Reactome | YEATS4 [nucleoplasm]

YEATS4 [nucleoplasm]

Stable Identifier

R-HSA-3322940

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

YEATS domain-containing protein 4, YETS4_HUMAN, GAS41

Locations in the PathwayBrowser for interactor UniProt:Q9Y265

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Homo sapiens)
      - Activation of the TFAP2 (AP-2) family of transcription factors (Homo sapiens)
        
        TFAP2B homodimer binds YEATS4 (Homo sapiens)
        
        YEATS4 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:O95619 YEATS4

Gene Names

YEATS4, GAS41

Chain

chain:1-227

Reference Genes

BioGPS Gene:8089 YEATS4

COSMIC (genes):YEATS4 YEATS4

CTD Gene:8089 YEATS4

dbSNP Gene:8089 YEATS4

ENSEMBL:ENSG00000127337 YEATS4

HGNC:24859 YEATS4

KEGG Gene (Homo sapiens):8089 YEATS4

Monarch:8089 YEATS4

NCBI Gene:8089 YEATS4

OMIM:602116 YEATS4

UCSC:O95619 YEATS4

Reference Transcript

Other Identifiers

0005130154

11720833_at

16753923

218911_at

3421524

3421525

3421526

3421527

3421531

3421533

3421534

3421536

3421537

3421542

3421543

3421544

64121_at

7957032

8089

A_23_P87591

GE59283

GO:0000278

GO:0003674

GO:0005198

GO:0005200

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005635

GO:0005654

GO:0006325

GO:0006355

GO:0006464

GO:0007010

GO:0007049

GO:0008022

GO:0008150

GO:0009058

GO:0016363

GO:0031965

GO:0032991

GO:0034641

GO:0035267

GO:0040007

GO:0040008

GO:0042393

GO:0043226

GO:0043967

GO:0043968

GO:0045893

GO:0045944

GO:0051276

GO:0070577

GO:0140030

HMNXSV003030757

ILMN_1801387

PH_hs_0000445

TC12000612.hg

g5729837_3p_at

Participates

as a component of

as an input of

TFAP2B homodimer binds YEATS4 (Homo sapiens)

Inferred To

yaf9 [nucleoplasm] (Schizosaccharomyces pombe)

YAF9 [nucleoplasm] (Saccharomyces cerevisiae)

gfl-1 [nucleoplasm] (Caenorhabditis elegans)

Gas41 [nucleoplasm] (Drosophila melanogaster)

yeats4 [nucleoplasm] (Danio rerio)

yeats4 [nucleoplasm] (Xenopus tropicalis)

YEATS4 [nucleoplasm] (Bos taurus)

YEATS4 [nucleoplasm] (Canis familiaris)

YEATS4 [nucleoplasm] (Dictyostelium discoideum)

YEATS4 [nucleoplasm] (Plasmodium falciparum)

Yeats4 [nucleoplasm] (Mus musculus)

Yeats4 [nucleoplasm] (Rattus norvegicus)

GAS41 [nucleoplasm] (Gallus gallus)

Cross References

RefSeq

NP_001287879.1, NP_006521.1

OpenTargets

ENSG00000127337

GeneCards

O95619

HPA

ENSG00000127337-YEATS4

Ensembl

ENSG00000127337, ENST00000247843, ENSP00000247843

PRO

O95619

PDB

5VNA, 5Y8V, 5VNB, 5XTZ

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NV56 MRGBP	1	MRGBP [nucleoplasm] (R-HSA-3322953)	0.788	5
UniProt:O43257 ZNHI1			0.725	4
UniProt:Q9Y265 RUVBL1	1	RUVBL1 [nucleoplasm] (R-HSA-418323)	0.643	3
UniProt:Q05BQ5 MBTD1			0.643	4
UniProt:Q9Y230 RUVBL2	1	RUVBL2 [nucleoplasm] (R-HSA-418321)	0.643	3
UniProt:Q15906 VPS72	1	VPS72 [nucleoplasm] (R-HSA-3321992)	0.643	3
UniProt:Q8NFD2 ANKK1			0.556	3
UniProt:P09493-10 TPM1			0.556	3
UniProt:O75410 TACC1			0.543	6
UniProt:Q9NXR8 ING3	1	ING3 [nucleoplasm] (R-HSA-3215168)	0.527	2
UniProt:Q9NPF5 DMAP1	1	DMAP1 [nucleoplasm] (R-HSA-212166)	0.527	2
UniProt:Q6ZRS2-2 SRCAP			0.527	2
UniProt:Q9H0E9-2 BRD8			0.527	2
UniProt:Q9Y4A5-2 TRRAP			0.527	2
UniProt:Q52LR7 EPC2			0.527	2
UniProt:Q6PIV2 FOXR1			0.527	2
UniProt:Q92993-2 KAT5			0.527	2
UniProt:Q66LE6 PPP2R2D	1	PPP2R2D [nucleoplasm] (R-HSA-2160962)	0.527	2
UniProt:O96019 ACTL6A	1	ACTL6A [nucleoplasm] (R-HSA-2980912)	0.527	5
UniProt:Q9H2F5-2 EPC1			0.527	2
UniProt:Q9UBU8-2 MORF4L1			0.527	2
UniProt:P61244 MAX	1	MAX [nucleoplasm] (R-HSA-3006627)	0.508	2
UniProt:Q9BTT0 AN32E			0.499	3

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