Cystine-bonded Proinsulin translocates from the endoplasmic reticulum to the Golgi

Stable Identifier
R-HSA-265010
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Proinsulin in the endoplasmic reticulum moves to the Golgi apparatus via vesicles that bud from the endoplasmic reticulum.

Literature References
PubMed ID Title Journal Year
3896518 Direct identification of prohormone conversion site in insulin-secreting cells

Orci, L, Ravazzola, M, Amherdt, M, Madsen, O, Vassalli, JD, Perrelet, A

Cell 1985
9631292 The role of assembly in insulin's biosynthesis

Dodson, G, Steiner, D

Curr Opin Struct Biol 1998
Participants
Participant Of
Orthologous Events
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Reviewed