Reactome | KAT7 [nucleoplasm]

KAT7 [nucleoplasm]

Stable Identifier

R-HSA-3321823

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Histone acetyltransferase KAT7, KAT7_HUMAN, HBO1, MYST2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O95251 KAT7

Gene Names

KAT7, HBO1, HBOa, MYST2

Chain

chain:1-611

Reference Genes

BioGPS Gene:11143 KAT7

COSMIC (genes):KAT7 KAT7

CTD Gene:11143 KAT7

dbSNP Gene:11143 KAT7

ENSEMBL:ENSG00000136504 KAT7

ENSEMBL_homo_sapiens_GENE:ENSG00000136504.15 KAT7

HGNC:17016 KAT7

KEGG Gene (Homo sapiens):11143 KAT7

Monarch:11143 KAT7

NCBI Gene:11143 KAT7

OMIM:609880 KAT7

UCSC:O95251 KAT7

Reference Transcript

Other Identifiers

11143

11732117_s_at

11752292_s_at

11753890_a_at

11757691_a_at

16835615

18671469

18671471

18671472

18671473

18671474

18671475

18671479

18671480

18671481

18671483

18671485

18671487

18671489

18671490

200049_PM_at

200049_at

2346621

34231_at

3725783

3725784

3725785

3725790

3725795

3725796

3725800

3725801

3725802

3725803

3725806

3725808

3725809

3725811

3725813

3725815

3725818

3725819

3725820

3725821

3725822

3726038

3726040

3726042

3726044

3726045

3726046

3726048

4014908

4014911

4014913

4014915

4014916

65271_s_at

7892771

7892967

7893240

7893682

7893834

7893886

7894226

7894635

7894648

7895397

7895599

7895971

7896231

7896499

7896522

7896534

7896546

7896600

8008213

84317_at

A_14_P108562

A_23_P152818

GE58435

GO:0000123

GO:0000775

GO:0001558

GO:0001779

GO:0002376

GO:0003677

GO:0003688

GO:0003712

GO:0003824

GO:0004402

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005829

GO:0006260

GO:0006275

GO:0006281

GO:0006325

GO:0006338

GO:0006351

GO:0006355

GO:0006974

GO:0008270

GO:0010485

GO:0016573

GO:0016740

GO:0016746

GO:0018393

GO:0023052

GO:0030154

GO:0030174

GO:0031098

GO:0032786

GO:0036211

GO:0036408

GO:0036409

GO:0043226

GO:0043994

GO:0043995

GO:0043996

GO:0043997

GO:0044016

GO:0045740

GO:0045815

GO:0045892

GO:0045944

GO:0046872

GO:0048856

GO:0051726

GO:0072708

GO:0072710

GO:0072716

GO:0072720

GO:0072739

GO:0090734

GO:0140096

GO:0140110

GO:0140889

GO:1900182

GO:1902035

GO:2000278

GO:2000819

HMNXSV003000615

HMNXSV003010227

ILMN_1798187

PH_hs_0027598

TC17000648.hg

g5901961_3p_at

p7414

Participates

as a component of

KAT7:ING4,5 dimers:MEAF6:PHF17,(15,16) [nucleoplasm] (Homo sapiens)

Inferred To

Homologues of KAT7 [nucleoplasm] (Dictyostelium discoideum)

KAT7 [nucleoplasm] (Bos taurus)

KAT7 [nucleoplasm] (Caenorhabditis elegans)

KAT7 [nucleoplasm] (Canis familiaris)

KAT7 [nucleoplasm] (Dictyostelium discoideum)

KAT7 [nucleoplasm] (Mus musculus)

KAT7 [nucleoplasm] (Rattus norvegicus)

KAT7 [nucleoplasm] (Schizosaccharomyces pombe)

KAT7 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_001186085.1, NP_001186086.1, NP_001186084.1, NP_008998.1, NP_001186087.1

Guide to Pharmacology - Targets

2667

OpenTargets

ENSG00000136504

GeneCards

O95251

HPA

ENSG00000136504-KAT7

Ensembl

ENST00000259021, ENST00000706506, ENSG00000136504, ENSP00000424577, ENSP00000413415, ENSP00000423385, ENST00000510819, ENST00000424009, ENSP00000259021, ENST00000454930, ENST00000509773, ENSP00000516419, ENSP00000398961

PRO

O95251

Pharos - Targets

O95251

HMDB Protein

HMDBP11580

PDB

7D0Q, 7D0O, 7D0S, 5GK9, 6MAK, 6MAJ, 7D0R, 7D0P

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P08670 VIM	11	VIM(2-85) [cytosol] (R-HSA-350264) VIM(86-466) [cytosol] (R-HSA-350294) VIM(430-466) [cytosol] (R-HSA-350316) VIM(2-429) [cytosol] (R-HSA-350317) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-259) [cytosol] (R-HSA-350323) VIM [cytosol] (R-HSA-201600) Vimentin [late endosome lumen] (R-HSA-9660019) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [cytosol] (R-HSA-9646687) Vimentin [lysosomal lumen] (R-HSA-9659977)	0.747	4
UniProt:P53350 PLK1	4	PLK1 [nucleoplasm] (R-HSA-156720) p-T210-PLK1 [cytosol] (R-HSA-3000318) p-T210-PLK1 [nucleoplasm] (R-HSA-3002800) PLK1 [cytosol] (R-HSA-164603)	0.671	6
UniProt:P10275 AR	4	PolyUb-AR [nucleoplasm] (R-HSA-6782984) monoSUMO1-K386,520-AR [nucleoplasm] (R-HSA-4090320) AR [nucleoplasm] (R-HSA-446174) AR [cytosol] (R-HSA-5618082)	0.593	5
UniProt:Q96EZ8 MCRS1	1	MCRS1 [nucleoplasm] (R-HSA-3321849)	0.556	3
UniProt:Q99728 BARD1	13	BARD1 G623E [nucleoplasm] (R-HSA-9699135) BARD1 C71Y [nucleoplasm] (R-HSA-9700808) BARD1 C53W [nucleoplasm] (R-HSA-9700807) BARD1 G623W [nucleoplasm] (R-HSA-9699148) BARD1 W34R [nucleoplasm] (R-HSA-9699166) BARD1 H68Y [nucleoplasm] (R-HSA-9699151) BARD1 L44R [nucleoplasm] (R-HSA-9699126) BARD1 C50G [nucleoplasm] (R-HSA-9699137) BARD1 C83G [nucleoplasm] (R-HSA-9699139) K6PolyUb-BARD1 [nucleoplasm] (R-HSA-9701024) K6PolyUb,p-T714,T734-BARD1 [nucleoplasm] (R-HSA-9707286) p-T714,T734-BARD1 [nucleoplasm] (R-HSA-5659846) BARD1 [nucleoplasm] (R-HSA-5659775)	0.508	2