Reactome | TSG101 [endosome membrane]

Stable Identifier

R-HSA-2980549

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Synonyms

Tumor susceptibility gene 101 protein, TS101_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q99816 TSG101

Gene Names

TSG101

Chain

initiator methionine:, chain:2-390

Reference Genes

COSMIC (genes):TSG101 TSG101

dbSNP Gene:7251 TSG101

ENSEMBL:ENSG00000074319 TSG101

Participates

as a component of

Inferred To

tsg101a [endosome membrane] (Danio rerio)

TSG101 [endosome membrane] (Bos taurus)

TSG101 [endosome membrane] (Canis familiaris)

Tsg101 [endosome membrane] (Mus musculus)

Tsg101 [endosome membrane] (Rattus norvegicus)

UEVLD [endosome membrane] (Gallus gallus)

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O14964 HGS	2	HGS [cytosol] (R-HSA-182954) HGS [phagocytic vesicle lumen] (R-HSA-9635660)	0.785	6
UniProt:Q8N0S2 SYCE1	1	SYCE1 [nucleoplasm] (R-HSA-912456)	0.718	6
UniProt:Q96IF1 AJUBA	3	AJUBA [nucleoplasm] (R-HSA-5687935) p-S-AJUBA [cytosol] (R-HSA-2574841) AJUBA [cytosol] (R-HSA-2564698)	0.683	4
UniProt:Q99LI8	1	HGS [cytosol] (R-MMU-182954)	0.683	5
UniProt:Q8WUM4 PDCD6IP	1	PDCD6IP [cytosol] (R-HSA-917717)	0.609	2
UniProt:P46940 IQGAP1	3	IQGAP1 [cytosol] (R-HSA-5626371) IQGAP1 [secretory granule membrane] (R-HSA-6804803) IQGAP1 [plasma membrane] (R-HSA-381681)	0.581	5
UniProt:O95429 BAG4	3	BAG4 [cytosol] (R-HSA-5212670) BAG4(1-126)-p-8Y-FGFR1(208-822) fusion [plasma membrane] (R-HSA-8853156) BAG4(1-126)-FGFR1(208-822) fusion [plasma membrane] (R-HSA-8853157)	0.556	3
UniProt:Q9UBB9 TFIP11	1	TFIP11 [nucleoplasm] (R-HSA-8869310)	0.556	3
UniProt:Q9Y3M2 CBY1	3	CBY1 [nucleoplasm] (R-HSA-3769210) pS20-CBY1 [nucleoplasm] (R-HSA-3769356) pS20-CBY1 [cytosol] (R-HSA-3769354)	0.556	3
UniProt:P62993 GRB2	1	GRB2 [cytosol] (R-HSA-8983328)	0.527	3
UniProt:Q13464 ROCK1	6	ROCK1 [cytosol] (R-HSA-212509) ROCK1(1-1113) [cytosol] (R-HSA-212523) ROCK1(1114-1354) [cytosol] (R-HSA-212524) Activated ROCK1 [cytosol] (R-HSA-4687777) ROCK1 [secretory granule lumen] (R-HSA-6804967) ROCK1 [extracellular region] (R-HSA-6806527)	0.508	4
UniProt:Q9Y5K6 CD2AP	1	CD2AP [cytosol] (R-HSA-373620)	0.499	2

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