Translation of OCT4 mRNA

Stable Identifier
R-HSA-2889036
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
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Translation of OCT4 mRNA
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The POU5F1 (OCT4) mRNA is translated to yield protein. LIN28 bound to the mRNA appears to enhance translation (Qiu et al. 2009, Lei et al. 2012).

Literature References
PubMed ID Title Journal Year
22210884 Determinants of mRNA recognition and translation regulation by Lin28

Lei, XX, Xu, J, Ma, W, Qiao, C, Newman, MA, Hammond, SM, Huang, Y

Nucleic Acids Res. 2012
19966271 Lin28-mediated post-transcriptional regulation of Oct4 expression in human embryonic stem cells

Qiu, C, Ma, Y, Wang, J, Peng, S, Huang, Y

Nucleic Acids Res 2009
Participants
Input
Output
Participant Of
hasEvent
This event is regulated
Positively by
Authored
May, B  (2012-12-30)
Reviewed
Wang, J  (2014-01-23)
Created
May, B  (2012-12-31)
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