Reactome | Interaction of integrin alphaVbeta3 with von Willbrand Factor

Stable Identifier

R-HSA-265425

Type

Reaction

Species

Homo sapiens

Compartment

extracellular region, plasma membrane

Locations in the PathwayBrowser

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Summation

Integrin alphaVbeta3 interacts with von Willebrand factor (vWF) on the RGD motif (1744-1746 residues) present on the mature vWF subunit.

Literature References

PubMed ID	Title	Journal	Year
7505120	Solid-phase von Willebrand factor contains a conformationally active RGD motif that mediates endothelial cell adhesion through the alpha v beta 3 receptor Denis, C, Williams, JA, Lu, X, Meyer, D, Baruch, D	Blood	1993

Participants

Input

Output

Participant Of

hasEvent

Orthologous Events

Authored

Geiger, B (2008-05-07)

Horwitz, AR (2008-05-07)

Reviewed

Yamada, KM (2008-05-07)

Humphries, MJ (2008-05-07)

Hynes, R (2008-05-07)