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SELE [plasma membrane]
Stable Identifier
R-HSA-2870223
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
E-selectin, ELAM-1, CD62E
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Cell surface interactions at the vascular wall (Homo sapiens)
E-selectin binds E-selectin ligand (Homo sapiens)
2xSELE ligands:SELE [plasma membrane] (Homo sapiens)
SELE [plasma membrane] (Homo sapiens)
SELE [plasma membrane] (Homo sapiens)
P-selectin binds P-selectin ligand (Homo sapiens)
Selectins [plasma membrane] (Homo sapiens)
SELE [plasma membrane] (Homo sapiens)
Selectins:2xSELPG [plasma membrane] (Homo sapiens)
Selectins [plasma membrane] (Homo sapiens)
SELE [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P16581 SELE
Gene Names
SELE, ELAM1
Chain
signal peptide:1-21, chain:22-610
Reference Genes
BioGPS Gene:6401 SELE
COSMIC (genes):SELE SELE
CTD Gene:6401 SELE
dbSNP Gene:6401 SELE
ENSEMBL:ENSG00000007908 SELE
ENSEMBL_homo_sapiens_GENE:ENSG00000007908.16 SELE
HGNC:10718 SELE
KEGG Gene (Homo sapiens):6401 SELE
Monarch:6401 SELE
NCBI Gene:6401 SELE
OMIM:131210 SELE
UCSC:P16581 SELE
Reference Transcript
RefSeq:NM_000450.2 SELE
Other Identifiers
11726316_at
11726317_at
16696251
206211_PM_at
206211_at
2443477
2443478
2443479
2443480
2443481
2443482
2443483
2443486
2443489
2443490
2443491
2443492
2443493
2443494
2443495
2443496
2443499
2443501
2443502
2443503
2443505
265_s_at
6401
7922229
A_23_P97112
A_33_P3421053
GE56057
GO:0002092
GO:0002376
GO:0002523
GO:0002687
GO:0004888
GO:0005515
GO:0005576
GO:0005615
GO:0005856
GO:0005886
GO:0005901
GO:0005905
GO:0006954
GO:0007155
GO:0007157
GO:0007159
GO:0007202
GO:0009897
GO:0016020
GO:0016192
GO:0019722
GO:0023052
GO:0030029
GO:0030246
GO:0030863
GO:0032496
GO:0033691
GO:0034097
GO:0034612
GO:0043226
GO:0043274
GO:0045121
GO:0046872
GO:0048471
GO:0048870
GO:0050727
GO:0050900
GO:0050901
GO:0060089
GO:0070492
GO:0070555
GO:1903238
HMNXSV003006105
ILMN_1739393
ILMN_2193892
M24736_s_at
PH_hs_0004995
TC01003501.hg
g4506870_3p_at
Participates
as a member of
Selectins [plasma membrane] (Homo sapiens)
as a component of
2xSELE ligands:SELE [plasma membrane] (Homo sapiens)
as an input of
E-selectin binds E-selectin ligand (Homo sapiens)
Inferred To
Hasp [plasma membrane]
(Drosophila melanogaster)
Homologues of SELE [plasma membrane]
(Caenorhabditis elegans)
Homologues of SELE [plasma membrane]
(Drosophila melanogaster)
Homologues of SELE [plasma membrane]
(Sus scrofa)
fw [plasma membrane]
(Drosophila melanogaster)
selp [plasma membrane]
(Danio rerio)
selp [plasma membrane]
(Xenopus tropicalis)
cfh-1 [plasma membrane]
(Caenorhabditis elegans)
hig [plasma membrane]
(Drosophila melanogaster)
SELE [plasma membrane]
(Bos taurus)
SELE [plasma membrane]
(Caenorhabditis elegans)
SELE [plasma membrane]
(Canis familiaris)
SELE [plasma membrane]
(Mus musculus)
SELE [plasma membrane]
(Rattus norvegicus)
SELE [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_000441.2
Guide to Pharmacology - Targets
3200
OpenTargets
ENSG00000007908
ZINC - Substances
LYAM2_HUMAN
ZINC target
P16581
PRO
P16581
PDB
1G1T
,
1ESL
,
6EYI
,
6EYK
,
4CSY
,
4C16
,
6EYJ
ZINC - Investigational
LYAM2_HUMAN
GeneCards
P16581
HPA
ENSG00000007908-SELE
Ensembl
ENSP00000331736
,
ENST00000333360
,
ENSG00000007908
Pharos - Targets
P16581
ZINC - Predictions - Purchasable
LYAM2_HUMAN
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O76024 WFS1
3
WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956747)
p-WFS1 [endoplasmic reticulum lumen]
(R-HSA-8956998)
WFS1 [endoplasmic reticulum membrane]
(R-HSA-535474)
0.556
3
UniProt:Q7Z699 SPRED1
2
SPRED1 [plasma membrane]
(R-HSA-5658225)
SPRED1 [cytosol]
(R-HSA-5654207)
0.556
3
UniProt:P54252 ATXN3
2
ATXN3 [nucleoplasm]
(R-HSA-6783285)
ATXN3 [cytosol]
(R-HSA-5625607)
0.556
3
UniProt:Q9P265 DIP2B
0.527
2
UniProt:Q68D91 MBLC2
0.527
2
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