Reactome | DHX9 binds DNA

DHX9 binds DNA

Stable Identifier

R-HSA-3134954

Type

Reaction [binding]

Species

Homo sapiens

Compartment

cytosol

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DHX9 binds CpG-B in human plasmacytoid dendritic cells (pDC). The DUF domain of DHX9 was shown to be essential for binding CpG-B [Kim T et al 2010].

Literature References

PubMed ID	Title	Journal	Year
20696886	Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells Kim, T, Pazhoor, S, Bao, M, Zhang, Z, Hanabuchi, S, Facchinetti, V, Bover, L, Plumas, J, Chaperot, L, Qin, J, Liu, YJ	Proc. Natl. Acad. Sci. U.S.A.	2010