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About
What is Reactome ?
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Digital Preservation
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RBPJ [nucleoplasm]
Stable Identifier
R-HSA-3008668
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Recombining binding protein suppressor of hairless, SUH_HUMAN, CBF1
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Gastrulation (Homo sapiens)
Formation of paraxial mesoderm (Homo sapiens)
Expression of TBX6 in paraxial mesoderm (Homo sapiens)
NOTCH1 coactivator complex:TBX6 gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 coactivator complex binds the TBX6 gene (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 coactivator complex:TBX6 gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Somitogenesis (Homo sapiens)
Expression of HES7 in presomitic mesoderm (Homo sapiens)
HES7:LEF1:CTNNB1:TBX6:RBPJ:NICD1:HES7 gene [nucleoplasm] (Homo sapiens)
RBPJ:NICD1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
LEF1:CTNNB1:TBX6:RBPJ:NICD1:HES7 gene [nucleoplasm] (Homo sapiens)
RBPJ:NICD1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Expression of LFNG in presomitic mesoderm (Homo sapiens)
HES7:RBPJ:NICD1:MSGN1:LFNG gene [nucleoplasm] (Homo sapiens)
RBPJ:NICD1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ:NICD1:MSGN1:LFNG gene [nucleoplasm] (Homo sapiens)
RBPJ:NICD1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
HES7 binds the HES7 gene (Homo sapiens)
HES7:LEF1:CTNNB1:TBX6:RBPJ:NICD1:HES7 gene [nucleoplasm] (Homo sapiens)
RBPJ:NICD1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
LEF1:CTNNB1:TBX6:RBPJ:NICD1:HES7 gene [nucleoplasm] (Homo sapiens)
RBPJ:NICD1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
HES7 binds the LFNG gene (Homo sapiens)
HES7:RBPJ:NICD1:MSGN1:LFNG gene [nucleoplasm] (Homo sapiens)
RBPJ:NICD1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ:NICD1:MSGN1:LFNG gene [nucleoplasm] (Homo sapiens)
RBPJ:NICD1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
LEF1:CTNNB1, NICD1 (NOTCH1) and TBX6 bind the HES7 gene in presomitic mesoderm (Homo sapiens)
LEF1:CTNNB1:TBX6:RBPJ:NICD1:HES7 gene [nucleoplasm] (Homo sapiens)
RBPJ:NICD1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ:NICD1 and MSGN1 bind the LFNG gene (Homo sapiens)
RBPJ:NICD1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ:NICD1:MSGN1:LFNG gene [nucleoplasm] (Homo sapiens)
RBPJ:NICD1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Regulation of beta-cell development (Homo sapiens)
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells (Homo sapiens)
NOTCH1 stimulates HES1 transcription (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Disease (Homo sapiens)
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
Signaling by NOTCH1 in Cancer (Homo sapiens)
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer (Homo sapiens)
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants (Homo sapiens)
CDK8 phosphorylates NICD1 PEST domain mutants (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:CDK8:CCNC [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants displace co-repressor complex from RBPJ (CSL) (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ:NCOR corepressor complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants in complex with RBPJ (CSL) bind MAML (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants bind HES1 promoter (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants bind HES5 promoter (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HES5 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants bind MYC promoter (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:MYC Gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants bind promoters of HEY genes (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HEY Genes [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants coactivator complex binds CDK8:CCNC (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:CDK8:CCNC [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants stimulate HES1 transcription (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants stimulate HES5 transcription (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HES5 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants stimulate HEY transcription (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HEY Genes [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants stimulate MYC transcription (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:MYC Gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Signaling by NOTCH1 PEST Domain Mutants in Cancer (Homo sapiens)
Constitutive Signaling by NOTCH1 PEST Domain Mutants (Homo sapiens)
CDK8 phosphorylates NICD1 PEST domain mutants (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:CDK8:CCNC [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants displace co-repressor complex from RBPJ (CSL) (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ:NCOR corepressor complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants in complex with RBPJ (CSL) bind MAML (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants bind HES1 promoter (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants bind HES5 promoter (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HES5 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants bind MYC promoter (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:MYC Gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants bind promoters of HEY genes (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HEY Genes [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants coactivator complex binds CDK8:CCNC (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:CDK8:CCNC [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants stimulate HES1 transcription (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants stimulate HES5 transcription (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HES5 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants stimulate HEY transcription (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:HEY Genes [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST domain mutants stimulate MYC transcription (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex:MYC Gene [nucleoplasm] (Homo sapiens)
NOTCH1 PEST Domain Mutants Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Notch-HLH transcription pathway (Homo sapiens)
Formation of CSL NCOR corepressor complex (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ:NCOR corepressor complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Formation of CSL-NICD coactivator complex (Homo sapiens)
CSL NICD coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Transcriptional regulation by RUNX3 (Homo sapiens)
RUNX3 regulates NOTCH signaling (Homo sapiens)
HES1 gene transcription is inhibited by RUNX3 (Homo sapiens)
RUNX3:NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RUNX3:NOTCH1 coactivator complex:HES1 gene [nucleoplasm] (Homo sapiens)
RUNX3:NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex binds HES1 promoter (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 stimulates HES1 transcription (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RUNX3 binds the NOTCH1 coactivator complex (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RUNX3:NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RUNX3:NOTCH1 coactivator complex binds the HES1 gene promoter (Homo sapiens)
RUNX3:NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RUNX3:NOTCH1 coactivator complex:HES1 gene [nucleoplasm] (Homo sapiens)
RUNX3:NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by NOTCH (Homo sapiens)
Pre-NOTCH Expression and Processing (Homo sapiens)
Pre-NOTCH Transcription and Translation (Homo sapiens)
NOTCH1 coactivator complex binds NOTCH3 gene (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 coactivator complex:NOTCH3 gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 gene transcription (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 gene transcription (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 coactivator complex:NOTCH3 gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Signaling by NOTCH1 (Homo sapiens)
NOTCH1 Intracellular Domain Regulates Transcription (Homo sapiens)
MAML in complex with NICD1 recruits CDK8 (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:CDK8:CCNC [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NICD1 displaces co-repressor complex from RBPJ (CSL) (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ:NCOR corepressor complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NICD1 in complex with RBPJ (CSL) recruits MAML (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NICD1 is phosphorylated by CDK8 (Homo sapiens)
NOTCH1 Coactivator Complex:CDK8:CCNC [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex binds HES1 promoter (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex binds HES5 promoter (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES5 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex binds MYC promoter (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:MYC Gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex binds promoters of HEY genes (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HEY Genes [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 stimulates HES1 transcription (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES1 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 stimulates HES5 transcription (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:HES5 Gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 stimulates HEY transcription (Homo sapiens)
NOTCH1 Coactivator Complex:HEY Genes [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 stimulates MYC transcription (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex:MYC Gene [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Signaling by NOTCH2 (Homo sapiens)
NOTCH2 intracellular domain regulates transcription (Homo sapiens)
NICD2 binds RBPJ and MAML in the nucleus (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 coactivator complex and phosphorylated CREB1 bind GZMB promoter (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 coactivator complex:p-S133-CREB1:EP300:GZMB Gene [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 coactivator complex binds FCER2 promoter (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex:FCER2 gene [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 coactivator complex binds HES1 promoter (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex:HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 coactivator complex binds HES5 promoter (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex:HES5 gene [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 stimulates GZMB transcription (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 coactivator complex:p-S133-CREB1:EP300:GZMB Gene [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 stimulates HES1 transcription (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex:HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 stimulates transcription of FCER2 (CD23A) (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex:FCER2 gene [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 stimulates transcription of HES5 (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex:HES5 gene [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Signaling by NOTCH3 (Homo sapiens)
NOTCH3 Intracellular Domain Regulates Transcription (Homo sapiens)
DLGAP5 gene transcription is stimulated by NOTCH3 (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:DLGAP5 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
FABP7 gene expression is positively regulated by NOTCH1 and NOTCH3 (Homo sapiens)
NOTCH1,NOTCH3 coactivator complexes [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
HES1 gene expression is stimulated by NOTCH3 and STAT1 (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:p-Y701-STAT1 dimer:HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
HES5 gene expression is stimulated by NOTCH3 (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
HEY1 gene expression is positively regulated by NOTCH3 and STAT1 (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
HEY2 gene expression is positively regulated by NOTCH3 (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
HEYL gene expression is stimulated by NOTCH3 (Homo sapiens)
NOTCH3 coactivator complex:HEYL gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NICD3 binds RBPJ and MAML in the nucleus (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1,NOTCH3 coactivator complex binds PLXND1 gene promoter (Homo sapiens)
NOTCH1,NOTCH3 coactivator complex:PLXND1 gene [nucleoplasm] (Homo sapiens)
NOTCH1,NOTCH3 coactivator complexes [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1,NOTCH3 coactivator complexes [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex and STAT1 bind HES1 gene promoter (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:p-Y701-STAT1 dimer:HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex binds DLGAP5 gene promoter (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:DLGAP5 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex binds HES1 gene promoter (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:HES1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex binds HEYL gene promoter (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:HEYL gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex binds PBX1 gene promoter (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:PBX1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex binds WWC1 (Kibra) gene promoter (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:WWC1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex binds the PTCRA gene promoter (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:PTCRA gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
PBX1 gene expression is stimulated by NOTCH3 (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:PBX1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
PLXND1 gene expression is stimulated by NOTCH1,NOTCH3 coactivator complexes (Homo sapiens)
NOTCH1,NOTCH3 coactivator complex:PLXND1 gene [nucleoplasm] (Homo sapiens)
NOTCH1,NOTCH3 coactivator complexes [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH1,NOTCH3 coactivator complexes [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
PTCRA gene expression is stimulated by NOTCH3 and inhibited by IK1 (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:PTCRA gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
WWC1 (Kibra) gene expression is stimulated by NOTCH3 (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex:WWC1 gene [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
Signaling by NOTCH4 (Homo sapiens)
NOTCH4 Intracellular Domain Regulates Transcription (Homo sapiens)
ACTA2 gene expression is stimulated by NOTCH1, NOTCH2 and NOTCH4 (Homo sapiens)
NOTCH1,NOTCH2,NOTCH4 coactivator complex [nucleoplasm] (Homo sapiens)
NOTCH1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH4 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
FLT4 gene expression is stimulated by NOTCH4 (Homo sapiens)
NOTCH4 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH4 coactivator complex:FLT4 gene [nucleoplasm] (Homo sapiens)
NOTCH4 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
HES1 gene expression is stimulated by NOTCH4 (Homo sapiens)
NOTCH4 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
HES5 gene expression is stimulated by NOTCH4 (Homo sapiens)
NOTCH4 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
HEY1 gene expression is stimulated by NOTCH4 (Homo sapiens)
NOTCH4 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
HEY2 gene expression is stimulated by NOTCH4 (Homo sapiens)
NOTCH4 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NICD4 binds RBPJ and MAML in the nucleus (Homo sapiens)
NOTCH4 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH4 binds FLT4 gene promoter (Homo sapiens)
NOTCH4 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
NOTCH4 coactivator complex:FLT4 gene [nucleoplasm] (Homo sapiens)
NOTCH4 coactivator complex [nucleoplasm] (Homo sapiens)
RBPJ [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q06330 RBPJ
Gene Names
RBPJ, IGKJRB, IGKJRB1, RBPJK, RBPSUH
Chain
chain:1-500
Reference Genes
BioGPS Gene:3516 RBPJ
COSMIC (genes):RBPJ RBPJ
CTD Gene:3516 RBPJ
dbSNP Gene:3516 RBPJ
ENSEMBL:ENSG00000168214 RBPJ
ENSEMBL_homo_sapiens_GENE:ENSG00000168214.22 RBPJ
HGNC:5724 RBPJ
KEGG Gene (Homo sapiens):3516 RBPJ
Monarch:3516 RBPJ
NCBI Gene:3516 RBPJ
OMIM:147183 RBPJ
UCSC:Q06330 RBPJ
Reference Transcript
RefSeq:XM_005248161.3 RBPJ
RefSeq:XM_017008173.1 RBPJ
RefSeq:NM_015874.4 RBPJ
RefSeq:XM_017008174.1 RBPJ
RefSeq:NM_203283.2 RBPJ
RefSeq:XM_011513840.2 RBPJ
RefSeq:XM_017008172.1 RBPJ
RefSeq:NM_005349.3 RBPJ
RefSeq:XM_017008175.1 RBPJ
RefSeq:NM_203284.2 RBPJ
Other Identifiers
11739392_a_at
11739393_s_at
11757737_s_at
11762366_s_at
16965642
207785_3p_s_at
207785_PM_s_at
207785_s_at
211974_3p_x_at
211974_PM_x_at
211974_x_at
2722201
2722202
2722204
2722205
2722206
2722207
2722208
2722209
2722210
2722211
2722220
2722228
2722235
2722237
2722239
2722240
2722241
2722242
2722244
2722245
2722246
2722247
2722248
2722251
2722254
2722255
2722256
2722258
2722260
2722261
2722262
2722263
2722264
2722265
2722266
3206395
3516
40818_at
65465_at
8094460
A_23_P29994
GE61651
GE62818
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001228
GO:0001525
GO:0001756
GO:0001837
GO:0001974
GO:0002193
GO:0002376
GO:0002437
GO:0003139
GO:0003151
GO:0003157
GO:0003160
GO:0003176
GO:0003177
GO:0003198
GO:0003214
GO:0003222
GO:0003677
GO:0003682
GO:0003700
GO:0005515
GO:0005634
GO:0005654
GO:0005667
GO:0005694
GO:0005730
GO:0005737
GO:0006091
GO:0006351
GO:0006355
GO:0006357
GO:0006954
GO:0006959
GO:0007155
GO:0007219
GO:0007221
GO:0007507
GO:0008283
GO:0009912
GO:0009957
GO:0010468
GO:0010628
GO:0017053
GO:0021983
GO:0022414
GO:0023052
GO:0030097
GO:0030154
GO:0030182
GO:0030183
GO:0030216
GO:0030279
GO:0030513
GO:0035019
GO:0035912
GO:0036302
GO:0042742
GO:0043011
GO:0043226
GO:0043467
GO:0043565
GO:0045165
GO:0045596
GO:0045892
GO:0045944
GO:0048505
GO:0048733
GO:0048820
GO:0048844
GO:0048856
GO:0050673
GO:0050678
GO:0050679
GO:0060045
GO:0060379
GO:0060412
GO:0060486
GO:0060716
GO:0060844
GO:0061344
GO:0061629
GO:0072089
GO:0072554
GO:0090263
GO:0097101
GO:0098542
GO:0120163
GO:0140110
GO:0140297
GO:1901186
GO:1901189
GO:2000138
GO:2000241
GO:2000647
HMNXSV003036990
Hs.278573.0.S1_3p_a_at
Hs.278573.0.S1_3p_s_at
Hs.278573.0.S1_3p_x_at
Hs.278573.1.S1_3p_a_at
ILMN_1708537
ILMN_1726913
ILMN_2316844
PH_hs_0029801
PH_hs_0032754
TC04001945.hg
TC04001946.hg
g7706215_3p_s_at
Participates
as a component of
NICD1 PEST domain mutants:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ:NICD1 [nucleoplasm] (Homo sapiens)
NOTCH2 Coactivator Complex [nucleoplasm] (Homo sapiens)
Notch4 coactivator complex [nucleoplasm] (Homo sapiens)
NOTCH4 coactivator complex [nucleoplasm] (Homo sapiens)
xNICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
mNICD1 Chimeric Enhancer Complex [nucleoplasm] (Homo sapiens)
CSL NICD coactivator complex [nucleoplasm] (Homo sapiens)
Notch3 coactivator complex [nucleoplasm] (Homo sapiens)
CSL NCOR co-repressor complex [nucleoplasm] (Homo sapiens)
RBPJ:NCOR corepressor complex [nucleoplasm] (Homo sapiens)
NOTCH3 coactivator complex [nucleoplasm] (Homo sapiens)
NICD1:RBPJ:SNW1 [nucleoplasm] (Homo sapiens)
as an input of
LEF1:CTNNB1, NICD1 (NOTCH1) and TBX6 bind the HES7 gene in presomitic mesoderm (Homo sapiens)
NICD2 binds RBPJ and MAML in the nucleus (Homo sapiens)
NICD4 binds RBPJ and MAML in the nucleus (Homo sapiens)
NICD4 binds RBPJ and MAML in the nucleus (Homo sapiens)
Formation of CSL NCOR corepressor complex (Homo sapiens)
Formation of CSL-NICD coactivator complex (Homo sapiens)
NICD3 binds RBPJ and MAML in the nucleus (Homo sapiens)
NICD3 binds RBPJ and MAML in the nucleus (Homo sapiens)
Inferred To
RBPJ [nucleoplasm]
(Bos taurus)
RBPJ [nucleoplasm]
(Canis familiaris)
RBPJ [nucleoplasm]
(Gallus gallus)
RBPJ [nucleoplasm]
(Sus scrofa)
lag-1 [nucleoplasm]
(Caenorhabditis elegans)
cbf11 [nucleoplasm]
(Schizosaccharomyces pombe)
rbpj [nucleoplasm]
(Xenopus tropicalis)
rbpjb [nucleoplasm]
(Danio rerio)
Su(H) [nucleoplasm]
(Drosophila melanogaster)
Rbpj [nucleoplasm]
(Mus musculus)
Rbpj [nucleoplasm]
(Rattus norvegicus)
Cross References
RefSeq
XP_005248218.1
,
NP_056958.3
,
XP_016863662.1
,
NP_976028.1
,
NP_976029.1
,
XP_011512142.1
,
XP_016863664.1
,
XP_016863661.1
,
XP_016863663.1
,
NP_005340.2
OpenTargets
ENSG00000168214
GeneCards
Q06330
HPA
ENSG00000168214-RBPJ
Ensembl
ENST00000507561
,
ENSG00000168214
,
ENST00000680928
,
ENST00000342295
,
ENST00000512671
,
ENSP00000347659
,
ENST00000681484
,
ENSP00000426872
,
ENSP00000305815
,
ENST00000355476
,
ENSP00000354528
,
ENST00000681093
,
ENSP00000345206
,
ENST00000342320
,
ENSP00000340124
,
ENST00000504423
,
ENST00000505958
,
ENSP00000505255
,
ENST00000348160
,
ENSP00000423644
,
ENST00000681264
,
ENSP00000504964
,
ENST00000361572
,
ENSP00000339699
,
ENSP00000505636
,
ENSP00000421804
,
ENSP00000505493
,
ENST00000345843
,
ENSP00000423907
PRO
Q06330
Pharos - Targets
Q06330
Orphanet
21412
PDB
2F8X
,
3V79
,
6PY8
,
3NBN
Interactors (22)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P46531 NOTCH1
20
NOTCH1 L1678P S2 cleavage fragment [extracellular region]
(R-HSA-2730745)
NOTCH1 I1680N S2 cleavage fragment [extracellular region]
(R-HSA-2730744)
NOTCH1 I1718T S2 cleavage fragment [extracellular region]
(R-HSA-2730757)
NOTCH1 A1701P S2 cleavage fragment [plasma membrane]
(R-HSA-2730742)
NOTCH1 V1676D S2 cleavage fragment [extracellular region]
(R-HSA-2730755)
NOTCH1 I1680N Transmembrane Fragment [plasma membrane]
(R-HSA-2684869)
NOTCH1 I1718T Transmembrane Fragment [plasma membrane]
(R-HSA-2684881)
NOTCH1 I1616T Extracellular Fragment [extracellular region]
(R-HSA-2684866)
NOTCH1 L1596H Extracellular Fragment [extracellular region]
(R-HSA-2684853)
NOTCH1 L1678P Transmembrane Fragment [plasma membrane]
(R-HSA-1485591)
NOTCH1 A1701P Transmembrane Fragment [plasma membrane]
(R-HSA-1485585)
NOTCH1 I1616N Extracellular Fragment [extracellular region]
(R-HSA-2684862)
NOTCH1 L1593P Extracellular Fragment [extracellular region]
(R-HSA-1485584)
NOTCH1 R1598P Extracellular Fragment [extracellular region]
(R-HSA-1485592)
NOTCH1 V1576E Extracellular Fragment [extracellular region]
(R-HSA-2684852)
NOTCH1 V1676D Transmembrane Fragment [plasma membrane]
(R-HSA-2684874)
NOTCH1 F1592S Extracellular Fragment [extracellular region]
(R-HSA-2684847)
NOTCH1 L1574Q Extracellular Fragment [extracellular region]
(R-HSA-2691203)
p-NICD1 Q2440* [nucleoplasm]
(R-HSA-2902207)
p-NICD1 Q2395* [nucleoplasm]
(R-HSA-2902205)
0.913
13
UniProt:Q92585 MAML1
1
MAML1 [nucleoplasm]
(R-HSA-212416)
0.892
8
UniProt:Q96K30 RITA1
0.729
10
UniProt:Q96T58 SPEN
1
SPEN [cytosol]
(R-HSA-9715142)
0.688
3
UniProt:P12977 EBNA3
0.646
4
UniProt:P04637 TP53
20
Unfolded TP53 [cytosol]
(R-HSA-6813797)
TP53 [cytosol]
(R-HSA-8869337)
PolyUb-TP53 [nucleoplasm]
(R-HSA-6782509)
polySUMO2,3-K386-TP53 [nucleoplasm]
(R-HSA-2997661)
TP53 F341C [nucleoplasm]
(R-HSA-9726318)
TP53 G334V [nucleoplasm]
(R-HSA-9726126)
TP53 L330H [nucleoplasm]
(R-HSA-9726124)
TP53 A347T [nucleoplasm]
(R-HSA-9726339)
TP53 R337C [nucleoplasm]
(R-HSA-9726118)
TP53 L344P [nucleoplasm]
(R-HSA-9726075)
TP53 L344R [nucleoplasm]
(R-HSA-9726073)
TP53 R337H [nucleoplasm]
(R-HSA-9726169)
TP53 R337P [nucleoplasm]
(R-HSA-9726168)
TP53 L330P [nucleoplasm]
(R-HSA-9726136)
TP53 L348S [nucleoplasm]
(R-HSA-9726366)
TP53 R337L [nucleoplasm]
(R-HSA-9726163)
TP53 K351E [nucleoplasm]
(R-HSA-9726258)
TP53 F338I [nucleoplasm]
(R-HSA-9726358)
TP53 R342P [nucleoplasm]
(R-HSA-9726101)
TP53 L330R [nucleoplasm]
(R-HSA-9726133)
0.645
5
UniProt:Q04721 NOTCH2
18
NOTCH2(1582-1665) [extracellular region]
(R-HSA-157652)
NOTCH2(1666-1696) [plasma membrane]
(R-HSA-157628)
NEXT2 [plasma membrane]
(R-HSA-157225)
NICD2 [cytosol]
(R-HSA-157642)
NICD2 [nucleoplasm]
(R-HSA-157942)
Glc,GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane]
(R-HSA-1911428)
Glc,Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane]
(R-HSA-1911417)
Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH2 [Golgi membrane]
(R-HSA-1911505)
FRINGE-modified NOTCH2 Extracellular Fragment (NECD2) [plasma membrane]
(R-HSA-1911518)
FRINGE-modified NOTCH2 extracellular fragment (NECD2) [Golgi membrane]
(R-HSA-1911520)
Pre-NOTCH2 [endoplasmic reticulum membrane]
(R-HSA-157025)
18xFucT-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane]
(R-HSA-1467363)
18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [endoplasmic reticulum membrane]
(R-HSA-1467379)
18xFucT-16xGlcS-FucS-NOTCH2(26-2471) [Golgi membrane]
(R-HSA-1472874)
NOTCH2(1582-2471) [plasma membrane]
(R-HSA-157228)
18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [extracellular region]
(R-HSA-1983678)
NOTCH2(1582-2471) [Golgi membrane]
(R-HSA-157017)
18xFucT-16xGlcS-FucS-NOTCH2(26-1581) [Golgi membrane]
(R-HSA-1983676)
0.643
3
UniProt:P0C7T5 ATX1L
0.641
7
UniProt:P54253 ATX1
0.641
7
UniProt:O60341 KDM1A
1
KDM1A [nucleoplasm]
(R-HSA-996769)
0.641
4
UniProt:Q6P3S6 FBX42
0.623
5
UniProt:Q9Y618 NCOR2
2
monoSUMO1-K672-NCOR2 [nucleoplasm]
(R-HSA-3927904)
NCOR2 [nucleoplasm]
(R-HSA-442469)
0.621
3
UniProt:Q01705 Notch1
20
Notch1 [endosome membrane]
(R-MMU-9793910)
p-NICD1 [nucleoplasm]
(R-MMU-2064842)
NICD1 [cytosol]
(R-MMU-205738)
N1' [plasma membrane]
(R-MMU-206107)
NTM' [extracellular region]
(R-MMU-206219)
NEXT1 [plasma membrane]
(R-MMU-205889)
NdeltaE [plasma membrane]
(R-MMU-2063913)
Fringe-modified NECD1 [plasma membrane]
(R-MMU-2053928)
Glc,GlcNAc-Fuc-Pre-Notch1 [Golgi membrane]
(R-MMU-2023154)
Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH1 [Golgi membrane]
(R-MMU-1911503)
FRINGE-modified NOTCH1 Extracellular Fragment (NECD1) [Golgi membrane]
(R-MMU-1911511)
NTM [plasma membrane]
(R-MMU-206117)
Notch1 Extracellular Domain (NECD1) [extracellular region]
(R-MMU-2032285)
Glc,Fuc-Pre-Notch1 [Golgi membrane]
(R-MMU-2023160)
Glc,Fuc-Pre-Notch1 [endoplasmic reticulum membrane]
(R-MMU-2023167)
Fuc-Pre-Notch1 [endoplasmic reticulum membrane]
(R-MMU-1985704)
Pre-Notch1 [endoplasmic reticulum membrane]
(R-MMU-1984030)
nicd1 [nucleoplasm]
(R-MMU-189582)
17xFucT-14xGlcS-2xFucS-NOTCH1(19-2555) [Golgi membrane]
(R-MMU-1472872)
NOTCH1(1665-2555) [Golgi membrane]
(R-MMU-157092)
0.611
3
UniProt:P0CJ62 RITA1
0.544
2
UniProt:Q9NW82 WDR70
1
WDR70 [nucleoplasm]
(R-HSA-9770425)
0.527
2
UniProt:Q9UM47 NOTCH3
20
Ub-NICD3 [cytosol]
(R-HSA-9021546)
Ub-NEXT3 [plasma membrane]
(R-HSA-9021545)
p-Y-NICD3 [cytosol]
(R-HSA-9018581)
Glc,GlcNAc-Fuc-Pre-NOTCH3 [Golgi membrane]
(R-HSA-1911429)
Glc,Gal-GlcNAc-Fuc-Pre-NOTCH3 [Golgi membrane]
(R-HSA-1911419)
Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH3 [Golgi membrane]
(R-HSA-1911504)
FRINGE-modified NOTCH3 Extracellular Fragment (NECD3) [plasma membrane]
(R-HSA-1911517)
FRINGE-modified NOTCH3 Extracellular fragment (NECD3) [Golgi membrane]
(R-HSA-1911522)
NOTCH3(40-1628) [extracellular region]
(R-HSA-157639)
NOTCH3(1629-1661) [plasma membrane]
(R-HSA-157657)
NEXT3 [plasma membrane]
(R-HSA-157203)
NICD3 [cytosol]
(R-HSA-157647)
NICD3 [nucleoplasm]
(R-HSA-157928)
Pre-NOTCH3 [endoplasmic reticulum membrane]
(R-HSA-157102)
10xFucT-4xFucS-NOTCH3(40-2321) [endoplasmic reticulum membrane]
(R-HSA-1467382)
14xGlcS-10xFucT-4xFucS-NOTCH3(40-2321) [endoplasmic reticulum membrane]
(R-HSA-1467307)
14xGlcS-10xFucT-4xFucS-NOTCH3(40-2321) [Golgi membrane]
(R-HSA-1472871)
NOTCH3(1572-2321) [plasma membrane]
(R-HSA-157231)
14xGlcS-10xFucT-4xFucS-NOTCH3(40-1571) [extracellular region]
(R-HSA-1983675)
14xGlcS-10xFucT-4xFucS-NOTCH3(40-1571) [Golgi membrane]
(R-HSA-1983672)
0.527
2
UniProt:P12978 EBNA2
0.524
2
UniProt:P03204 EBNA6
0.524
3
UniProt:P03203 EBNA4
0.524
4
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.508
2
UniProt:P51532 SMARCA4
1
SMARCA4 [nucleoplasm]
(R-HSA-201686)
0.499
2
UniProt:Q9UPP1 PHF8
1
PHF8 [nucleoplasm]
(R-HSA-5423096)
0.499
2
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