MRE11:dsDNA [cytosol]

Stable Identifier
R-HSA-3204308
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
23388631 DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

Kondo, T, Kobayashi, J, Saitoh, T, Maruyama, K, Ishii, KJ, Barber, GN, Komatsu, K, Akira, S, Kawai, T

Proc. Natl. Acad. Sci. U.S.A. 2013
Participants
components
Participant Of
output
This entity regulates
Positively
Inferred To
MRE11:dsDNA [cytosol] (Bos taurus)
MRE11:dsDNA [cytosol] (Caenorhabditis elegans)
MRE11:dsDNA [cytosol] (Canis familiaris)
MRE11:dsDNA [cytosol] (Danio rerio)
MRE11:dsDNA [cytosol] (Dictyostelium discoideum)
MRE11:dsDNA [cytosol] (Drosophila melanogaster)
MRE11:dsDNA [cytosol] (Mus musculus)
MRE11:dsDNA [cytosol] (Rattus norvegicus)
MRE11:dsDNA [cytosol] (Saccharomyces cerevisiae)
MRE11:dsDNA [cytosol] (Schizosaccharomyces pombe)
MRE11:dsDNA [cytosol] (Sus scrofa)
MRE11:dsDNA [cytosol] (Xenopus tropicalis)
Cite Us!