SUMO1-K524-RANGAP1 [nuclear envelope]

Stable Identifier
R-HSA-3000416
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nuclear envelope
Synonyms
SUMO1 N-glycyl-lys524 RANGAP1, Ran GTPase-activating protein 1, RAGP1_HUMAN
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
11853669 Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1

Bernier-Villamor, V, Sampson, DA, Matunis, MJ, Lima, CD

Cell 2002
19721078 "ChopNSpice," a mass spectrometric approach that allows identification of endogenous small ubiquitin-like modifier-conjugated peptides

Hsiao, HH, Meulmeester, E, Frank, BT, Melchior, F, Urlaub, H

Mol. Cell Proteomics 2009
External Reference Information
External Reference
UniProt:P46060 RANGAP1
Gene Names
RANGAP1, KIAA1835, SD
Chain
initiator methionine:1, chain:2-587
Reference Genes
BioGPS Gene:5905 RANGAP1
COSMIC (genes):RANGAP1 RANGAP1
CTD Gene:5905 RANGAP1
dbSNP Gene:5905 RANGAP1
ENSEMBL:ENSG00000100401 RANGAP1
HGNC:9854 RANGAP1
KEGG Gene (Homo sapiens):5905 RANGAP1
Monarch:5905 RANGAP1
NCBI Gene:5905 RANGAP1
OMIM:602362 RANGAP1
UCSC:P46060 RANGAP1
Reference Transcript
Other Identifiers
0005340739
11717164_a_at
11717165_a_at
1553535_a_at
16935396
1Z5S
212125_at
212127_at
2GRN
2GRO
2GRP
2GRQ
2GRR
2IO2
2IO3
2IY0
32151_at
3961844
3961845
3961846
3961847
3961848
3961851
3961852
3961855
3961857
3961858
3961859
3961860
3961862
3961864
3961865
3961869
3961872
3961873
3961874
3961876
3961877
3961878
3961879
3961880
3961881
3961883
3961885
3961886
3961887
3961888
3961889
3UIN
3UIO
3UIP
4293
50110
5905
5D2M
62034
8076307
A0A024R1U0
A_23_P333420
A_33_P3263307
AAH14044
AAH41396
AB058738
AL035681
B0QYT4
B0QYT5
B0QYT6
BAB47464
BC014044
BC041396
CAA57714
CAB004293
CAG30443
CCDS14012
CH471095
CR456557
EAW60423
EAW60424
ENSG00000100401
ENSP00000348577
ENSP00000385866
ENSP00000401470
ENST00000356244
ENST00000356244.7
ENST00000405486
ENST00000405486.5
ENST00000455915
ENST00000455915.6
EntrezGene:5905
EntrezGene:RANGAP1
GE62508
GO:0000775
GO:0000776
GO:0000777
GO:0003674
GO:0003723
GO:0005096
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005635
GO:0005643
GO:0005654
GO:0005694
GO:0005737
GO:0005819
GO:0005829
GO:0005856
GO:0006464
GO:0006810
GO:0006913
GO:0006950
GO:0007165
GO:0008150
GO:0008536
GO:0015031
GO:0016235
GO:0016925
GO:0019899
GO:0030234
GO:0030425
GO:0031625
GO:0031965
GO:0032991
GO:0043226
GO:0043231
GO:0043547
GO:0044614
GO:0045296
GO:0046826
GO:0048471
GO:0048678
GO:0071375
GO:0072686
GO:0090630
GO:1904115
GO:1904117
GO:1990723
HGNC:9854
HPA050110
HPA062034
Hs.183800.0.S1_3p_at
Hs.183800.0.S2_3p_at
Hs2.183800.1.S1_3p_s_at
ILMN_1662198
IPR001611
IPR009109
IPR032675
IPR036720
MIM:602362
NM_001278651
NM_001317930
NM_002883
NP_001265580
NP_001304859
NP_002874
PF07834
PF13516
PH_hs_0029369
RANGAP1
RANGAP1-201
RANGAP1-202
RANGAP1-207
SM00368
TC22000823.hg
UPI0000000DD9
X82260
XM_005261695
XM_005261696
XM_006724289
XM_011530293
XM_011530294
XM_011530295
XM_017028893
XM_017028894
XM_017028895
XM_017028896
XM_017028897
XM_017028898
XM_017028899
XP_005261752
XP_005261753
XP_006724352
XP_011528595
XP_011528596
XP_011528597
XP_016884382
XP_016884383
XP_016884384
XP_016884385
XP_016884386
XP_016884387
XP_016884388
XR_002958711
Participant Of
hasComponent
Other forms of this molecule
RANGAP1 [nuclear envelope]
RANGAP1 [cytosol]
Inferred To
SUMO1-K524-RANGAP1 [nuclear envelope] (Canis familiaris)
SUMO1-K524-RANGAP1 [nuclear envelope] (Danio rerio)
SUMO1-K524-RANGAP1 [nuclear envelope] (Drosophila melanogaster)
SUMO1-K524-RANGAP1 [nuclear envelope] (Mus musculus)
SUMO1-K524-RANGAP1 [nuclear envelope] (Rattus norvegicus)
SUMO1-K524-RANGAP1 [nuclear envelope] (Sus scrofa)
SUMO1-K524-RANGAP1 [nuclear envelope] (Xenopus tropicalis)
Modified Residues
Name
Inter-chain Crosslink via sumoylated lysine at 524 and 97
Coordinate
524
PsiMod Name
sumoylated lysine
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.
Cross References
RefSeq
OpenTargets
GeneCards
PRO
Orphanet
PDB
Interactors (8)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P63165 SUMO1  155 0.957 13
 UniProt:P63279 UBE2I  8 0.938 10
 UniProt:P61956 SUMO2  5 0.656 4
 UniProt:Q9P0U3 SENP1  1 0.591 4
 UniProt:Q9HC62 SENP2  1 0.591 6
 UniProt:Q9ERU9 Ranbp2  5 0.564 2
 UniProt:Q9UBU9 NXF1  2 0.527 2
 UniProt:P05412 JUN  4 0.462 2