SENP1 [nucleoplasm]

Stable Identifier
R-HSA-2984299
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Sentrin-specific protease 1 ecNumber3.4.22.68/ecNumber, SENP1_HUMAN
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
16253240 Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1

Kim, YH, Sung, KS, Lee, SJ, Kim, YO, Choi, CY, Kim, Y

FEBS Lett. 2005
14563852 Characterization of the localization and proteolytic activity of the SUMO-specific protease, SENP1

Bailey, D, O'Hare, P

J. Biol. Chem. 2004
10652325 Differential regulation of sentrinized proteins by a novel sentrin-specific protease

Gong, L, Millas, S, Maul, GG, Yeh, ET

J. Biol. Chem. 2000
External Reference Information
External Reference
UniProt:Q9P0U3 SENP1
Gene Names
SENP1
Chain
chain:1-644
Reference Genes
BioGPS Gene:29843 SENP1
COSMIC (genes):SENP1 SENP1
CTD Gene:29843 SENP1
dbSNP Gene:29843 SENP1
ENSEMBL:ENSG00000079387 SENP1
HGNC:17927 SENP1
KEGG Gene (Homo sapiens):29843 SENP1
Monarch:29843 SENP1
NCBI Gene:29843 SENP1
OMIM:612157 SENP1
UCSC:Q9P0U3 SENP1
Reference Transcript
Other Identifiers
0006770593
11739940_a_at
11739941_s_at
11765
1552812_a_at
16763853
226619_at
29843
2CKG
2CKH
2G4D
2IY0
2IY1
2IYC
2IYD
2XPH
2XRE
3452969
3452971
3452972
3452973
3452974
3452975
3452977
3452979
3452980
3452991
3452992
3452993
3452994
3452995
3452996
3453000
3453002
3453003
3453004
3453008
3453010
3453011
3453014
3453015
3453016
3453017
46491
64891_at
66230_at
7962760
A_23_P204536
A_24_P167412
A_33_P3304528
AAF31171
AAH45639
AC074029
AF149770
AK292060
BAF84749
BC045639
CCDS44868
ENSG00000079387
ENSP00000394791
ENSP00000447328
ENSP00000450076
ENST00000448372
ENST00000448372.5
ENST00000549518
ENST00000549518.5
ENST00000549595
ENST00000549595.5
EntrezGene:29843
EntrezGene:SENP1
F8VRZ8
F8W0I8
GE81939
GO:0002376
GO:0003674
GO:0004175
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005635
GO:0005654
GO:0005737
GO:0005925
GO:0006464
GO:0006508
GO:0006919
GO:0007165
GO:0008150
GO:0008219
GO:0008233
GO:0008234
GO:0009056
GO:0009058
GO:0010724
GO:0016787
GO:0016925
GO:0016926
GO:0030154
GO:0031965
GO:0032435
GO:0034641
GO:0042592
GO:0043226
GO:0045944
GO:0048856
GO:0070140
GO:0097190
HGNC:17927
HPA011765
HPA046491
Hs.66450.0.S2_3p_at
Hs2.66450.1.S1_3p_s_at
ILMN_1709415
ILMN_3242851
IPR003653
IPR038765
MIM:612157
NM_001267594
NM_001267595
NP_001254523
NP_001254524
PF02902
PH_hs_0024495
SENP1
SENP1-201
SENP1-204
SENP1-205
TC12001443.hg
UPI000003756B
UPI0000E595D2
XM_006719361
XM_006719362
XM_011538244
XM_011538245
XM_017019229
XM_017019230
XM_017019231
XM_017019232
XM_017019233
XM_017019234
XM_017019235
XM_017019236
XM_017019237
XM_017019238
XM_017019239
XM_017019240
XP_006719424
XP_006719425
XP_011536546
XP_011536547
XP_016874718
XP_016874719
XP_016874720
XP_016874721
XP_016874722
XP_016874723
XP_016874724
XP_016874725
XP_016874726
XP_016874727
XP_016874728
XP_016874729
Participant Of
hasMember
Inferred To
SENP1 [nucleoplasm] (Bos taurus)
SENP1 [nucleoplasm] (Caenorhabditis elegans)
SENP1 [nucleoplasm] (Canis familiaris)
SENP1 [nucleoplasm] (Danio rerio)
SENP1 [nucleoplasm] (Dictyostelium discoideum)
SENP1 [nucleoplasm] (Drosophila melanogaster)
SENP1 [nucleoplasm] (Gallus gallus)
SENP1 [nucleoplasm] (Mus musculus)
SENP1 [nucleoplasm] (Plasmodium falciparum)
SENP1 [nucleoplasm] (Rattus norvegicus)
SENP1 [nucleoplasm] (Saccharomyces cerevisiae)
SENP1 [nucleoplasm] (Schizosaccharomyces pombe)
SENP1 [nucleoplasm] (Sus scrofa)
SENP1 [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
OpenTargets
GeneCards
ZINC - Substances
ZINC target
PRO
ZINC - Predictions - Purchasable
PDB
Interactors (3)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P63165 SUMO1  155 0.865 9
 UniProt:P61956 SUMO2  5 0.728 5
 UniProt:P46060 RANGAP1  3 0.591 4