NICD1 PEST domain mutants translocate from cytosol to nucleus

Stable Identifier
R-HSA-2769015
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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Cytosolic NICD1 PEST domain mutants are expected to translocate to the nucleus in an identical manner to wild-type NICD1.

Literature References
PubMed ID Title Journal Year
9651681 Indirect evidence for Delta-dependent intracellular processing of notch in Drosophila embryos

Lecourtois, M, Schweisguth, F

Curr Biol 1998
9604939 Nuclear access and action of notch in vivo

Struhl, G, Adachi, A

Cell 1998
Participants
Participant Of
Normal reaction
Disease
Name Identifier Synonyms
T-cell leukemia 715
cancer 162 malignant tumor, malignant neoplasm, primary cancer
Authored
Reviewed
Created