NOTCH1 PEST domain mutants bind JAG2

Stable Identifier
R-HSA-2768993
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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NOTCH1 PEST domain mutants are expected to bind to JAG2 ligand in an identical fashion to wild-type NOTCH1 (Luo et al. 1997, Shimizu et al. 2000).

Literature References
PubMed ID Title Journal Year
9315665 Isolation and functional analysis of a cDNA for human Jagged2, a gene encoding a ligand for the Notch1 receptor

Luo, B, Aster, JC, Hasserjian, RP, Kuo, F, Sklar, J

Mol Cell Biol 1997
11006133 Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors

Shimizu, K, Chiba, S, Saito, T, Kumano, K, Hirai, H

Biochem Biophys Res Commun 2000
Participants
Participant Of
Normal reaction
Disease
Name Identifier Synonyms
T-cell leukemia 715
cancer 162 malignant tumor, malignant neoplasm, primary cancer
Authored
Reviewed
Created