Reactome: A Curated Pathway Database

LTA4 is hydolysed to LTB4 by LTA4H

Stable Identifier
R-HSA-266072
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
LTA4 is hydrolyzed to LTB4
Locations in the PathwayBrowser
Summation

Leukotriene A4 hydrolase (LTA4H) is a monomeric, soluble enzyme that catalyzes the hydrolysis of the allylic epoxide leukotriene A4 (LTA4) to the dihydroxy acid leukotriene B4 (LTB4) (Radmark et al. 1984, McGee & Fitzpatrick 1985).

Literature References
Participants
Participant Of
This entity is regulated by:
Title Physical Entity Activity
leukotriene-A4 hydrolase activity of LTA4H:Zn2+ [cytosol] LTA4H:Zn2+ [cytosol] leukotriene-A4 hydrolase activity (0004463)
Orthologous Events
Cross References
Rhea