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monoSUMO1-K-TP53BP1 [nucleoplasm]
Stable Identifier
R-HSA-2997591
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
SUMO1 N-glycyl-lys TP53BP1, Tumor suppressor p53-binding protein 1, TP53B_HUMAN
Icon
Locations in the PathwayBrowser for interactor UniProt:P61086 UBE2K
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
SUMOylation (Homo sapiens)
SUMO E3 ligases SUMOylate target proteins (Homo sapiens)
SUMOylation of transcription factors (Homo sapiens)
PIAS4 SUMOylates TP53BP1 with SUMO1 (Homo sapiens)
monoSUMO1-K-TP53BP1 [nucleoplasm] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
20016603
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
Jackson, SP
,
Polo, S
,
Coates, J
,
Miller, KM
,
Galanty, Y
,
Belotserkovskaya, R
Nature
2009
External Reference Information
External Reference
UniProt:Q12888 TP53BP1
Gene Names
TP53BP1
Chain
chain:1-1972
Reference Genes
BioGPS Gene:7158 TP53BP1
COSMIC (genes):TP53BP1 TP53BP1
CTD Gene:7158 TP53BP1
dbSNP Gene:7158 TP53BP1
ENSEMBL:ENSG00000067369 TP53BP1
ENSEMBL_homo_sapiens_GENE:ENSG00000067369.14 TP53BP1
HGNC:11999 TP53BP1
KEGG Gene (Homo sapiens):7158 TP53BP1
Monarch:7158 TP53BP1
NCBI Gene:7158 TP53BP1
OMIM:605230 TP53BP1
UCSC:Q12888 TP53BP1
Reference Transcript
RefSeq:NM_001141979.1 TP53BP1
RefSeq:NM_005657.2 TP53BP1
RefSeq:NM_001141980.1 TP53BP1
Other Identifiers
11718808_a_at
11735724_a_at
11735725_x_at
1569097_PM_at
1569097_at
1569098_PM_s_at
1569098_s_at
16808109
1711_at
203050_PM_at
203050_at
213266_PM_at
213266_at
3621190
3621191
3621193
3621195
3621196
3621197
3621198
3621200
3621202
3621203
3621206
3621208
3621209
3621212
3621213
3621214
3621218
3621219
3621220
3621222
3621223
3621225
3621227
3621230
3621234
3621235
3621236
3621237
3621238
3621240
3621241
3621242
3621244
3621245
3621246
3621248
3621250
3621251
3621252
3621255
3621256
3621257
3621259
3621260
3621263
40986_s_at
7158
78028_at
7988093
A_23_P88703
A_32_P118978
GE54711
GO:0000077
GO:0000775
GO:0000776
GO:0000781
GO:0002039
GO:0002376
GO:0003677
GO:0003684
GO:0003712
GO:0005515
GO:0005634
GO:0005654
GO:0005657
GO:0005694
GO:0005737
GO:0006281
GO:0006303
GO:0006310
GO:0006325
GO:0006351
GO:0006355
GO:0006974
GO:0016604
GO:0023052
GO:0035064
GO:0035861
GO:0042162
GO:0042393
GO:0043226
GO:0043565
GO:0045830
GO:0045893
GO:0045944
GO:0048856
GO:0051091
GO:0051260
GO:0060090
GO:0061629
GO:0061649
GO:0065003
GO:0071481
GO:0097680
GO:0140110
GO:0140566
GO:1990391
GO:2000042
HMNXSV003044702
HMNXSV003051954
Hs.20621.1.A1_3p_at
Hs2.407233.1.S1_3p_s_at
ILMN_1664440
PH_hs_0025822
TC15001278.hg
TC15002510.hg
U09477_at
g5032188_3p_at
Participates
as an output of
PIAS4 SUMOylates TP53BP1 with SUMO1 (Homo sapiens)
Other forms of this molecule
p-S25,S1778-TP53BP1 [nucleoplasm]
TP53BP1 [nucleoplasm]
Inferred To
TP53BP1 [nucleoplasm]
(Bos taurus)
TP53BP1 [nucleoplasm]
(Sus scrofa)
crb2 [nucleoplasm]
(Schizosaccharomyces pombe)
RAD9 [nucleoplasm]
(Saccharomyces cerevisiae)
tp53bp1 [nucleoplasm]
(Xenopus tropicalis)
Tp53bp1 [nucleoplasm]
(Mus musculus)
Tp53bp1 [nucleoplasm]
(Rattus norvegicus)
monoSUMO1-K-TP53BP1 [nucleoplasm]
(Dictyostelium discoideum)
monoSUMO1-K-TP53BP1 [nucleoplasm]
(Gallus gallus)
hsr-9 [nucleoplasm]
(Caenorhabditis elegans)
Modified Residues
Name
sumoylated lysine (monoSUMO1 [nucleoplasm]) at unknown position
Modification
monoSUMO1 [nucleoplasm]
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
RefSeq
NP_005648.1
,
NP_001135452.1
,
NP_001135451.1
OpenTargets
ENSG00000067369
ZINC - Substances
TP53B_HUMAN
GeneCards
Q12888
HPA
ENSG00000067369-TP53BP1
ZINC target
Q12888
Ensembl
ENST00000382044
,
ENSP00000393497
,
ENSG00000067369
,
ENST00000450115
,
ENSP00000371475
,
ENSP00000263801
,
ENST00000263801
PRO
Q12888
Pharos - Targets
Q12888
ZINC - Predictions - Purchasable
TP53B_HUMAN
PDB
2G3R
,
6MXZ
,
1GZH
,
5ECG
,
6MY0
,
2MWP
,
6MXY
,
3LH0
,
8EOM
,
6IUA
,
6VIP
,
2IG0
,
6RMM
,
8U4U
,
7YQK
,
6VA5
,
5KGF
,
4RG2
,
2LVM
,
5Z78
,
3LGF
,
7LIN
,
6CO2
,
4CRI
,
1KZY
,
8HKW
,
6CO1
,
7LIO
,
6MXX
,
2MWO
,
3LGL
,
6RML
,
5ZCJ
,
8F0W
,
6IU7
,
4X34
,
5J26
,
8SWJ
,
6UPT
,
1XNI
Interactors (63)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P62805 H4C1
17
polySUMO3-HIST1H4 [nucleoplasm]
(R-HSA-4570531)
monoSUMO1-HIST1H4 [nucleoplasm]
(R-HSA-4570518)
4xAcK-HIST1H4A [nucleoplasm]
(R-HSA-427390)
AcK5,12-HIST1H4A [nucleoplasm]
(R-HSA-212078)
AcK13-HIST1H4 [nucleoplasm]
(R-HSA-4568744)
Me2aR4-HIST1H4 [nucleoplasm]
(R-HSA-5229015)
Me2sR4-HIST1H4 [nucleoplasm]
(R-HSA-4754243)
MeR4-HIST1H4 [nucleoplasm]
(R-HSA-4754240)
Me3K21-HIST1H4 [nucleoplasm]
(R-HSA-5651656)
HIST1H4A [extracellular region]
(R-HSA-977569)
AcK17-HIST1H4 [nucleoplasm]
(R-HSA-427469)
AcK6-HIST1H4 [nucleoplasm]
(R-HSA-4568748)
AcK9-HIST1H4 [nucleoplasm]
(R-HSA-4568758)
MeK21-HIST1H4 [nucleoplasm]
(R-HSA-5423110)
AcK-HIST1H4 [nucleoplasm]
(R-HSA-3451124)
Me2K21-HIST1H4 [nucleoplasm]
(R-HSA-5651652)
HIST1H4 [nucleoplasm]
(R-HSA-181902)
0.87
14
UniProt:P04637 TP53
20
Unfolded TP53 [cytosol]
(R-HSA-6813797)
TP53 [cytosol]
(R-HSA-8869337)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
polySUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
TP53 F341C [nucleoplasm]
(R-HSA-9726318)
TP53 G334V [nucleoplasm]
(R-HSA-9726126)
TP53 L330H [nucleoplasm]
(R-HSA-9726124)
TP53 A347T [nucleoplasm]
(R-HSA-9726339)
TP53 R337C [nucleoplasm]
(R-HSA-9726118)
TP53 L344P [nucleoplasm]
(R-HSA-9726075)
TP53 L344R [nucleoplasm]
(R-HSA-9726073)
TP53 R337H [nucleoplasm]
(R-HSA-9726169)
TP53 R337P [nucleoplasm]
(R-HSA-9726168)
TP53 L330P [nucleoplasm]
(R-HSA-9726136)
TP53 L348S [nucleoplasm]
(R-HSA-9726366)
TP53 R337L [nucleoplasm]
(R-HSA-9726163)
TP53 K351E [nucleoplasm]
(R-HSA-9726258)
TP53 F338I [nucleoplasm]
(R-HSA-9726358)
TP53 R342P [nucleoplasm]
(R-HSA-9726101)
TP53 L330R [nucleoplasm]
(R-HSA-9726133)
0.87
8
UniProt:P16104 H2AFX
7
Me2sR4-H2AFX [nucleoplasm]
(R-HSA-5218317)
H2AFX [nucleoplasm]
(R-HSA-56151)
p-Y143-H2AFX [nucleoplasm]
(R-HSA-5683942)
p-S140,Y143-H2AFX [nucleoplasm]
(R-HSA-5683953)
p-S140-H2AFX [nucleoplasm]
(R-HSA-75170)
K63PolyUb-K14,K16,p-S140-H2AFX [nucleoplasm]
(R-HSA-5682847)
H2AFX [extracellular region]
(R-HSA-977583)
0.793
6
UniProt:Q08AM6 VAC14
3
VAC14 [Golgi membrane]
(R-HSA-1806235)
VAC14 [early endosome membrane]
(R-HSA-1806207)
VAC14 [late endosome membrane]
(R-HSA-1806219)
0.718
6
UniProt:P53350 PLK1
4
PLK1 [nucleoplasm]
(R-HSA-156720)
p-T210-PLK1 [cytosol]
(R-HSA-3000318)
p-T210-PLK1 [nucleoplasm]
(R-HSA-3002800)
PLK1 [cytosol]
(R-HSA-164603)
0.718
6
UniProt:Q6NZQ4 Paxip1
2
Paxip1 [nucleoplasm]
(R-MMU-5619398)
Paxip1 [nucleoplasm]
(R-MMU-5619395)
0.708
5
UniProt:P38398 BRCA1
20
polySUMO2,3-BRCA1 [nucleoplasm]
(R-HSA-2997624)
monoSUMO1-K109-BRCA1 [nucleoplasm]
(R-HSA-2997644)
BRCA1 M1411T [nucleoplasm]
(R-HSA-9702140)
BRCA1 M1400V [nucleoplasm]
(R-HSA-9701202)
BRCA1 L1407P [nucleoplasm]
(R-HSA-9702135)
BRCA1 Y777* [nucleoplasm]
(R-HSA-9702765)
BRCA1 S1009* [nucleoplasm]
(R-HSA-9702755)
BRCA1 P724Lfs*12 [nucleoplasm]
(R-HSA-9703778)
BRCA1 S451* [nucleoplasm]
(R-HSA-9702754)
BRCA1 S864* [nucleoplasm]
(R-HSA-9702752)
BRCA1 P897Kfs*5 [nucleoplasm]
(R-HSA-9703782)
BRCA1 N555Kfs*17 [nucleoplasm]
(R-HSA-9703781)
BRCA1 Y1127Sfs*6 [nucleoplasm]
(R-HSA-9703780)
BRCA1 S886Cfs*16 [nucleoplasm]
(R-HSA-9703802)
BRCA1 V83Cfs*2 [nucleoplasm]
(R-HSA-9703800)
BRCA1 T464Pfs*11 [nucleoplasm]
(R-HSA-9703807)
BRCA1 G813Dfs*2 [nucleoplasm]
(R-HSA-9703549)
BRCA1 V340Gfs*6 [nucleoplasm]
(R-HSA-9703804)
BRCA1 Y655* [nucleoplasm]
(R-HSA-9702769)
BRCA1 W372* [nucleoplasm]
(R-HSA-9702768)
0.7
5
UniProt:P0C0S8 H2AC11
11
K63polyUb-HIST1H2AG [nucleoplasm]
(R-HSA-6783237)
Ub-HIST1H2AG [nucleoplasm]
(R-HSA-6782508)
Ack6-HIST1H2AG [nucleoplasm]
(R-HSA-4568595)
Me2aR30-HIST1H2AG [nucleoplasm]
(R-HSA-5244582)
MeR30-HIST1H2AG [nucleoplasm]
(R-HSA-5244560)
Me2aR4-HIST1H2AG [nucleoplasm]
(R-HSA-5244587)
MeR4-HIST1H2AG [nucleoplasm]
(R-HSA-5244623)
Me2aR12-HIST1H2AG [nucleoplasm]
(R-HSA-5229305)
MeR12-HIST1H2AG [nucleoplasm]
(R-HSA-5229206)
HIST1H2AG [nucleoplasm]
(R-HSA-212084)
Ack-HIST1H2AG [nucleoplasm]
(R-HSA-4551311)
0.672
21
UniProt:Q6ZW49 PAXIP1
1
PAXIP1 [nucleoplasm]
(R-HSA-5619395)
0.656
5
UniProt:P68431 HIST1H3G
20
2xAcK-HIST1H3A [nucleoplasm]
(R-HSA-427507)
Me1K5-H3C1 [nucleoplasm]
(R-HSA-9677683)
Ack-Me3K5-HIST1H3A [nucleoplasm]
(R-HSA-4551293)
AcK-Me3K10-HIST1H3A [nucleoplasm]
(R-HSA-4551291)
AcK-Me3K28-HIST1H3A [nucleoplasm]
(R-HSA-4551292)
Me2aR27-HIST1H3A [nucleoplasm]
(R-HSA-5229052)
Me2aR18-HIST1H3A [nucleoplasm]
(R-HSA-5229062)
Me2sR9-HIST1H3A [nucleoplasm]
(R-HSA-5211328)
Me2sR3-HIST1H3A [nucleoplasm]
(R-HSA-5218935)
AcK9,14-p-S10-HIST1H3A [nucleoplasm]
(R-HSA-8870893)
AcK14,18,79-p-S10-HIST1H3A [nucleoplasm]
(R-HSA-8871271)
AcK9,14,18-p-S10,T11-HIST1H3A [nucleoplasm]
(R-HSA-8871306)
AcK14,18-p-S10,T11-HIST1H3A [nucleoplasm]
(R-HSA-8871294)
AcK9,14,18,79-p-S10,T11-HIST1H3A [nucleoplasm]
(R-HSA-8865596)
AcK14,18-p-S10-HIST1H3A [nucleoplasm]
(R-HSA-8871295)
AcK14,18,79-p-T11-HIST1H3A [nucleoplasm]
(R-HSA-8871288)
AcK14,18-p-T11-HIST1H3A [nucleoplasm]
(R-HSA-8871299)
AcK14,18,79-p-S10,T11-HIST1H3A [nucleoplasm]
(R-HSA-8871286)
Me2K28-HIST1H3A [nucleoplasm]
(R-HSA-4754193)
MeK37-HIST1H3A [nucleoplasm]
(R-HSA-4722135)
0.655
5
UniProt:P63167 DYNLL1
6
DYNLL1 [ciliary tip]
(R-HSA-5625335)
DYNLL1 [cilium]
(R-HSA-5624863)
DYNLL1 [ficolin-1-rich granule membrane]
(R-HSA-6801518)
DYNLL1 [tertiary granule membrane]
(R-HSA-6801482)
DYNLL1 [plasma membrane]
(R-HSA-54017)
DYNLL1 [cytosol]
(R-HSA-387105)
0.643
3
UniProt:Q99986 VRK1
2
VRK1 [nucleoplasm]
(R-HSA-2528998)
VRK1 [cytosol]
(R-HSA-2995381)
0.602
8
UniProt:Q13315 ATM
5
Ac-K3016-ATM [nucleoplasm]
(R-HSA-5682043)
ATM [nucleoplasm]
(R-HSA-69484)
p-S1981,Ac-K3016-ATM [nucleoplasm]
(R-HSA-5693527)
ATM [peroxisomal matrix]
(R-HSA-9665169)
ATM [cytosol]
(R-HSA-9665171)
0.571
2
UniProt:Q7Z699 SPRED1
2
SPRED1 [plasma membrane]
(R-HSA-5658225)
SPRED1 [cytosol]
(R-HSA-5654207)
0.556
3
UniProt:P23763-3 VAMP1
0.556
3
UniProt:P50570-2 DNM2
0.556
3
UniProt:Q5SWW7 CJ055
0.556
3
UniProt:A0A6Q8PF08 A0A6Q8PF08
0.556
3
IntAct:EBI-25857482 CCSB
0.556
3
UniProt:P62826 RAN
2
RAN [nucleoplasm]
(R-HSA-165528)
RAN [cytosol]
(R-HSA-165540)
0.556
3
UniProt:Q13393 PLD1
4
PLD1 [endoplasmic reticulum membrane]
(R-HSA-1498795)
PLD1 [plasma membrane]
(R-HSA-2028998)
PLD1 [tertiary granule membrane]
(R-HSA-6800955)
PLD1 [specific granule membrane]
(R-HSA-6799531)
0.556
3
UniProt:Q02930-3 CREB5
0.556
3
UniProt:P61086 UBE2K
2
UBE2K [cytosol]
(R-HSA-934631)
Ub-C92-UBE2K [cytosol]
(R-HSA-8864200)
0.556
3
UniProt:P46379-2 BAG6
0.556
3
UniProt:Q5T6F2 UBAP2
0.556
3
UniProt:P55212 CASP6
5
CASP6 (1-293) [cytosol]
(R-HSA-6798132)
CASP6(194-293) [nucleoplasm]
(R-HSA-352246)
CASP6(24-179) [nucleoplasm]
(R-HSA-352247)
CASP6(24-179) [cytosol]
(R-HSA-350313)
CASP6(194-293) [cytosol]
(R-HSA-266128)
0.556
3
UniProt:O14645 IDLC
0.556
3
UniProt:P16284 PECAM1
5
PECAM1 [platelet alpha granule membrane]
(R-HSA-61489)
PECAM1 [plasma membrane]
(R-HSA-114686)
PECAM1 [secretory granule membrane]
(R-HSA-6804778)
p-Y663,Y686-PECAM1(27-?) [plasma membrane]
(R-HSA-210007)
p-Y713-PECAM1 [plasma membrane]
(R-HSA-9860772)
0.556
3
IntAct:EBI-25847655 CCSB
0.556
3
UniProt:O75400-2 PRPF40A
0.556
3
UniProt:P13637 ATP1A3
1
ATP1A3 [plasma membrane]
(R-HSA-936803)
0.556
3
UniProt:P41182 BCL6
1
BCL6 [nucleoplasm]
(R-HSA-5223066)
0.556
3
UniProt:P10809 HSPD1
6
HSPD1 [mitochondrial matrix]
(R-HSA-1299448)
HSPD1(1-573) [cytosol]
(R-HSA-1267989)
HSPD1(1-573) [mitochondrial intermembrane space]
(R-HSA-1267963)
HSPD1 [mitochondrial inner membrane]
(R-HSA-1299455)
HSPD1(1-573) [mitochondrial inner membrane]
(R-HSA-1299442)
HSPD1(1-26) [mitochondrial matrix]
(R-HSA-8986171)
0.556
3
UniProt:Q49AR9 Q49AR9
0.556
3
UniProt:P78424 PO6F2
0.556
3
UniProt:Q96G42 KLD7B
0.556
3
UniProt:O43711 TLX3
0.556
3
UniProt:P13473-2 P134732
0.556
3
UniProt:Q96HB5 CC120
0.556
3
UniProt:P04275-2 P042752
0.556
3
UniProt:Q8TDS5 OXER1
1
OXER1 [plasma membrane]
(R-HSA-416425)
0.556
3
UniProt:G5E9A7 G5E9A7
0.556
3
UniProt:P78337 PITX1
0.556
3
UniProt:P50222 MEOX2
0.556
3
UniProt:O14901 KLF11
0.556
3
UniProt:O75190-2 DNAJB6
0.556
3
UniProt:O14964 HGS
2
HGS [cytosol]
(R-HSA-182954)
HGS [phagocytic vesicle lumen]
(R-HSA-9635660)
0.556
3
UniProt:P08670 VIM
11
VIM(2-85) [cytosol]
(R-HSA-350264)
VIM(86-466) [cytosol]
(R-HSA-350294)
VIM(430-466) [cytosol]
(R-HSA-350316)
VIM(2-429) [cytosol]
(R-HSA-350317)
VIM(260-466) [cytosol]
(R-HSA-350314)
VIM(2-259) [cytosol]
(R-HSA-350323)
VIM [cytosol]
(R-HSA-201600)
Vimentin [late endosome lumen]
(R-HSA-9660019)
Vimentin [microtubule organizing center]
(R-HSA-9657898)
Vimentin [cytosol]
(R-HSA-9646687)
Vimentin [lysosomal lumen]
(R-HSA-9659977)
0.556
3
UniProt:Q14676 MDC1
6
monoSUMO1-K1840-MDC1 [nucleoplasm]
(R-HSA-4570546)
polySUMO2,3-K1840-MDC1 [nucleoplasm]
(R-HSA-4570473)
K48PolyUb,SUMO2-K1840,p-5T-MDC1 [nucleoplasm]
(R-HSA-5684074)
SUMO2-K1840,p-5T-MDC1 [nucleoplasm]
(R-HSA-5684061)
p-5T-MDC1 [nucleoplasm]
(R-HSA-75236)
MDC1 [nucleoplasm]
(R-HSA-75231)
0.548
4
UniProt:P62807 H2BC4
9
Ub-HIST1H2BC [nucleoplasm]
(R-HSA-6782552)
AcK-HIST1H2BC [nucleoplasm]
(R-HSA-4549246)
HIST1H2BC [extracellular region]
(R-HSA-977564)
AcK16-HIST1H2BC [nucleoplasm]
(R-HSA-4568634)
AcK6-HIST1H2BC [nucleoplasm]
(R-HSA-4568623)
AcK13-HIST1H2BC [nucleoplasm]
(R-HSA-4568620)
AcK21-HIST1H2BC [nucleoplasm]
(R-HSA-4568626)
Ub-121-HIST1H2BC [nucleoplasm]
(R-HSA-3364029)
HIST1H2BC [nucleoplasm]
(R-HSA-181906)
0.544
6
UniProt:P63165 SUMO1
11
lysyl-G97-SUMO1 [plasma membrane]
(R-HSA-9762382)
lysyl-G97-SUMO1 [nucleolus]
(R-HSA-9762385)
lysyl-G97-SUMO1 [viral capsid]
(R-HSA-9762386)
UBE2I-G97-SUMO1 [cytosol]
(R-HSA-4656941)
lysyl-G97-SUMO1 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-9762380)
lysyl-G97-SUMO1 [cytosol]
(R-HSA-9762266)
UBE2I-G97-SUMO1 [nucleoplasm]
(R-HSA-3730622)
UBA2-G97-SUMO1 [nucleoplasm]
(R-HSA-3730616)
SUMO1 [nucleoplasm]
(R-HSA-877304)
SUMO1(2-101) [nucleoplasm]
(R-HSA-2990831)
lysyl-G97-SUMO1 [nucleoplasm]
(R-HSA-9761562)
0.536
2
UniProt:P01106 MYC
2
PolyUb-MYC [nucleoplasm]
(R-HSA-6783169)
MYC [nucleoplasm]
(R-HSA-188379)
0.536
2
UniProt:Q9UBL3 ASH2L
1
ASH2L [nucleoplasm]
(R-HSA-1629834)
0.536
2
UniProt:Q96FJ2 DYNLL2
4
DYNLL2 [cytosol]
(R-HSA-2029024)
DYNLL2 [plasma membrane]
(R-HSA-140527)
DYNLL2 [cilium]
(R-HSA-5624865)
DYNLL2 [ciliary tip]
(R-HSA-5625337)
0.527
2
UniProt:O43257 ZNHI1
0.524
2
UniProt:Q9UMN6 KMT2B
5
KMT2B [cytosol]
(R-HSA-9818624)
KMT2B(2-2062) [cytosol]
(R-HSA-9818621)
KMT2B(2063-2715) [cytosol]
(R-HSA-9818626)
KMT2B(2063-2715) [nucleoplasm]
(R-HSA-9818623)
KMT2B(2-2062) [nucleoplasm]
(R-HSA-9818620)
0.524
2
UniProt:Q8NAV1 PRPF38A
1
PRPF38A [nucleoplasm]
(R-HSA-8867897)
0.508
2
UniProt:Q86V20-2 SHLD2
0.499
3
UniProt:Q14686 NCOA6
1
NCOA6 [nucleoplasm]
(R-HSA-376414)
0.499
3
UniProt:Q96SB8 SMC6
1
SMC6 [nucleoplasm]
(R-HSA-2993777)
0.483
2
UniProt:Q96RU2 USP28
1
USP28 [nucleoplasm]
(R-HSA-3215039)
0.483
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
7
UniProt:Q71F56 MED13L
1
MED13L [nucleoplasm]
(R-HSA-556797)
0.483
2
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