Reactome: A Curated Pathway Database

DOT1L

Stable Identifier
R-HSA-3239030
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Histone-lysine N-methyltransferase, H3 lysine-79 specific, DOT1L_HUMAN, KMT4
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
DOT1L, KIAA1814, KMT4
Chain
chain:1-1739
Reference Genes
Reference Transcript
Other Identifiers
 0004760603  00310+2.1.1.43  11721397_at  11721398_a_at  11875
 16856699  214865_at  226201_at  231297_at  3816267
 3816268  3816269  3816274  3816279  3816280
 3816281  3816284  3816285  3816286  3816287
 3816288  3816289  3816290  3816291  3816293
 3816294  3816295  3816296  3816297  3816298
 3816299  3816300  3816302  3816306  3816307
 3816308  3816310  3816312  3816314  3816316
 3816317  3816327  3816328  3816329  3816330
 40525_at  43492_at  47137_at  71217  8024391
 84444  A_23_P101737  A_23_P408768  A_24_P936875  CCDS42460
 DOT1L  DOT1L-201  ENSG00000104885  ENSP00000381657  ENST00000398665
 EntrezGene:84444  GE53989  GO:0000077  GO:0000781  GO:0003674
 GO:0003677  GO:0005515  GO:0005575  GO:0005622  GO:0005623
 GO:0005634  GO:0005654  GO:0005694  GO:0006259  GO:0006281
 GO:0006342  GO:0006348  GO:0006464  GO:0006950  GO:0007049
 GO:0007165  GO:0008150  GO:0008168  GO:0008283  GO:0008284
 GO:0009058  GO:0016569  GO:0016740  GO:0018024  GO:0031151
 GO:0032200  GO:0032259  GO:0034641  GO:0034729  GO:0042054
 GO:0043226  GO:0043231  GO:0043234  GO:0045944  GO:0046425
 GO:0051276  GO:0051726  GO:2000677  HGNC:24948  Hs.156015.0.A1_3p_at
 Hs.173739.1.S1_3p_at  Hs.173739.2.S1_3p_at  Hs.713641  ILMN_1693559  IPR021169
 IPR025789  IPR029063  IPR030445  MIM:607375  NM_032482
 NP_115871  PF08123  PH_hs_0023520  TC19000049.hg  TC19001937.hg
 uc002lvb.4  UPI000002A839  XM_005259659  XM_005259660  XM_011528359
 XM_011528360  XM_011528361  XM_017027366  XP_005259716  XP_005259717
 XP_011526661  XP_011526662  XP_011526663  XP_016882855
Inferred To
Cross References
RefSeq
UCSC human
GeneCards
ZINC target
PRO
Orphanet
HMDB Protein
Interactors
Confidence Score Interactor Accession Interactor Name Evidence (IntAct)
0.723 P42568 AF9_HUMAN 5
0.677 Q03111 ENL_HUMAN 8
0.623 P55197 AF10_HUMAN 4
0.527 P55198 AF17_HUMAN 2