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RPTOR [cytosol]
Stable Identifier
R-HSA-3006727
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Regulatory-associated protein of mTOR, RPTOR_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Autophagy (Homo sapiens)
Macroautophagy (Homo sapiens)
Active MTORC1 binds the ULK1 complex (Homo sapiens)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
Active MTORC1 phosphorylates ULK1 (Homo sapiens)
MTORC1:RHEB:GTP:ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
Rheb in the MTORC1 complex hydrolyses GTP (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Homo sapiens)
MTORC1:RHEB:GTP:p-S758-ULK1:ATG13:RB1CC1:ATG101 [lysosomal membrane] (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
Cellular responses to external stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Amino acids regulate mTORC1 (Homo sapiens)
RRAGA,B hydrolyzes GTP (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1 binds RHEB:GTP (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Metabolic Genes (Homo sapiens)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
PIP3 activates AKT signaling (Homo sapiens)
PTEN Regulation (Homo sapiens)
Regulation of PTEN gene transcription (Homo sapiens)
MAF1 translocates to the nucleus (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1 phosphorylates MAF1 (Homo sapiens)
MTORC1:Ragulator:Rag:GNP:RHEB:GTP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
MTOR signalling (Homo sapiens)
AKT1S1 (PRAS40) binds mTORC1 (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Homo sapiens)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
Energy dependent regulation of mTOR by LKB1-AMPK (Homo sapiens)
AMPK phosphorylates Raptor in the mTORC1 complex (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
RHEB in mTORC1:RHEB:GTP hydrolyses GTP (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1:Ragulator:Rag:GNP:RHEB:GDP [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
Formation of active mTORC1 complex (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
Phosphorylated AKT1S1:mTORC1 binds YWHAB (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
Ragulator:Rag dimers:SLC38A9 bind mTORC1 (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1 phosphorylates AKT1S1 (Homo sapiens)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-S183,T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1-mediated signalling (Homo sapiens)
Phosphorylation of 4E-BP1 by activated mTORC1 (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1:RHEB:GTP:AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
mTORC1:p-T246-AKT1S1:YWHAB [lysosomal membrane] (Homo sapiens)
mTORC1:RHEB:GTP:p-T246-AKT1S1 [lysosomal membrane] (Homo sapiens)
Active mTORC1 complex [lysosomal membrane] (Homo sapiens)
mTORC1:Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane] (Homo sapiens)
mTORC1 [cytosol] (Homo sapiens)
RPTOR [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8N122 RPTOR
Gene Names
RPTOR, KIAA1303, RAPTOR
Chain
chain:1-1335
Reference Genes
BioGPS Gene:57521 RPTOR
COSMIC (genes):RPTOR RPTOR
CTD Gene:57521 RPTOR
dbSNP Gene:57521 RPTOR
ENSEMBL:ENSG00000141564 RPTOR
HGNC:30287 RPTOR
KEGG Gene (Homo sapiens):57521 RPTOR
Monarch:57521 RPTOR
NCBI Gene:57521 RPTOR
OMIM:607130 RPTOR
UCSC:Q8N122 RPTOR
Reference Transcript
RefSeq:NM_020761.2 RPTOR
RefSeq:NM_001163034.1 RPTOR
Other Identifiers
0002850338
11722496_a_at
11722497_a_at
11722498_s_at
11745456_a_at
11752252_a_at
16838698
225715_at
3737489
3737490
3737491
3737500
3737502
3737519
3737528
3737534
3737539
3737551
3737552
3737553
3737560
3737563
3737565
3737568
3737578
3737581
3737582
3737583
3737584
3737585
3737586
3737593
3737601
3737602
3737604
3737608
3737614
3737615
3737617
3737621
3737623
3737624
3737625
3737626
3737627
3737628
56274_at
57521
8010512
A_14_P113638
A_14_P125470
A_23_P384499
GE53894
GO:0000278
GO:0001002
GO:0001003
GO:0001006
GO:0001156
GO:0001558
GO:0001938
GO:0003674
GO:0003677
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005764
GO:0005765
GO:0005773
GO:0005829
GO:0006464
GO:0006914
GO:0006950
GO:0007049
GO:0007050
GO:0007165
GO:0008134
GO:0008150
GO:0008283
GO:0008361
GO:0009056
GO:0009058
GO:0009267
GO:0010494
GO:0010506
GO:0010800
GO:0016032
GO:0016241
GO:0019899
GO:0019901
GO:0030234
GO:0030291
GO:0030295
GO:0030307
GO:0030425
GO:0030674
GO:0031669
GO:0031929
GO:0031931
GO:0032008
GO:0032147
GO:0032991
GO:0033138
GO:0034641
GO:0038202
GO:0040007
GO:0042325
GO:0043025
GO:0043226
GO:0044403
GO:0044877
GO:0045945
GO:0071230
GO:0071233
GO:0071889
GO:0071901
GO:0071902
GO:1900034
GO:1900087
Hs.20677.0.S1_3p_at
ILMN_1793514
ILMN_1797816
PH_hs_0023108
TC17000921.hg
Participant Of
hasComponent
mTORC1 [cytosol]
Other forms of this molecule
p-S722,S792-RPTOR [cytosol]
RPTOR [nucleoplasm]
Inferred To
mip1 [cytosol] (Schizosaccharomyces pombe)
rptor [cytosol] (Danio rerio)
rptor [cytosol] (Xenopus tropicalis)
RPTOR [cytosol] (Bos taurus)
RPTOR [cytosol] (Canis familiaris)
RPTOR [cytosol] (Gallus gallus)
RPTOR [cytosol] (Sus scrofa)
raptor [cytosol] (Dictyostelium discoideum)
raptor [cytosol] (Drosophila melanogaster)
KOG1 [cytosol] (Saccharomyces cerevisiae)
Rptor [cytosol] (Mus musculus)
Rptor [cytosol] (Rattus norvegicus)
daf-15 [cytosol] (Caenorhabditis elegans)
Cross References
RefSeq
NP_001156506.1
,
NP_065812.1
OpenTargets
ENSG00000141564
GeneCards
Q8N122
HPA
ENSG00000141564-RPTOR
Ensembl
ENST00000544334
,
ENST00000570891
,
ENSG00000141564
,
ENSP00000442479
,
ENSP00000460136
,
ENST00000306801
,
ENSP00000307272
PRO
Q8N122
Orphanet
24876
PDB
6BCU
,
6SB2
,
6BCX
,
6SB0
,
5H64
,
6U62
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13541 EIF4EBP1
2
p-T37,T46-EIF4EBP1 [cytosol]
(R-HSA-165685)
EIF4EBP1 [cytosol]
(R-HSA-72580)
0.711
5
UniProt:Q96B36 AKT1S1
5
p-S183,T246-AKT1S1 [cytosol]
(R-HSA-5672863)
AKT1S1 [nucleoplasm]
(R-HSA-5083637)
p-T246-AKT1S1 [cytosol]
(R-HSA-377124)
p-S183,T246-AKT1S1 [cytosol]
(R-HSA-200163)
AKT1S1 [cytosol]
(R-HSA-200155)
0.564
4
UniProt:P15056 BRAF
68
BRAF-MACF1fusion [cytosol]
(R-HSA-6802402)
p-S,T-BRAF [cytosol]
(R-HSA-169856)
p-BRAF-MACF1 fusion [cytosol]
(R-HSA-6802536)
BRAF [cytosol]
(R-HSA-167224)
BRAF E501G [cytosol]
(R-HSA-9651132)
BRAF D594N [cytosol]
(R-HSA-6802299)
BRAF D638E [cytosol]
(R-HSA-9651125)
BRAF G596R [cytosol]
(R-HSA-6802385)
BRAF D594V [cytosol]
(R-HSA-6802305)
BRAF G596V [cytosol]
(R-HSA-9651138)
BRAF G466E [cytosol]
(R-HSA-6802374)
BRAF D594G [cytosol]
(R-HSA-6802295)
BRAF L505H [cytosol]
(R-HSA-9648845)
BRAF F595L [cytosol]
(R-HSA-6802316)
BRAF L597V [cytosol]
(R-HSA-6802397)
BRAF G464E [cytosol]
(R-HSA-6802369)
BRAF N581D [cytosol]
(R-HSA-9651152)
BRAF E586K [cytosol]
(R-HSA-6802308)
BRAF V600K [cytosol]
(R-HSA-6802502)
BRAF A246P [cytosol]
(R-HSA-9651123)
BRAF G469V [cytosol]
(R-HSA-9648620)
BRAF T244P [cytosol]
(R-HSA-9651165)
BRAF G469R [cytosol]
(R-HSA-9648621)
BRAF L597R [cytosol]
(R-HSA-9648617)
BRAF G469E [cytosol]
(R-HSA-9648618)
BRAF L597Q [cytosol]
(R-HSA-9648619)
BRAF G466A [cytosol]
(R-HSA-9648613)
BRAF G466V [cytosol]
(R-HSA-9648838)
BRAF N581S [cytosol]
(R-HSA-9648850)
BRAF G464V [cytosol]
(R-HSA-9648611)
p-BRAF L597V [plasma membrane]
(R-HSA-8936647)
p-BRAF L505H [plasma membrane]
(R-HSA-9648862)
p-BRAF G464E [plasma membrane]
(R-HSA-8936645)
p-BRAF F595L [plasma membrane]
(R-HSA-8936641)
p-BRAF A246P [plasma membrane]
(R-HSA-9651188)
p-BRAF E586K [plasma membrane]
(R-HSA-8936639)
p-BRAF N581D [plasma membrane]
(R-HSA-9651191)
p-BRAF V600K [plasma membrane]
(R-HSA-8936651)
p-BRAF G464V [plasma membrane]
(R-HSA-9648633)
p-BRAF T244P [plasma membrane]
(R-HSA-9651194)
p-BRAF G469E [plasma membrane]
(R-HSA-9648634)
p-BRAF G466V [plasma membrane]
(R-HSA-9648859)
p-BRAF G469V [plasma membrane]
(R-HSA-9648628)
p-BRAF G466A [plasma membrane]
(R-HSA-9648629)
p-BRAF L597Q [plasma membrane]
(R-HSA-9648630)
p-BRAF L597R [plasma membrane]
(R-HSA-9648631)
p-BRAF N581S [plasma membrane]
(R-HSA-9648866)
p-BRAF G469R [plasma membrane]
(R-HSA-9648627)
BRAF 599dupT [cytosol]
(R-HSA-6802281)
BRAF G534R [cytosol]
(R-HSA-9651134)
BRAF S467A [cytosol]
(R-HSA-9651161)
BRAF K601N [cytosol]
(R-HSA-9648857)
BRAF G469A [cytosol]
(R-HSA-6802381)
BRAF L485F [cytosol]
(R-HSA-9651147)
BRAF Q257R [cytosol]
(R-HSA-9651157)
BRAF K499E [cytosol]
(R-HSA-9651142)
BRAF V600E [cytosol]
(R-HSA-6802498)
BRAF K601E [cytosol]
(R-HSA-9648833)
BRAF V600E V169_M438del [cytosol]
(R-HSA-6802489)
BRAF V600E V47_D380del [cytosol]
(R-HSA-6802491)
BRAF V600E V47_M438del [cytosol]
(R-HSA-6802495)
V600E BRAF V169_D380del [cytosol]
(R-HSA-6802486)
p-S445,S729-BRAF [plasma membrane]
(R-HSA-8933622)
hyperphosphorylated BRAF [plasma membrane]
(R-HSA-5675199)
p-S365,S445,S729 BRAF [cytosol]
(R-HSA-5672667)
p-S445,T599,S602,S729 BRAF [plasma membrane]
(R-HSA-5672679)
p-S445,S729-BRAF [cytosol]
(R-HSA-5672673)
p-S445,T599,S602,S729 BRAF [cytosol]
(R-HSA-5672676)
0.527
2
UniProt:O43504 LAMTOR5
1
LAMTOR5 [lysosomal membrane]
(R-HSA-5655441)
0.527
2
UniProt:Q0VGL1 LAMTOR4
1
LAMTOR4 [lysosomal membrane]
(R-HSA-5655432)
0.527
2
UniProt:Q6IAA8 LAMTOR1
5
LAMTOR1 [ficolin-1-rich granule membrane]
(R-HSA-6801003)
LAMTOR1 [lysosomal membrane]
(R-HSA-5653582)
LAMTOR1 [plasma membrane]
(R-HSA-6806270)
LAMTOR1 [azurophil granule membrane]
(R-HSA-6799633)
LAMTOR1 [specific granule membrane]
(R-HSA-6799631)
0.527
2
UniProt:P67999
2
phospho-Rps6kb1 [cytosol]
(R-RNO-165714)
Rps6kb1 [cytosol]
(R-RNO-165716)
0.499
2
UniProt:O75385 ULK1
7
ULK1 [cytosol]
(R-HSA-1632847)
ULK1 [recycling endosome]
(R-HSA-8854761)
ULK1 [mitochondrial outer membrane]
(R-HSA-8948145)
p-T180,S317,S467,S556,S638,T575-ULK1 [endoplasmic reticulum membrane]
(R-HSA-8948047)
p-T180,S317,S467,S556,S638,T575-ULK1 [cytosol]
(R-HSA-5675858)
p-S317,467,556,638,T575-ULK1 [cytosol]
(R-HSA-5673747)
p-S758-ULK1 [cytosol]
(R-HSA-5672131)
0.499
3
UniProt:P45983 MAPK8
3
p-T,Y-MAPK8 [cytosol]
(R-HSA-194371)
MAPK8 [cytosol]
(R-HSA-168141)
p-T,Y-MAPK8 [nucleoplasm]
(R-HSA-216349)
0.499
6
UniProt:Q96EB6 SIRT1
1
SIRT1 [nucleoplasm]
(R-HSA-427531)
0.499
3
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