SENP1 [nucleoplasm]

Stable Identifier
R-HSA-2984299
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Sentrin-specific protease 1 ecNumber3.4.22.68/ecNumber, SENP1_HUMAN
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
10652325 Differential regulation of sentrinized proteins by a novel sentrin-specific protease

Millas, S, Maul, GG, Yeh, ET, Gong, L

J. Biol. Chem. 2000
16253240 Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1

Lee, SJ, Kim, Y, Sung, KS, Choi, CY, Kim, YO, Kim, YH

FEBS Lett. 2005
14563852 Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1

O'Hare, P, Bailey, D

J. Biol. Chem. 2004
External Reference Information
External Reference
UniProt:Q9P0U3 SENP1
Gene Names
SENP1
Chain
chain:1-644
Reference Genes
BioGPS Gene:29843 SENP1
COSMIC (genes):SENP1 SENP1
CTD Gene:29843 SENP1
dbSNP Gene:29843 SENP1
ENSEMBL:ENSG00000079387 SENP1
HGNC:17927 SENP1
KEGG Gene (Homo sapiens):29843 SENP1
Monarch:29843 SENP1
NCBI Gene:29843 SENP1
OMIM:612157 SENP1
UCSC:Q9P0U3 SENP1
Reference Transcript
Other Identifiers
0006770593
11739940_a_at
11739941_s_at
1552812_a_at
16763853
226619_at
29843
3452969
3452971
3452972
3452973
3452974
3452975
3452977
3452979
3452980
3452991
3452992
3452993
3452994
3452995
3452996
3453000
3453002
3453003
3453004
3453008
3453010
3453011
3453014
3453015
3453016
3453017
64891_at
66230_at
7962760
A_23_P204536
A_24_P167412
A_33_P3304528
GE81939
GO:0003674
GO:0004175
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005635
GO:0005654
GO:0005737
GO:0005925
GO:0006464
GO:0006508
GO:0006919
GO:0007165
GO:0008150
GO:0008219
GO:0008233
GO:0008234
GO:0009058
GO:0016787
GO:0016926
GO:0031965
GO:0034641
GO:0043226
GO:0045944
GO:0070140
GO:0097190
HMNXSV003032392
Hs.66450.0.S2_3p_at
Hs2.66450.1.S1_3p_s_at
ILMN_1709415
ILMN_3242851
PH_hs_0024495
TC12001443.hg
Participates
as a member of
Other forms of this molecule
SENP1 [cytosol]
Inferred To
ULP1 [nucleoplasm] (Saccharomyces cerevisiae)
Ulp1 [nucleoplasm] (Drosophila melanogaster)
si:dkey-21c19.3 [nucleoplasm] (Danio rerio)
ulp1 [nucleoplasm] (Schizosaccharomyces pombe)
Homologues of SENP1 [nucleoplasm] (Danio rerio)
SENP1 [nucleoplasm] (Bos taurus)
SENP1 [nucleoplasm] (Canis familiaris)
SENP1 [nucleoplasm] (Dictyostelium discoideum)
SENP1 [nucleoplasm] (Gallus gallus)
SENP1 [nucleoplasm] (Plasmodium falciparum)
SENP1 [nucleoplasm] (Sus scrofa)
ulp-2 [nucleoplasm] (Caenorhabditis elegans)
Senp1 [nucleoplasm] (Mus musculus)
Senp1 [nucleoplasm] (Rattus norvegicus)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
HPA
ZINC - Substances
GeneCards
ZINC target
Ensembl
PRO
Pharos - Targets
ZINC - Predictions - Purchasable
PDB
Interactors (3)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P63165 SUMO1  20 0.87 12
 UniProt:P61956 SUMO2  5 0.743 6
 UniProt:P46060 RANGAP1  3 0.591 4
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