STK11 (LKB1) phosphorylates NUAK1

Stable Identifier
R-HSA-3222006
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

STK11 (LKB1) phosphorylates NUAK1 at threonine residue T211, resulting in NUAK1 activation (Hou et al. 2011).

Literature References
PubMed ID Title Journal Year
21317932 A new role of NUAK1: directly phosphorylating p53 and regulating cell proliferation

Hou, X, Liu, JE, Liu, W, Liu, CY, Liu, ZY, Sun, ZY

Oncogene 2011
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
protein serine/threonine kinase activity of TP53 Tetramer:STK11:NUAK1 [nucleoplasm]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed