pS-172,K48polyUb-TBK1 [cytosol]

Stable Identifier
R-HSA-3249397
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
pS-172,K48polyUb-TBK1 [cytosol] icon
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
TBK1, NAK
Chain
chain:1-729
Other Identifiers
11717931_at
11717932_at
16753498
218520_PM_at
218520_at
29110
3419850
3419853
3419854
3419855
3419856
3419858
3419861
3419865
3419866
3419867
3419870
3419871
3419872
3419873
3419874
3419875
3419877
3419879
3419881
3419882
3419883
3419884
3419885
3419887
3419889
3419890
3419891
63819_at
7956795
A_14_P113016
A_23_P44768
GO:0000166
GO:0002218
GO:0002376
GO:0002753
GO:0003676
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0006351
GO:0006355
GO:0006468
GO:0006914
GO:0006954
GO:0007249
GO:0009615
GO:0010468
GO:0010508
GO:0010629
GO:0010803
GO:0016239
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0018107
GO:0019903
GO:0023052
GO:0032479
GO:0032481
GO:0032727
GO:0032728
GO:0033138
GO:0036211
GO:0042802
GO:0043123
GO:0043226
GO:0043231
GO:0044565
GO:0045087
GO:0045944
GO:0050830
GO:0051219
GO:0051607
GO:0060337
GO:0060340
GO:0098542
GO:0098772
GO:0106310
GO:0140096
GO:0140374
GO:0140677
GO:1901214
GO:1902554
GO:1904417
HMNXSV003037647
ILMN_1739967
PH_hs_0025240
TC12000570.hg
g7019546_3p_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at 670
Coordinate
670
Modification
K48polyUb [cytosol]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Name
O-phospho-L-serine at 172
Coordinate
172
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
ZINC - Investigational
GeneCards
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
Interactors (46)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q92844 TANK  2 0.924 14
 UniProt:Q14653 IRF3  6 0.92 10
 UniProt:Q86WV6 STING1  5 0.899 9
 UniProt:Q96CV9 OPTN  5 0.898 16
 UniProt:A7MCY6 TBKB1      0.858 9
 UniProt:Q12933 TRAF2  5 0.857 7
 UniProt:P0DTD1-PRO_0000449630 REP      0.822 6
 UniProt:Q9H6S1 AZI2      0.813 7
 UniProt:Q13137 CACO2      0.748 7
 UniProt:Q7Z434 MAVS  2 0.723 6
 UniProt:P40222 TXLNA  1 0.708 6
 UniProt:P59596 M  10 0.702 5
 UniProt:Q9Y6K9 IKBKG  12 0.702 4
 UniProt:Q13114 TRAF3  4 0.688 4
 UniProt:Q8IUC6 TICAM1  4 0.688 3
 UniProt:P0DTC5 M  10 0.681 10
 UniProt:Q14164 IKBKE  4 0.669 5
 UniProt:Q6DT37 MRCKG      0.623 3
 UniProt:Q9UHD2 TBK1  4 0.609 2
 UniProt:P08238 HSP90AB1  6 0.589 3
 UniProt:Q60803  3 0.589 2
 UniProt:P42226 STAT6  6 0.577 7
 UniProt:P27958-PRO_0000037573      0.571 4
 UniProt:P04406 GAPDH  1 0.564 2
 UniProt:W5VXH5 W5VXH5      0.556 3
 UniProt:O75558 STX11      0.547 2
 UniProt:Q9H492 MAP1LC3A  3 0.544 2
 UniProt:Q05127 VP35      0.544 2
 UniProt:Q9GZQ8 MAP1LC3B  3 0.544 2
 UniProt:O95801 TTC4      0.537 5
 UniProt:I6W9F2 I6W9F2      0.537 6
 UniProt:P27958-PRO_0000037572      0.524 2
 UniProt:K7Y1A2 K7Y1A2      0.524 2
 UniProt:Q92985 IRF7  5 0.508 2
 UniProt:CYorf15B CY15B      0.499 2
 UniProt:Q9Y6W8 ICOS  1 0.499 5
 UniProt:Q9UKV8 AGO2  2 0.499 2
 UniProt:Q9NVV4 PAPD1      0.499 2
 UniProt:Q86YT6 MIB1  1 0.499 2
 UniProt:Q7Z3C6 ATG9A  1 0.499 2
 UniProt:Q8BHN1 TXLNG      0.499 2
 UniProt:Q96AX9 MIB2  1 0.499 2
 UniProt:O14730 RIOK3  1 0.499 3
 UniProt:O41932 O41932      0.488 4
 UniProt:A0A0B5AC19 NSS      0.463 4
 UniProt:P0DTD2 9b  3 0.463 2
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