Reactome | EPC1 [nucleoplasm]

EPC1 [nucleoplasm]

Stable Identifier

R-HSA-3321978

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Enhancer of polycomb homolog 1, EPC1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9H2F5 EPC1

Gene Names

EPC1

Chain

chain:1-836

Reference Genes

BioGPS Gene:80314 EPC1

COSMIC (genes):EPC1 EPC1

CTD Gene:80314 EPC1

dbSNP Gene:80314 EPC1

ENSEMBL:ENSG00000120616 EPC1

HGNC:19876 EPC1

KEGG:hsa:80314 EPC1

Monarch:80314 EPC1

NCBI Gene:80314 EPC1

OMIM:610999 EPC1

UCSC:Q9H2F5 EPC1

Reference Transcript

Participates

as a component of

as an input of

E2F6:TFDP1 binds EPC1 (Homo sapiens)

Inferred To

epc1b [nucleoplasm] (Danio rerio)

epc1 [nucleoplasm] (Xenopus tropicalis)

EPC1 [nucleoplasm] (Bos taurus)

EPC1 [nucleoplasm] (Canis familiaris)

EPC1 [nucleoplasm] (Dictyostelium discoideum)

EPC1 [nucleoplasm] (Gallus gallus)

EPC1 [nucleoplasm] (Sus scrofa)

E(Pc) [nucleoplasm] (Drosophila melanogaster)

epc-1 [nucleoplasm] (Caenorhabditis elegans)

Epc1 [nucleoplasm] (Mus musculus)

Epc1 [nucleoplasm] (Rattus norvegicus)

Cross References

RefSeq

NP_001269320.1, NP_001258933.1, NP_001258948.1, NP_079485.1

OpenTargets

ENSG00000120616

ENSEMBL

ENSP00000263062, ENSP00000318559, ENST00000375110, ENSP00000364251, ENST00000263062, ENST00000319778, ENSG00000120616

HPA

ENSG00000120616-EPC1

GeneCards

EPC1

PRO

Q9H2F5

Pharos - Targets

Q9H2F5

GlyGen

Q9H2F5

PDB

8XVT, 9C57, 9C62, 6NFX, 9C6N, 8QR1, 8XVG

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y230 RUVBL2	1	RUVBL2 [nucleoplasm] (R-HSA-418321)	0.788	7
UniProt:Q9Y265 RUVBL1	1	RUVBL1 [nucleoplasm] (R-HSA-418323)	0.725	7
UniProt:Q9NV56 MRGBP	1	MRGBP [nucleoplasm] (R-HSA-3322953)	0.725	7
UniProt:Q6NUQ1 RINT1	1	RINT1 [cytosol] (R-HSA-6810991)	0.696	5
UniProt:Q9HAF1 MEAF6	1	MEAF6 [nucleoplasm] (R-HSA-3318448)	0.643	5
UniProt:Q15014 MORF4L2	1	MORF4L2 [nucleoplasm] (R-HSA-3322945)	0.643	5
UniProt:Q9UBU8 MORF4L1	1	MORF4L1 [nucleoplasm] (R-HSA-3321982)	0.643	6
UniProt:P19012 KRT15	1	KRT15 [cytosol] (R-HSA-6809589)	0.556	3
UniProt:P52294 KPNA1	2	KPNA1 [cytosol] (R-HSA-180612) KPNA1 [nucleoplasm] (R-HSA-188865)	0.527	2
UniProt:O96019 ACTL6A	1	ACTL6A [nucleoplasm] (R-HSA-2980912)	0.527	4
UniProt:O95619 YEATS4	1	YEATS4 [nucleoplasm] (R-HSA-3322940)	0.527	4
UniProt:Q15906 VPS72	1	VPS72 [nucleoplasm] (R-HSA-3321992)	0.527	3
UniProt:Q6PIV2 FOXR1			0.527	2
UniProt:Q96A08 H2BC1	9	HIST1H2BA [nucleoplasm] (R-HSA-181916) AcK22-HIST1H2BA [nucleoplasm] (R-HSA-4568647) AcK17-HIST1H2BA [nucleoplasm] (R-HSA-4568631) AcK14-HIST1H2BA [nucleoplasm] (R-HSA-4568615) AcK7-HIST1H2BA [nucleoplasm] (R-HSA-4568624) Ub-122-HIST1H2BA [nucleoplasm] (R-HSA-3364020) HIST1H2BA [extracellular region] (R-HSA-977582) AcK-HIST1H2BA [nucleoplasm] (R-HSA-4549263) Ub-HIST1H2BA [nucleoplasm] (R-HSA-6782561)	0.527	4
UniProt:P0C0S5 H2AZ1	1	H2AFZ [extracellular region] (R-HSA-977575)	0.527	5
UniProt:Q92993 KAT5	1	KAT5 [nucleoplasm] (R-HSA-3321979)	0.527	5
UniProt:Q9NPF5 DMAP1	1	DMAP1 [nucleoplasm] (R-HSA-212166)	0.527	5
UniProt:Q05BQ5 MBTD1			0.525	6
UniProt:Q9H0E9 BRD8	1	BRD8 [nucleoplasm] (R-HSA-3321977)	0.499	5
UniProt:P01106 MYC	2	MYC [nucleoplasm] (R-HSA-188379) PolyUb-MYC [nucleoplasm] (R-HSA-6783169)	0.483	2
UniProt:Q86VZ6 JAZF1			0.483	3

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