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Non-integrin membrane-ECM interactions
Stable Identifier
R-HSA-3000171
DOI
10.3180/REACT_163874.1
Type
Pathway
Species
Homo sapiens
ReviewStatus
5/5
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Extracellular matrix organization (Homo sapiens)
Non-integrin membrane-ECM interactions (Homo sapiens)
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Several non-integrin membrane proteins interact with extracellular matrix proteins. Transmembrane proteoglycans may associate with integrins and growth factor receptors to influence their function, or they can signal independently, often influencing the actin cytoskeleton.
Literature References
PubMed ID
Title
Journal
Year
20565253
Transmembrane signaling proteoglycans
Couchman, JR
Annu. Rev. Cell Dev. Biol.
2010
15039999
From cell-ECM interactions to tissue engineering
Barbarisi, A
,
Barbarisi, M
,
Rosso, F
,
Giordano, A
J. Cell. Physiol.
2004
Participants
Events
HSPG2 binds FGF2(10-155), Fibronectn matrix, Transthyretin tetramer, PDGFA homodimer, PDGFB homodimer
(Homo sapiens)
Dystroglycan binds Laminins and Dystrophin
(Homo sapiens)
Dystroglycan binds AGRN and HSPG2
(Homo sapiens)
Dystroglycan binds NRXN1
(Homo sapiens)
NTN4 binds laminins with gamma-1, gamma-3
(Homo sapiens)
DDR1 binds collagen type I, II, III, IV, V, XI fibrils
(Homo sapiens)
DDR2 binds collagen type I, II, III, V, X fibrils
(Homo sapiens)
Syndecan interactions
(Homo sapiens)
Participates
as an event of
Extracellular matrix organization (Homo sapiens)
Event Information
Go Biological Process
extracellular matrix organization (0030198)
Orthologous Events
Non-integrin membrane-ECM interactions (Bos taurus)
Non-integrin membrane-ECM interactions (Caenorhabditis elegans)
Non-integrin membrane-ECM interactions (Canis familiaris)
Non-integrin membrane-ECM interactions (Danio rerio)
Non-integrin membrane-ECM interactions (Drosophila melanogaster)
Non-integrin membrane-ECM interactions (Gallus gallus)
Non-integrin membrane-ECM interactions (Mus musculus)
Non-integrin membrane-ECM interactions (Rattus norvegicus)
Non-integrin membrane-ECM interactions (Sus scrofa)
Non-integrin membrane-ECM interactions (Xenopus tropicalis)
Authored
Jupe, S (2012-07-31)
Reviewed
Ricard-Blum, S (2013-05-22)
Created
Jupe, S (2013-01-24)
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