K63polyUb-STING [cytoplasmic vesicle membrane]

Stable Identifier
R-HSA-3248021
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytoplasmic vesicle membrane
Synonyms
MITA, TMEM173, ERIS
Icon
K63polyUb-STING [cytoplasmic vesicle membrane] icon
K63polyUb-STING [cytoplasmic vesicle membrane] icon
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q86WV6 STING1
Gene Names
STING1, ERIS, MITA, TMEM173
Chain
chain:1-379
Reference Genes
BioGPS Gene:340061 STING1
CTD Gene:340061 STING1
dbSNP Gene:340061 STING1
ENSEMBL:ENSG00000184584 TMEM173
ENSEMBL:ENSG00000288243 STING1
HGNC:27962 STING1
KEGG Gene (Homo sapiens):340061 STING1
Monarch:340061 STING1
NCBI Gene:340061 STING1
OMIM:612374 STING1
UCSC:Q86WV6 STING1
Reference Transcript
Other Identifiers
0001410398
11727044_a_at
17000650
224916_at
224929_at
2877991
2877992
2877993
2877994
2877995
2877998
2878000
2878002
2878003
2878004
2878005
2878006
2878007
2878008
2878009
340061
65817_at
8114536
A_23_P61371
GE88570
GO:0000045
GO:0000166
GO:0000421
GO:0002218
GO:0002230
GO:0002376
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005737
GO:0005739
GO:0005741
GO:0005768
GO:0005773
GO:0005776
GO:0005777
GO:0005783
GO:0005789
GO:0005794
GO:0005829
GO:0005886
GO:0006810
GO:0006914
GO:0006950
GO:0008134
GO:0008150
GO:0009056
GO:0009058
GO:0010468
GO:0016020
GO:0016021
GO:0016032
GO:0016192
GO:0016239
GO:0019899
GO:0019901
GO:0022607
GO:0030176
GO:0030659
GO:0030667
GO:0031323
GO:0031410
GO:0031625
GO:0032092
GO:0032479
GO:0032481
GO:0032608
GO:0033116
GO:0034641
GO:0035438
GO:0035458
GO:0042802
GO:0042803
GO:0043167
GO:0043226
GO:0043312
GO:0044403
GO:0045087
GO:0045944
GO:0048471
GO:0050727
GO:0051091
GO:0051259
GO:0051607
GO:0061507
GO:0061709
GO:0065003
GO:0071360
GO:0071407
GO:1990701
Hs.86347.1.A1_3p_at
Hs.86347.1.A2_3p_at
ILMN_1761447
ILMN_2145116
PH_hs_0033001
TC05001845.hg
Participant Of
hasComponent
Other forms of this molecule
K63polyUb-STING [endoplasmic reticulum membrane]
TMEM173 [endoplasmic reticulum membrane]
TMEM173 [plasma membrane]
TMEM173 [secretory granule membrane]
Inferred To
Sting1 [cytoplasmic vesicle membrane] (Mus musculus)
Sting1 [cytoplasmic vesicle membrane] (Rattus norvegicus)
STING1 [cytoplasmic vesicle membrane] (Bos taurus)
STING1 [cytoplasmic vesicle membrane] (Canis familiaris)
sting1 [cytoplasmic vesicle membrane] (Danio rerio)
sting1 [cytoplasmic vesicle membrane] (Xenopus tropicalis)
Modified Residues
Name
ubiquitinylated lysine (K63polyUb [cytosol]) at 150
Coordinate
150
Modification
K63polyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
OpenTargets
HPA
GeneCards
Ensembl
PRO
Orphanet
PDB
Interactors (31)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q86WV6 STING1  5 0.957 13
 UniProt:Q9UHD2 TBK1  5 0.862 8
 UniProt:Q7Z434-1 MAVS      0.78 7
 UniProt:Q7Z434 MAVS  2 0.71 7
 UniProt:P42226 STAT6  6 0.631 12
 UniProt:O15260 SURF4  5 0.623 3
 ChEBI:75947 CG(2'5')      0.558 2
 UniProt:P09914 IFIT1  1 0.558 3
 ChEBI:75948 CG(2'5')      0.558 2
 UniProt:P09913 IFIT2  1 0.558 3
 UniProt:Q9NZ01 TECR  1 0.556 3
 UniProt:Q9NV29 TM100      0.556 3
 UniProt:B2RUZ4 SMIM1      0.556 3
 UniProt:Q96HR9-2 REEP6      0.556 3
 UniProt:Q9Y342 PLLP      0.556 3
 UniProt:Q96DZ9-2 CMTM5      0.556 3
 UniProt:Q13190 STX5  5 0.556 3
 UniProt:O95214 LERL1      0.556 3
 UniProt:Q9BWQ6 YIPF2      0.556 3
 UniProt:P27958-PRO_0000037575      0.543 5
 UniProt:Q16666 IFI16  1 0.524 2
 UniProt:O95786-1 DDX58      0.524 2
 UniProt:P46977 STT3A  1 0.499 2
 UniProt:P39656 DDOST  3 0.499 2
 UniProt:O95470 SGPL1  1 0.499 2
 UniProt:O94822 LTN1  1 0.499 2
 UniProt:Q96A33 CCD47      0.499 2
 UniProt:P51617 IRAK1  14 0.499 2
 UniProt:Q96N66 MBOAT7  1 0.499 2
 UniProt:P43308 SSR2  1 0.482 4
 UniProt:Q99IB8-PRO_0000045601      0.463 5
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