, ENST00000216774, ENSP00000451818, ENSP00000216774, ENSG00000100883, ENST00000678963, ENSP00000504673

OpenTargets

ENSG00000100883

GeneCards

SRP54

HPA

ENSG00000100883-SRP54

PRO

P61011

Pharos - Targets

P61011

GlyGen

P61011

Orphanet

SRP54

HMDB Protein

HMDBP08585

PDB

6Y2Z, 5L3Q, 1QB2, 6Y31, 6Y30, 7QWQ, 1MFQ, 7NFX, 6Y32

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P08240 SRPRA	1	SRPR [endoplasmic reticulum membrane] (R-HSA-264970)	0.558	2
UniProt:P11142 HSPA8	10	HSPA8 [cytosol] (R-HSA-264476) HSPA8 [lysosomal lumen] (R-HSA-9625182) HSPA8 [late endosome lumen] (R-HSA-9631104) HSPA8 [clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane] (R-HSA-888599) HSPA8 [plasma membrane] (R-HSA-936508) HSPA8 [nucleoplasm] (R-HSA-5082380) HSPA8 [ficolin-1-rich granule lumen] (R-HSA-6801494) HSPA8 [extracellular region] (R-HSA-6805936) HSPA8 [secretory granule lumen] (R-HSA-6801530) Me3K561-HSPA8 [nucleoplasm] (R-HSA-8932217)	0.527	2