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HMGA1 [cytosol]
Stable Identifier
R-HSA-3004619
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
High mobility group protein HMG-I/HMG-Y, HMGA1_HUMAN, HMGI/Y
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
HIV Infection (Homo sapiens)
HIV Life Cycle (Homo sapiens)
Early Phase of HIV Life Cycle (Homo sapiens)
Integration of provirus (Homo sapiens)
Formation of Pre-Integration Complex (PIC) (Homo sapiens)
PIC (PreIntegration Complex) [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
Formation of RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
Import of PIC to the Host Nucleus (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
Vpr:importin-alpha complex [cytosol] (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
Integrase binds viral DNA ends (Homo sapiens)
PIC (PreIntegration Complex) [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
viral DNA bound with Integrase in PIC [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
Terminal (3' end) cleavage of viral DNA (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
viral DNA bound with Integrase in PIC [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
Host Interactions of HIV factors (Homo sapiens)
APOBEC3G mediated resistance to HIV-1 infection (Homo sapiens)
Association of APOBEC3G with Gag (Homo sapiens)
APOBEC3G:HIV-1PIC [cytosol] (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
Interactions of Vpr with host cellular proteins (Homo sapiens)
Vpr-mediated nuclear import of PICs (Homo sapiens)
Interaction of Vpr with importin alpha (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
Vpr:importin-alpha complex [cytosol] (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
Vpr binds nucleoporins (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
PIC anchored to the NPC [nuclear envelope] (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
HMGA1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P17096 HMGA1
Gene Names
HMGA1, HMGIY
Chain
initiator methionine:, chain:2-107
Reference Genes
BioGPS Gene:3159 HMGA1
COSMIC (genes):HMGA1 HMGA1
CTD Gene:3159 HMGA1
dbSNP Gene:3159 HMGA1
ENSEMBL:ENSG00000137309 HMGA1
ENSEMBL_homo_sapiens_GENE:ENSG00000137309.21 HMGA1
HGNC:5010 HMGA1
KEGG Gene (Homo sapiens):3159 HMGA1
Monarch:3159 HMGA1
NCBI Gene:3159 HMGA1
OMIM:600701 HMGA1
UCSC:P17096 HMGA1
Reference Transcript
RefSeq:NM_001319080.1 HMGA1
RefSeq:NM_001319079.1 HMGA1
RefSeq:NM_001319082.1 HMGA1
RefSeq:NM_001319081.1 HMGA1
RefSeq:NM_145899.2 HMGA1
RefSeq:NM_001319078.1 HMGA1
RefSeq:NM_002131.3 HMGA1
RefSeq:NM_001319077.1 HMGA1
RefSeq:NM_145903.2 HMGA1
RefSeq:NM_145901.2 HMGA1
RefSeq:NM_145902.2 HMGA1
RefSeq:NM_145905.2 HMGA1
Other Identifiers
11747361_x_at
11753571_x_at
11753817_x_at
17007620
17117871
206074_3p_s_at
206074_PM_s_at
206074_s_at
210457_3p_x_at
210457_PM_x_at
210457_x_at
2904044
2904045
2904046
2904047
2904048
2904049
2904051
2904054
2904055
2904056
2904057
2904058
2904060
2904066
2904067
2904068
2904069
2904070
2904079
3159
3471201
39704_s_at
3972433
64363_f_at
8118794
8180307
8180308
A_23_P42331
A_24_P222043
GE659143
GO:0000785
GO:0000978
GO:0000987
GO:0001221
GO:0003677
GO:0003680
GO:0003682
GO:0003712
GO:0003713
GO:0003723
GO:0003824
GO:0003906
GO:0005198
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005829
GO:0005925
GO:0006260
GO:0006268
GO:0006281
GO:0006284
GO:0006325
GO:0006337
GO:0006351
GO:0006355
GO:0008285
GO:0008301
GO:0016829
GO:0019899
GO:0030374
GO:0030527
GO:0035985
GO:0042974
GO:0042975
GO:0043226
GO:0045892
GO:0045893
GO:0045944
GO:0046965
GO:0051575
GO:0060090
GO:0090402
GO:0090575
GO:0098772
GO:0140097
GO:0140110
GO:0140677
HMNXSV003015779
ILMN_1693560
ILMN_1742699
ILMN_2311537
L17131_rna1_at
PH_hs_0034458
TC06000501.hg
TC06002746.hg
g4504432_3p_s_at
g4504432_3p_x_at
g5834272_3p_s_at
Participates
as an input of
Formation of RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 (Homo sapiens)
as a component of
RTC with integration competent viral DNA:BANF1:HMGA1:PSIP1 [cytosol] (Homo sapiens)
viral DNA bound with Integrase in PIC [cytosol] (Homo sapiens)
PIC (PreIntegration Complex) [cytosol] (Homo sapiens)
IN bound to sticky 3' ends of viral DNA in PIC [cytosol] (Homo sapiens)
Other forms of this molecule
HMGA1 [nucleoplasm]
Cross References
RefSeq
NP_665906.1
,
NP_001306007.1
,
NP_665909.1
,
NP_002122.1
,
NP_665908.1
,
NP_001306006.1
,
NP_001306008.1
,
NP_665910.1
,
NP_001306010.1
,
NP_001306009.1
,
NP_665912.1
,
NP_001306011.1
OpenTargets
ENSG00000137309
HPA
ENSG00000137309-HMGA1
GeneCards
P17096
Ensembl
ENSP00000399888
,
ENSP00000308227
,
ENST00000374116
,
ENSG00000137309
,
ENST00000347617
,
ENSP00000288245
,
ENST00000447654
,
ENSP00000385693
,
ENSP00000363230
,
ENST00000311487
,
ENST00000401473
PRO
P17096
Pharos - Targets
P17096
PDB
2EZD
,
2EZG
,
2EZF
,
2EZE
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y5N6 ORC6
4
ORC6 [nucleoplasm]
(R-HSA-68539)
ORC6 [cytosol]
(R-HSA-9734663)
p-T195-ORC6 [cytosol]
(R-HSA-9734682)
p-T195-ORC6 [nucleoplasm]
(R-HSA-9734715)
0.602
4
UniProt:P17676 CEBPB
3
p-T235, S321-CEBPB [nucleoplasm]
(R-HSA-3857339)
p-T235-CEBPB [nucleoplasm]
(R-HSA-3857343)
CEBPB [nucleoplasm]
(R-HSA-381378)
0.544
3
UniProt:P08047 SP1
1
SP1 [nucleoplasm]
(R-HSA-1592223)
0.544
4
IntAct:EBI-1566868 IL2RA
0.525
3
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