Reactome | p-T72-ETS2 [nucleoplasm]

p-T72-ETS2 [nucleoplasm]

Stable Identifier

R-HSA-3132735

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P15036 ETS2

Gene Names

ETS2

Chain

chain:1-469

Reference Genes

BioGPS Gene:2114 ETS2

COSMIC (genes):ETS2 ETS2

CTD Gene:2114 ETS2

dbSNP Gene:2114 ETS2

ENSEMBL:ENSG00000157557 ETS2

ENSEMBL_homo_sapiens_GENE:ENSG00000157557.13 ETS2

HGNC:3489 ETS2

KEGG Gene (Homo sapiens):2114 ETS2

Monarch:2114 ETS2

NCBI Gene:2114 ETS2

OMIM:164740 ETS2

UCSC:P15036 ETS2

Reference Transcript

Other Identifiers

11742752_a_at

11758370_s_at

1519_at

16922779

201328_PM_at

201328_at

201329_PM_s_at

201329_s_at

2114

38739_at

3921081

3921082

3921083

3921084

3921085

3921086

3921093

3921098

3921100

3921101

3921102

3921105

3921107

3921108

3921109

3921112

3921115

3921116

3921117

3921118

3921119

3921120

8068593

A_14_P117113

A_23_P257924

A_24_P314179

A_24_P382661

GE54144

GE79512

GE88270

GO:0000122

GO:0000785

GO:0000977

GO:0000978

GO:0000981

GO:0001227

GO:0001501

GO:0001712

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005829

GO:0005886

GO:0006351

GO:0006355

GO:0006357

GO:0007498

GO:0019904

GO:0030154

GO:0035259

GO:0043226

GO:0043565

GO:0045944

GO:0048856

GO:0061629

GO:0090009

GO:0140110

GO:1990837

HMNXSV003039575

Hs.85146.0.A2_3p_at

ILMN_1720158

J04102_at

PH_hs_0023540

TC21000169.hg

g4885220_3p_a_at

Participates

as an input of

as a component of

as a member of

p-T38-ETS1/ p-T72-ETS2 [nucleoplasm] (Homo sapiens)

Other forms of this molecule

ETS2 [nucleoplasm]

Inferred To

phospho-etv2 [nucleoplasm] (Xenopus tropicalis)

Homologues of p-T72-ETS2 [nucleoplasm] (Danio rerio)

Homologues of p-T72-ETS2 [nucleoplasm] (Xenopus tropicalis)

phospho-ETS2 [nucleoplasm] (Bos taurus)

phospho-ETS2 [nucleoplasm] (Canis familiaris)

phospho-ETS2 [nucleoplasm] (Sus scrofa)

phospho-ets2 [nucleoplasm] (Danio rerio)

phospho-ets2 [nucleoplasm] (Xenopus tropicalis)

phospho-p-T72-ETS2 [nucleoplasm] (Gallus gallus)

phospho-Ets2 [nucleoplasm] (Mus musculus)

phospho-Ets2 [nucleoplasm] (Rattus norvegicus)

phospho-ets1 [nucleoplasm] (Xenopus tropicalis)

phospho-etsrp [nucleoplasm] (Danio rerio)

phospho-pnt [nucleoplasm] (Drosophila melanogaster)

Modified Residues

Name

O-phospho-L-threonine at 72

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

XP_016883779.1, XP_005260992.1, NP_005230.1

OpenTargets

ENSG00000157557

GeneCards

P15036

HPA

ENSG00000157557-ETS2

Ensembl

ENST00000662305, ENSP00000499315, ENST00000360938, ENST00000666778, ENSP00000353344, ENSP00000499226, ENSP00000499775, ENST00000653642, ENSP00000354194, ENST00000360214, ENSG00000157557

PRO

P15036

Pharos - Targets

P15036

PDB

4BQA, 4MHV

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04637 TP53	20	Unfolded TP53 [cytosol] (R-HSA-6813797) TP53 [cytosol] (R-HSA-8869337) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) polySUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) TP53 F341C [nucleoplasm] (R-HSA-9726318) TP53 G334V [nucleoplasm] (R-HSA-9726126) TP53 L330H [nucleoplasm] (R-HSA-9726124) TP53 A347T [nucleoplasm] (R-HSA-9726339) TP53 R337C [nucleoplasm] (R-HSA-9726118) TP53 L344P [nucleoplasm] (R-HSA-9726075) TP53 L344R [nucleoplasm] (R-HSA-9726073) TP53 R337H [nucleoplasm] (R-HSA-9726169) TP53 R337P [nucleoplasm] (R-HSA-9726168) TP53 L330P [nucleoplasm] (R-HSA-9726136) TP53 L348S [nucleoplasm] (R-HSA-9726366) TP53 R337L [nucleoplasm] (R-HSA-9726163) TP53 K351E [nucleoplasm] (R-HSA-9726258) TP53 F338I [nucleoplasm] (R-HSA-9726358) TP53 R342P [nucleoplasm] (R-HSA-9726101) TP53 L330R [nucleoplasm] (R-HSA-9726133)	0.602	4
UniProt:Q8NHY2 RFWD2	3	p-S387-RFWD2 [nucleoplasm] (R-HSA-349450) RFWD2 [nucleoplasm] (R-HSA-349454) p-S387-RFWD2 [cytosol] (R-HSA-349439)	0.564	2
UniProt:P37173 TGFBR2	9	TGFBR2 Y470D [plasma membrane] (R-HSA-3640905) TGFBR2 E526Q [plasma membrane] (R-HSA-3645770) TGFBR2 D522N [plasma membrane] (R-HSA-3640907) TGFBR2 R528H [plasma membrane] (R-HSA-3640894) TGFBR2 R528C [plasma membrane] (R-HSA-3640899) TGFBR2 K128Afs3 [cytosol] (R-HSA-3642173) TGFBR2 K128Sfs35 [cytosol] (R-HSA-3642166) NEDD8-K556,K567-TGFBR2 [plasma membrane] (R-HSA-4332222) TGFBR2 [plasma membrane] (R-HSA-170842)	0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:P50454 SERPINH1	1	SERPINH1 [endoplasmic reticulum lumen] (R-HSA-2127480)	0.556	3
UniProt:P17612 PRKACA	4	PRKACA [mitochondrial matrix] (R-HSA-9838291) PRKACA [ciliary base] (R-HSA-5610402) PRKACA [nucleoplasm] (R-HSA-111936) PRKACA [cytosol] (R-HSA-57844)	0.556	3
UniProt:Q15131 CDK10			0.524	2
UniProt:Q15672 TWIST1	1	TWIST1 [nucleoplasm] (R-HSA-445442)	0.524	2
UniProt:Q8WVJ9 TWIST2	1	TWIST2 [nucleoplasm] (R-HSA-445444)	0.524	2
UniProt:Q16236 NFE2L2	13	p-S,T,S558-NFE2L2 [nucleoplasm] (R-HSA-9795736) p-S40, S344, S347- NFE2L2 [nucleoplasm] (R-HSA-9762050) p-S344, S347,T-NFE2L2 [nucleoplasm] (R-HSA-9762048) ub-p-S40, S335, S338- NFE2L2 [nucleoplasm] (R-HSA-9762058) ub-p-S335, S338,T-NFE2L2 [nucleoplasm] (R-HSA-9762055) ub-NFE2L2 [cytosol] (R-HSA-9758077) p-S40-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760018) p-S,T-18 AcK-NFE2L2 [nucleoplasm] (R-HSA-9760033) NFE2L2 [cytosol] (R-HSA-201566) p-S,T-NFE2L2 [cytosol] (R-HSA-8932311) p-S40-NFE2L2 [cytosol] (R-HSA-8932290) p-S,T-NFE2L2 [nucleoplasm] (R-HSA-9715110) p-S40-NFE2L2 [nucleoplasm] (R-HSA-9715109)	0.508	2
UniProt:Q8NHY2-1 COP1			0.462	2

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