Reactome | FXYD3 [plasma membrane]

FXYD3 [plasma membrane]

Stable Identifier

R-HSA-2752084

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

FXYD domain-containing ion transport regulator 3, FXYD3_HUMAN

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - SARS-CoV Infections (Homo sapiens)
    - Potential therapeutics for SARS (Homo sapiens)
      - ATP1A:ATP1B:FXYD binds cardiac glycosides (Homo sapiens)
        
        ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
        
        FXYDs [plasma membrane] (Homo sapiens)
        
        FXYD3 [plasma membrane] (Homo sapiens)
        
        ATP1A:ATP1B:FXYD:cardiac glycosides [plasma membrane] (Homo sapiens)
        
        ATP1A:ATP1B:FXYD [plasma membrane] (Homo sapiens)
        
        FXYDs [plasma membrane] (Homo sapiens)
        
        FXYD3 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q14802 FXYD3

Gene Names

FXYD3, MAT8, PLML

Chain

signal peptide:1-20, chain:21-87

Reference Genes

BioGPS Gene:5349 FXYD3

COSMIC (genes):FXYD3 FXYD3

CTD Gene:5349 FXYD3

dbSNP Gene:5349 FXYD3

ENSEMBL:ENSG00000089356 FXYD3

HGNC:4027 FXYD3

KEGG Gene (Homo sapiens):5349 FXYD3

Monarch:5349 FXYD3

NCBI Gene:5349 FXYD3

OMIM:604996 FXYD3

UCSC:Q14802 FXYD3

Reference Transcript

Other Identifiers

0003520605

0004070735

11733254_a_at

11734193_a_at

11741254_a_at

11741788_at

11754040_a_at

11754041_x_at

16860888

202488_s_at

202489_s_at

3830167

3830168

3830169

3830170

3830171

3830172

3830175

3830176

3830177

3830179

3830181

3830182

3830183

3830184

3830185

3830186

3830187

3830188

39087_at

5349

8027748

A_24_P293192

A_33_P3228450

A_33_P3228455

A_33_P3228460

A_33_P3228466

GE80330

GE87022

GO:0003013

GO:0003674

GO:0005254

GO:0005575

GO:0005576

GO:0005615

GO:0005886

GO:0005887

GO:0006810

GO:0006811

GO:0006813

GO:0006814

GO:0006821

GO:0008150

GO:0016020

GO:0016021

GO:0017080

GO:0022857

GO:0034220

GO:0043226

GO:0043269

GO:0055085

GO:0070062

GO:0099106

GO:1902476

GO:1903779

GO:2000649

ILMN_1665372

ILMN_1791580

PH_hs_0015534

TC19000458.hg

U28249_at

X93036_at

g11612675_3p_a_at

g13528881_3p_a_at

Participant Of

hasMember

FXYDs [plasma membrane]

Inferred To

fxyd2 [plasma membrane] (Danio rerio)

Homologues of FXYD3 [plasma membrane] (Danio rerio)

fxyd1 [plasma membrane] (Danio rerio)

Fxyd3 [plasma membrane] (Mus musculus)

Fxyd3 [plasma membrane] (Rattus norvegicus)

FXYD3 [plasma membrane] (Bos taurus)

FXYD3 [plasma membrane] (Canis familiaris)

FXYD3 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

XP_016882367.1, NP_005962.1, NP_001129482.1, NP_001129484.1, NP_001129480.1, NP_001129483.1, NP_001129481.1, NP_068710.1, XP_005259053.1, NP_001129479.1, XP_016882366.1

OpenTargets

ENSG00000089356

HPA

ENSG00000089356-FXYD3

GeneCards

Q14802

Ensembl

ENSP00000474438, ENSP00000474526, ENSP00000474055, ENSP00000339499, ENST00000603181, ENSP00000389770, ENSP00000474851, ENST00000604404, ENSG00000089356, ENST00000604621, ENSP00000473929, ENST00000435734, ENST00000346446, ENST00000603449, ENSP00000474622, ENST00000605677, ENSP00000328259, ENST00000344013, ENST00000604255, ENSP00000474855, ENST00000605552

PRO

Q14802

HMDB Protein

HMDBP08197

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O43889 CREB3	7	CREB3(1-256) [cytosol] (R-HSA-8874135) CREB3(1-256) [nucleoplasm] (R-HSA-8874190) CREB3(1-291) [Golgi membrane] (R-HSA-8874181) CREB3(257-291) [Golgi membrane] (R-HSA-8874207) CREB3 [Golgi membrane] (R-HSA-8874123) CREB3(292-395) [Golgi membrane] (R-HSA-8874173) CREB3 [endoplasmic reticulum membrane] (R-HSA-8874165)	0.553	2