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ITGB7 [plasma membrane]
Stable Identifier
R-HSA-3006427
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Integrin beta-7, ITB7_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
Interaction of integrin alphaEbeta7 with Cadherin-1 (Homo sapiens)
Integrin alphaEbeta7 [plasma membrane] (Homo sapiens)
ITGB7 [plasma membrane] (Homo sapiens)
Integrin alphaEbeta7:Cadherin-1 [plasma membrane] (Homo sapiens)
Integrin alphaEbeta7 [plasma membrane] (Homo sapiens)
ITGB7 [plasma membrane] (Homo sapiens)
MADCAM1-1 binds Integrin alpha4beta7 (Homo sapiens)
Integrin alpha4beta7 [plasma membrane] (Homo sapiens)
ITGB7 [plasma membrane] (Homo sapiens)
Integrin alpha4beta7:MADCAM1 [plasma membrane] (Homo sapiens)
Integrin alpha4beta7 [plasma membrane] (Homo sapiens)
ITGB7 [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
MADCAM1-1 binds Integrin alpha4beta7 (Homo sapiens)
Integrin alpha4beta7 [plasma membrane] (Homo sapiens)
ITGB7 [plasma membrane] (Homo sapiens)
Integrin alpha4beta7:MADCAM1 [plasma membrane] (Homo sapiens)
Integrin alpha4beta7 [plasma membrane] (Homo sapiens)
ITGB7 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:P26010 ITGB7
Gene Names
ITGB7
Chain
signal peptide:1-19, chain:20-798
Reference Genes
BioGPS Gene:3695 ITGB7
COSMIC (genes):ITGB7 ITGB7
CTD Gene:3695 ITGB7
dbSNP Gene:3695 ITGB7
ENSEMBL:ENSG00000139626 ITGB7
ENSEMBL_homo_sapiens_GENE:ENSG00000139626.16 ITGB7
HGNC:6162 ITGB7
KEGG Gene (Homo sapiens):3695 ITGB7
Monarch:3695 ITGB7
NCBI Gene:3695 ITGB7
OMIM:147559 ITGB7
UCSC:P26010 ITGB7
Reference Transcript
RefSeq:XM_005268851.3 ITGB7
RefSeq:NM_000889.2 ITGB7
RefSeq:XM_005268852.4 ITGB7
Other Identifiers
11725966_a_at
11756701_a_at
16765226
2019_s_at
205718_PM_at
205718_at
3456050
3456051
3456053
3456054
3456057
3456059
3456060
3456061
3456063
3456066
3456067
3456068
3456069
3456072
3456073
3456074
3456075
3456076
3456078
3695
7963614
A_23_P76529
GE58047
GO:0001618
GO:0002376
GO:0002387
GO:0003366
GO:0005178
GO:0005515
GO:0005576
GO:0005615
GO:0005886
GO:0005925
GO:0007155
GO:0007160
GO:0007229
GO:0008305
GO:0009986
GO:0016020
GO:0023052
GO:0034113
GO:0034446
GO:0034669
GO:0043113
GO:0043226
GO:0043235
GO:0046718
GO:0046872
GO:0048870
GO:0050839
GO:0050900
GO:0050901
GO:0070062
GO:0072678
HMNXSV003023690
ILMN_1777519
PH_hs_0000237
S80335_at
TC12001544.hg
g4504776_3p_at
Participates
as a component of
Integrin alpha4beta7 [plasma membrane] (Homo sapiens)
Integrin alphaEbeta7 [plasma membrane] (Homo sapiens)
Inferred To
itgb7 [plasma membrane]
(Xenopus tropicalis)
pat-3 [plasma membrane]
(Caenorhabditis elegans)
mys [plasma membrane]
(Drosophila melanogaster)
Homologues of ITGB7 [plasma membrane]
(Caenorhabditis elegans)
Homologues of ITGB7 [plasma membrane]
(Drosophila melanogaster)
ITGB7 [plasma membrane]
(Bos taurus)
ITGB7 [plasma membrane]
(Caenorhabditis elegans)
ITGB7 [plasma membrane]
(Canis familiaris)
ITGB7 [plasma membrane]
(Mus musculus)
ITGB7 [plasma membrane]
(Sus scrofa)
Itgb7 [plasma membrane]
(Rattus norvegicus)
Itgbn [plasma membrane]
(Drosophila melanogaster)
Cross References
RefSeq
XP_005268909.1
,
NP_000880.1
,
XP_005268908.1
Guide to Pharmacology - Targets
2461
OpenTargets
ENSG00000139626
GeneCards
P26010
HPA
ENSG00000139626-ITGB7
Ensembl
ENSP00000408741
,
ENSP00000455374
,
ENSP00000267082
,
ENST00000422257
,
ENST00000550743
,
ENSG00000139626
,
ENST00000267082
PRO
P26010
Pharos - Targets
P26010
PDB
3V4V
,
3V4P
,
2BRQ
HMDB Protein
HMDBP07742
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P21333 FLNA
3
FLNA [extracellular region]
(R-HSA-350712)
p-S2152-FLNA [cytosol]
(R-HSA-5669246)
FLNA [cytosol]
(R-HSA-210019)
0.737
7
UniProt:P97465
2
phospho-Dok1 [cytosol]
(R-MMU-8848784)
Dok1 [cytosol]
(R-MMU-74763)
0.544
2
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