Reactome: A Curated Pathway Database

XIAP dissociates from ub-TLE

Stable Identifier
R-HSA-3322434
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

After ubiquitinating TLE, XIAP presumably dissociates. The model proposed by Hanson et al suggests the existence of an as-yet unidentified deubiquitinase that removes the ubiquitin from TLE to allow it to rebind to TCF/LEF.

Literature References
PubMed ID Title Journal Year
Participants
Participant Of
Orthologous Events