SUMO3-K65,K160,K490-PML [nucleoplasm]

Stable Identifier
R-HSA-3000386
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
SUMO3 N-glycyl-lys65,160,490 PML, Protein PML, PML_HUMAN
Locations in the PathwayBrowser
General

Fu et al. (2005) report that only lysine-160 is conjugated to SUMO3. Gong and Yeh (2006) report that lysine-65, lysine-160, and lysine-490 are conjugated to SUMO3.

Literature References
PubMed ID Title Journal Year
15940266 Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3

Fu, C, Ahmed, K, Ding, H, Ding, X, Lan, J, Yang, Z, Miao, Y, Zhu, Y, Shi, Y, Zhu, J, Huang, H, Yao, X

Oncogene 2005
16608850 Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3

Gong, L, Yeh, ET

J. Biol. Chem. 2006
External Reference Information
External Reference
Gene Names
PML, MYL, PP8675, RNF71, TRIM19
Chain
chain:1-882
Other Identifiers
0000510706
0004200017
11726875_a_at
11726876_a_at
11728557_s_at
11729443_a_at
11741878_a_at
11741879_x_at
11745905_a_at
11751121_a_at
11751251_a_at
16802918
16802939
206503_x_at
210362_x_at
211012_s_at
211013_x_at
211014_s_at
211588_s_at
239582_at
3601388
3601389
3601390
3601393
3601394
3601395
3601401
3601403
3601410
3601412
3601413
3601414
3601415
3601416
3601417
3601418
3601419
3601420
3601421
3601422
3601423
3601424
3601425
3601426
3601427
3601428
3601436
3601437
3601438
3601439
3601441
3601442
3601443
3601445
3601447
3601449
3601450
3601451
38787_at
38788_at
5371
566_at
567_s_at
7984779
A_14_P130961
A_21_P0008833
A_23_P306148
A_23_P334664
A_23_P358944
A_24_P133542
A_24_P198598
A_24_P207139
GE515151
GE58085
GO:0000228
GO:0000278
GO:0000784
GO:0000785
GO:0000792
GO:0001666
GO:0001932
GO:0002376
GO:0003674
GO:0003677
GO:0004842
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0005737
GO:0005768
GO:0005783
GO:0005789
GO:0005829
GO:0006259
GO:0006355
GO:0006464
GO:0006606
GO:0006810
GO:0006913
GO:0006915
GO:0006919
GO:0006950
GO:0006977
GO:0007049
GO:0007050
GO:0007155
GO:0007165
GO:0007179
GO:0007182
GO:0007568
GO:0007569
GO:0008150
GO:0008219
GO:0008270
GO:0008283
GO:0008285
GO:0008630
GO:0008631
GO:0009056
GO:0009058
GO:0009411
GO:0010332
GO:0010522
GO:0010761
GO:0015031
GO:0016020
GO:0016032
GO:0016363
GO:0016525
GO:0016567
GO:0016605
GO:0019899
GO:0022607
GO:0030099
GO:0030154
GO:0030155
GO:0030308
GO:0030578
GO:0031410
GO:0031625
GO:0031901
GO:0032182
GO:0032183
GO:0032206
GO:0032469
GO:0032691
GO:0032692
GO:0032922
GO:0034097
GO:0034641
GO:0040007
GO:0040011
GO:0042406
GO:0042592
GO:0042752
GO:0042771
GO:0042803
GO:0043153
GO:0043161
GO:0043167
GO:0043226
GO:0044403
GO:0045087
GO:0045165
GO:0045892
GO:0045893
GO:0046332
GO:0046872
GO:0048146
GO:0048384
GO:0048511
GO:0048646
GO:0048856
GO:0048870
GO:0051276
GO:0051457
GO:0051607
GO:0060333
GO:0060444
GO:0065003
GO:0070059
GO:0071353
GO:0072332
GO:0090398
GO:0097191
GO:0140037
GO:1901796
GO:1902187
GO:1990830
GO:2000059
GO:2000779
GO:2001235
GO:2001238
Hs.258217.0.A1_3p_at
ILMN_1696798
ILMN_1731299
ILMN_1750861
ILMN_1811588
ILMN_1812884
ILMN_2248192
ILMN_2398378
M79462_at
M79463_s_at
PH_hs_0005007
TC15000671.hg
TC15002275.hg
TC15002276.hg
X63131_s_at
g12275906_3p_s_at
g12275908_3p_s_at
g190116_3p_at
g4505902_3p_a_at
Participant Of
Other forms of this molecule
Inferred To
Modified Residues
Name
sumoylated lysine (polySUMO3 [nucleoplasm]) at 65
Coordinate
65
Modification
polySUMO3 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (polySUMO3 [nucleoplasm]) at 160
Coordinate
160
Modification
polySUMO3 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Name
sumoylated lysine (polySUMO3 [nucleoplasm]) at 490
Coordinate
490
Modification
polySUMO3 [nucleoplasm]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Interactors (19)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P63165 SUMO1  155 0.832 6
 UniProt:Q9UER7 DAXX  2 0.791 6
 UniProt:Q9Y2M5 KLHL20  1 0.744 9
 UniProt:P04637 TP53  27 0.721 4
 UniProt:P03243-1      0.621 3
 UniProt:Q05516 ZBTB16  1 0.611 7
 UniProt:Q00987 MDM2  11 0.609 6
 UniProt:Q13164 MAPK7  4 0.571 6
 UniProt:Q15583 TGIF1  1 0.556 3
 UniProt:Q8UN00 Q8UN00      0.556 4
 UniProt:P25445 FAS  1 0.524 4
 UniProt:P25788 PSMA3  2 0.508 2
 UniProt:P21359 NF1  37 0.499 2
 UniProt:P03255-1      0.463 2
 UniProt:Q8N9N5 BANP  1 0.463 3
 UniProt:O15169 AXIN1  11 0.463 2
 UniProt:P27958-PRO_0000037566      0.463 6
 UniProt:O14746 TERT  1 0.463 2
 UniProt:O15055 PER2  4 0.463 3
Cite Us!