Reactome | EXOC6 [plasma membrane]

EXOC6 [plasma membrane]

Stable Identifier

R-HSA-265041

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q8TAG9 EXOC6

Gene Names

EXOC6, SEC15A, SEC15L, SEC15L1

Chain

chain:1-804

Reference Genes

BioGPS Gene:54536 EXOC6

COSMIC (genes):EXOC6 EXOC6

CTD Gene:54536 EXOC6

dbSNP Gene:54536 EXOC6

ENSEMBL:ENSG00000138190 EXOC6

HGNC:23196 EXOC6

KEGG Gene (Homo sapiens):54536 EXOC6

Monarch:54536 EXOC6

NCBI Gene:54536 EXOC6

OMIM:609672 EXOC6

UCSC:Q8TAG9 EXOC6

Reference Transcript

Other Identifiers

0002510025

11723221_a_at

11755493_a_at

16707503

226259_at

233924_s_at

3258257

3258261

3258262

3258271

3258283

3258284

3258285

3258286

3258288

3258290

3258292

3258295

3258298

3258301

3258302

3258303

3258304

3258306

3258307

3258308

3258309

3258311

3258318

3258319

3258320

3258328

3258338

3258341

3258342

3258355

3258356

49287_at

54536

59310_at

7929288

A_14_P139287

A_23_P169576

A_32_P58280

GE56714

GO:0000145

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005829

GO:0005886

GO:0006810

GO:0006887

GO:0006893

GO:0006904

GO:0008150

GO:0015031

GO:0016020

GO:0016192

GO:0030426

GO:0032991

GO:0042995

GO:0048471

GO:0090543

Hs.110454.0.S1_3p_at

Hs.110454.1.S1_3p_a_at

ILMN_1651628

ILMN_1667686

ILMN_1679687

PH_hs_0023364

TC10000661.hg

Participant Of

hasComponent

Exocyst Complex [plasma membrane]

input

Exocyst complex formation

Other forms of this molecule

EXOC6 [cytosol]

Inferred To

Sec15 [plasma membrane] (Drosophila melanogaster)

EXOC6 [plasma membrane] (Gallus gallus)

EXOC6 [plasma membrane] (Sus scrofa)

Exoc6 [plasma membrane] (Mus musculus)

Exoc6 [plasma membrane] (Rattus norvegicus)

sec-15 [plasma membrane] (Caenorhabditis elegans)

SEC15 [plasma membrane] (Saccharomyces cerevisiae)

sec15 [plasma membrane] (Schizosaccharomyces pombe)

exoc6 [plasma membrane] (Danio rerio)

exoc6 [plasma membrane] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001306124.1, NP_001013870.1, NP_001306129.1, XP_016871834.1, NP_001306123.1, NP_061926.3

OpenTargets

ENSG00000138190

GeneCards

Q8TAG9

HPA

ENSG00000138190-EXOC6

Ensembl

ENST00000671701, ENSG00000138190, ENSP00000260762, ENST00000260762, ENST00000672817, ENSP00000500468, ENSP00000360607, ENSP00000500529, ENST00000371552

PRO

Q8TAG9

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O00471 EXOC5	2	EXOC5 [cytosol] (R-HSA-5623383) EXOC5 [cytosol] (R-HSA-265045)	0.793	7
UniProt:Q96A65 EXOC4	2	EXOC4 [plasma membrane] (R-HSA-264989) EXOC4 [cytosol] (R-HSA-5623381)	0.725	5
UniProt:Q96KP1 EXOC2	2	EXOC2 [plasma membrane] (R-HSA-264887) EXOC2 [cytosol] (R-HSA-5623376)	0.638	3
UniProt:Q8IYI6 EXOC8	2	EXOC8 [cytosol] (R-HSA-5623388) EXOC8 [plasma membrane] (R-HSA-264948)	0.638	4
UniProt:Q53GS7 GLE1	1	GLE1 [nucleoplasm] (R-HSA-8932905)	0.556	3
UniProt:Q7Z699 SPRED1	2	SPRED1 [cytosol] (R-HSA-5654207) SPRED1 [plasma membrane] (R-HSA-5658225)	0.556	3
UniProt:Q9NV70 EXOC1	2	EXOC1 [cytosol] (R-HSA-5623375) EXOC1 [plasma membrane] (R-HSA-2872284)	0.508	2
UniProt:P61006 RAB8A	6	RAB8A [cytosol] (R-HSA-5623399) RAB8A [Golgi membrane] (R-HSA-2562535) GGC-RAB8A [cytosol] (R-HSA-8874063) GGC-RAB8A [trans-Golgi network membrane] (R-HSA-8876082) RAB8A [recycling endosome membrane] (R-HSA-8854145) GGC-RAB8A [cytoplasmic vesicle membrane] (R-HSA-1445093)	0.508	2
UniProt:O60645 EXOC3	2	EXOC3 [secretory granule membrane] (R-HSA-2872286) EXOC3 [cytosol] (R-HSA-5623379)	0.508	2
UniProt:Q16891 IMMT	1	IMMT (MIC60) [mitochondrial inner membrane] (R-HSA-8949569)	0.508	2
UniProt:Q9UPT5 EXOC7	2	EXOC7 [cytosol] (R-HSA-5623386) EXOC7 [plasma membrane] (R-HSA-2872288)	0.508	3

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