Synthesis of VPU protein

Stable Identifier
R-HSA-3149433
Type
Reaction [omitted]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
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As the Rev protein accumulates, nuclear export of the singly and unspliced mRNAs is facilitated. These mRNAs express the Vif, Vpr, Vpu, Env proteins and the Gag and Gag-Pol polyproteins, respectively, and require Rev, which overcomes the restriction of nuclear export of intron-containing transcripts by accessing the CRM1 nuclear export pathway

Literature References
PubMed ID Title Journal Year
20082634 Alternative splicing: regulation of HIV-1 multiplication as a target for therapeutic action

Tazi, J, Bakkour, N, Marchand, V, Ayadi, L, Aboufirassi, A, Branlant, C

FEBS J. 2010
Participants
Participant Of
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease 526 HIV infection
Authored
Reviewed
Created