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HNF1B [nucleoplasm]
Stable Identifier
R-HSA-3004721
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Hepatocyte nuclear factor 1-beta, HNF1B_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Regulation of beta-cell development (Homo sapiens)
Regulation of gene expression in early pancreatic precursor cells (Homo sapiens)
HNF1B- and FGF10-dependent synthesis of PTF1A protein (Homo sapiens)
HNF1B [nucleoplasm] (Homo sapiens)
HNF1B-dependent synthesis of HNF6 protein (Homo sapiens)
HNF1B [nucleoplasm] (Homo sapiens)
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells (Homo sapiens)
HNF6-dependent synthesis of HNF1B protein (Homo sapiens)
HNF1B [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P35680 HNF1B
Gene Names
HNF1B, TCF2
Chain
chain:1-557
Reference Genes
BioGPS Gene:6928 HNF1B
CTD Gene:6928 HNF1B
dbSNP Gene:6928 HNF1B
ENSEMBL:ENSG00000275410 HNF1B
ENSEMBL:ENSG00000276194 HNF1B
HGNC:11630 HNF1B
KEGG Gene (Homo sapiens):6928 HNF1B
Monarch:6928 HNF1B
NCBI Gene:6928 HNF1B
OMIM:189907 HNF1B
UCSC:P35680 HNF1B
Reference Transcript
RefSeq:NM_000458.3 HNF1B
RefSeq:NM_001304286.1 HNF1B
RefSeq:NM_001165923.3 HNF1B
Other Identifiers
0001170497
0001170692
11725253_at
11752480_a_at
16843853
205313_at
3754795
3754796
3754798
3754799
3754800
3754801
3754805
3754806
3754807
3754808
3754812
3754823
3754824
3754825
3754826
3754827
3754828
3754831
3754832
38506_at
6928
711_at
8014591
A_23_P409287
A_24_P330822
GO:0000122
GO:0000228
GO:0000790
GO:0000976
GO:0000977
GO:0000981
GO:0000987
GO:0001714
GO:0001822
GO:0001826
GO:0001889
GO:0003674
GO:0003677
GO:0003700
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0006357
GO:0006810
GO:0007165
GO:0007219
GO:0007267
GO:0007492
GO:0008150
GO:0008219
GO:0008283
GO:0009058
GO:0009743
GO:0009749
GO:0009790
GO:0009952
GO:0010628
GO:0014070
GO:0015031
GO:0022607
GO:0030073
GO:0030111
GO:0030154
GO:0030902
GO:0031016
GO:0032922
GO:0032991
GO:0034641
GO:0035565
GO:0039020
GO:0040007
GO:0042493
GO:0042802
GO:0043066
GO:0043226
GO:0043231
GO:0043565
GO:0044877
GO:0045893
GO:0045944
GO:0048557
GO:0048598
GO:0048646
GO:0048754
GO:0048793
GO:0048856
GO:0050673
GO:0060261
GO:0060429
GO:0060677
GO:0060993
GO:0061017
GO:0061296
GO:0065003
GO:0065004
GO:0070365
GO:0072095
GO:0072164
GO:0072176
GO:0072177
GO:0072179
GO:0072181
GO:1900212
ILMN_1663561
ILMN_1778337
ILMN_3235709
TC17001410.hg
g4507396_3p_at
Participant Of
output
HNF6-dependent synthesis of HNF1B protein
This entity regulates
Positively
HNF1B-dependent synthesis of HNF6 protein
HNF1B- and FGF10-dependent synthesis of PTF1A protein
Cross References
RefSeq
NP_001159395.1
,
NP_000449.1
,
NP_001291215.1
OpenTargets
ENSG00000275410
GeneCards
P35680
HPA
ENSG00000275410-HNF1B
Ensembl
ENSP00000482711
,
ENSP00000480291
,
ENSP00000484591
,
ENST00000633792
,
ENST00000617811
,
ENST00000621123
,
ENSG00000275410
,
ENSP00000488080
,
ENST00000610754
,
ENSG00000276194
PRO
P35680
Orphanet
17228
PDB
2DA6
,
5K9S
,
2H8R
Interactors (12)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q70EL1-9 USP54
0.556
3
UniProt:P78424 PO6F2
0.556
3
UniProt:Q8TDS5 OXER1
1
OXER1 [plasma membrane]
(R-HSA-416425)
0.556
3
UniProt:O43186 CRX
0.556
3
UniProt:P32243-2 OTX2
0.556
3
UniProt:Q6NVU6 UFSP1
0.556
3
UniProt:Q08AM6 VAC14
3
VAC14 [early endosome membrane]
(R-HSA-1806207)
VAC14 [late endosome membrane]
(R-HSA-1806219)
VAC14 [Golgi membrane]
(R-HSA-1806235)
0.556
3
UniProt:Q5SWW7 CJ055
0.556
3
UniProt:Q6PEX3 KRTAP26-1
1
KRTAP26-1 [cytosol]
(R-HSA-6810244)
0.556
3
UniProt:Q9NP55 BPIFA1
1
BPIFA1 [extracellular region]
(R-HSA-6809280)
0.556
3
UniProt:P61457 PCBD1
1
PCBD1 [cytosol]
(R-HSA-71131)
0.556
3
UniProt:P55197-2 MLLT10
0.556
3
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