Reactome | A1CF [nucleoplasm]

A1CF [nucleoplasm]

Stable Identifier

R-HSA-3211440

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

APOBEC1 complementation factor, A1CF_HUMAN, ACF

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Locations in the PathwayBrowser for interactor UniProt:Q04864

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External Reference Information

External Reference

UniProt:Q9NQ94 A1CF

Gene Names

A1CF, ACF, ASP

Chain

chain:1-594

Reference Genes

BioGPS Gene:29974 A1CF

COSMIC (genes):A1CF A1CF

CTD Gene:29974 A1CF

dbSNP Gene:29974 A1CF

ENSEMBL:ENSG00000148584 A1CF

HGNC:24086 A1CF

KEGG Gene (Homo sapiens):29974 A1CF

Monarch:29974 A1CF

NCBI Gene:29974 A1CF

OMIM:618199 A1CF

UCSC:Q9NQ94 A1CF

Reference Transcript

Other Identifiers

0004610332

0004610438

11745515_a_at

11746909_a_at

16714348

220951_s_at

241547_at

29974

3289441

3289442

3289444

3289446

3289447

3289448

3289449

3289452

3289453

3289455

3289458

3289461

3289463

3289464

3289465

3289468

3289469

3289471

3289472

3289473

3289474

3289475

3289479

3289480

3289481

3289482

3289485

47095_at

57966_at

66976_r_at

7933640

A_23_P104224

A_24_P570378

GE55443

GO:0003674

GO:0003676

GO:0003723

GO:0003727

GO:0003729

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005783

GO:0006397

GO:0008150

GO:0016554

GO:0016556

GO:0030895

GO:0032991

GO:0034641

GO:0043226

GO:0050821

Hs.268821.0.A1_3p_at

ILMN_1779670

ILMN_1806310

ILMN_1883785

ILMN_1893846

ILMN_2383229

PH_hs_0000888

PH_hs_0013769

TC10001292.hg

TC10002643.hg

g7656852_3p_a_at

Participant Of

input

Binding of A1CF to stem-looped RNA

hasComponent

Inferred To

cpt1al [nucleoplasm] (Xenopus tropicalis)

a1cf [nucleoplasm] (Danio rerio)

A1CF [nucleoplasm] (Canis familiaris)

A1CF [nucleoplasm] (Gallus gallus)

A1CF [nucleoplasm] (Sus scrofa)

A1cf [nucleoplasm] (Mus musculus)

A1cf [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

XP_005269777.1, NP_620310.1, XP_005269775.1, NP_001185748.1, NP_620311.1, NP_001185747.1, NP_055391.2, NP_001185749.1

OpenTargets

ENSG00000148584

GeneCards

Q9NQ94

HPA

ENSG00000148584-A1CF

Ensembl

ENSP00000363113, ENSP00000282641, ENSG00000148584, ENSP00000363107, ENST00000395495, ENSP00000363109, ENST00000373995, ENSP00000363105, ENST00000373997, ENST00000374001, ENSP00000378873, ENST00000373993, ENST00000282641

PRO

Q9NQ94

HMDB Protein

HMDBP10774

PDB

2CPD

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13077 TRAF1	3	TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1 [cytosol] (R-HSA-5634163) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.718	6
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.556	3
UniProt:O76011 KRT34	1	KRT34 [cytosol] (R-HSA-6809608)	0.556	3
UniProt:Q58EX7 PKHG4			0.556	3
UniProt:Q04864 REL	2	REL [nucleoplasm] (R-HSA-1168585) REL [cytosol] (R-HSA-1168579)	0.556	3
UniProt:Q7L591-3 DOK3			0.556	3
UniProt:Q9UFD9 RIM3A			0.556	3
UniProt:Q8NCR6 SMRP1			0.556	3
UniProt:Q7Z3K3 POGZ			0.556	3
UniProt:Q16082 HSPB2			0.556	3
UniProt:Q8N6F8 MET27			0.556	3
UniProt:Q04637-9 EIF4G1			0.556	3
UniProt:Q5BKX5-3 C19ORF54			0.556	3
UniProt:Q96G42 KLD7B			0.556	3
UniProt:O43482 OIP5	1	OIP5 [nucleoplasm] (R-HSA-606286)	0.556	3
UniProt:Q15323 KRT31	1	KRT31 [cytosol] (R-HSA-6809616)	0.556	3
UniProt:A8MQ03 CRTP1			0.556	3
UniProt:Q16610 ECM1	2	ECM1 [platelet dense granule lumen] (R-HSA-8848880) ECM1 [extracellular region] (R-HSA-8848909)	0.556	3
UniProt:Q13643 FHL3			0.556	3

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