LTC4 is exported from the cytosol by ABCC1

Stable Identifier
R-HSA-266070
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Synonyms
ABCC1 mediates LTC4 export from the cell
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On formation, leukotriene C4 (LTC4) is exported to the extracellular region by the ABCC1 transporter (Sjolinder et al. 1999, Lam et al. 1989) and processed further by cleavage reactions.

Literature References
PubMed ID Title Journal Year
10064732 Characterization of a leukotriene C4 export mechanism in human platelets: possible involvement of multidrug resistance-associated protein 1

Sjölinder, M, Tornhamre, S, Claesson, HE, Hydman, J, Lindgren, J

J Lipid Res 1999
2753893 The identification of a distinct export step following the biosynthesis of leukotriene C4 by human eosinophils

Lam, BK, Owen WF, Jr, Austen, KF, Soberman, RJ

J Biol Chem 1989
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
ATPase activity, coupled to transmembrane movement of substances of ABCC1 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created