Proinsulin:Zinc:Calcium complex translocates to immature secretory granule

Stable Identifier
R-HSA-265153
Type
Reaction [BlackBoxEvent]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Immature, clathrin-coated vesicles containing proinsulin-zinc-calcium complexes bud from the trans-golgi network.

Literature References
PubMed ID Title Journal Year
3896518 Direct identification of prohormone conversion site in insulin-secreting cells

Orci, L, Ravazzola, M, Amherdt, M, Madsen, O, Vassalli, JD, Perrelet, A

Cell 1985
9631292 The role of assembly in insulin's biosynthesis

Dodson, G, Steiner, D

Curr Opin Struct Biol 1998
Participants
Participant Of
Orthologous Events
Authored
Reviewed