p-4Y-PLCG2 [plasma membrane]

Stable Identifier
R-HSA-2685601
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
p-Y753,Y759,Y1197,Y1217-PLCG2, PLCG2, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2, PLCG2_HUMAN
Locations in the PathwayBrowser
Literature References
PubMed ID Title Journal Year
15509800 Mechanism of B-cell receptor-induced phosphorylation and activation of phospholipase C-gamma2

Kim, YJ, Sekiya, F, Poulin, B, Bae, YS, Rhee, SG

Mol Cell Biol 2004
External Reference Information
External Reference
Gene Names
PLCG2
Chain
chain:1-1265
Reference Transcript
Other Identifiers
0000360131
1085_s_at
11720244_at
1557993_at
16821330
16821365
204613_at
230917_at
3670950
3670955
3670956
3670973
3670976
3670978
3670985
3670986
3670990
3670991
3670993
3670994
3670996
3670997
3670999
3671000
3671004
3671006
3671007
3671008
3671009
3671011
3671012
3671014
3671016
3671017
3671021
3671026
3671029
3671030
3671034
3671037
3671038
3671039
3671042
3671048
3671049
3671050
3671051
3671052
3671053
3671054
3671055
3671056
3671057
37180_at
5336
7997453
7997489
A_23_P106675
A_32_P52632
GE57955
GE61863
GO:0001784
GO:0002092
GO:0002223
GO:0002316
GO:0002376
GO:0003674
GO:0004435
GO:0004629
GO:0005515
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005623
GO:0005737
GO:0005829
GO:0005886
GO:0006629
GO:0006661
GO:0006810
GO:0006950
GO:0007165
GO:0007267
GO:0008081
GO:0008150
GO:0008219
GO:0009056
GO:0009058
GO:0009395
GO:0010468
GO:0010634
GO:0016042
GO:0016055
GO:0016192
GO:0016787
GO:0019722
GO:0030154
GO:0030168
GO:0030183
GO:0032237
GO:0032481
GO:0032496
GO:0032959
GO:0035556
GO:0038095
GO:0038096
GO:0040011
GO:0042592
GO:0043069
GO:0043226
GO:0043647
GO:0044281
GO:0048015
GO:0048856
GO:0048870
GO:0050852
GO:0050853
GO:0051209
GO:0055085
GO:0070062
Hs.6179.2.A1_3p_at
Hs.6179.2.A1_3p_x_at
Hs2.382891.1.S1_3p_at
Hs2.382891.1.S1_3p_x_at
ILMN_1815719
M37238_s_at
PH_hs_0026742
TC16000643.hg
TC16000644.hg
TC16001663.hg
g4505870_3p_at
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
O4'-phospho-L-tyrosine at 753
Coordinate
753
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 759
Coordinate
759
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1217
Coordinate
1217
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1197
Coordinate
1197
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
OpenTargets
ZINC - Substances
GeneCards
ZINC target
PRO
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
PDB
Interactors (12)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P00533 EGFR  59 0.802 6
 UniProt:P04626 ERBB2  117 0.609 3
 UniProt:P27986 PIK3R1  15 0.589 2
 UniProt:O14796 SH2D1B  1 0.525 2
 UniProt:O95073-2 FSBP      0.508 2
 UniProt:O43242 PSMD3  5 0.508 2
 UniProt:P10809 HSPD1  6 0.488 2
 UniProt:Q99645 EPYC      0.488 2
 UniProt:Q68G74 LHX8      0.488 2
 UniProt:O95997 PTTG1  2 0.488 2
 UniProt:P19419 ELK1  2 0.488 2
 UniProt:P04637 TP53  27 0.488 2
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