LTC4 is exported from the cytosol by ABCC1

Stable Identifier
R-HSA-266070
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
ABCC1 mediates LTC4 export from the cell
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
On formation, leukotriene C4 (LTC4) is exported to the extracellular region by the ABCC1 transporter (Sjolinder et al. 1999, Lam et al. 1989) and processed further by cleavage reactions.
Literature References
PubMed ID Title Journal Year
2753893 The identification of a distinct export step following the biosynthesis of leukotriene C4 by human eosinophils

Soberman, RJ, Owen WF, Jr, Lam, BK, Austen, KF

J Biol Chem 1989
10064732 Characterization of a leukotriene C4 export mechanism in human platelets: possible involvement of multidrug resistance-associated protein 1

Hydman, J, Sjölinder, M, Tornhamre, S, Claesson, HE, Lindgren, J

J Lipid Res 1999
Participants
Participates
Catalyst Activity

ABC-type transporter activity of ABCC1 [plasma membrane]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
Cite Us!