Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
TRRAP [nucleoplasm]
Stable Identifier
R-HSA-3322951
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Transformation/transcription domain-associated protein, TRRAP_HUMAN
Locations in the PathwayBrowser
Expand all
Chromatin organization (Homo sapiens)
Chromatin modifying enzymes (Homo sapiens)
HATs acetylate histones (Homo sapiens)
KAT2 complexes acetylate histone H3 (Homo sapiens)
KAT2A,B complexes [nucleoplasm] (Homo sapiens)
STAGA complex [nucleoplasm] (Homo sapiens)
TRRAP [nucleoplasm] (Homo sapiens)
NuA4 complex acetylates histone H2A, HIST1H4 (Homo sapiens)
NuA4 [nucleoplasm] (Homo sapiens)
TRRAP [nucleoplasm] (Homo sapiens)
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Deubiquitination (Homo sapiens)
Ub-specific processing proteases (Homo sapiens)
USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
USP3, SAGA complex [nucleoplasm] (Homo sapiens)
SAGA [nucleoplasm] (Homo sapiens)
TRRAP [nucleoplasm] (Homo sapiens)
USP3,SAGA:Histone H2A,Histone H2B [nucleoplasm] (Homo sapiens)
USP3, SAGA complex [nucleoplasm] (Homo sapiens)
SAGA [nucleoplasm] (Homo sapiens)
TRRAP [nucleoplasm] (Homo sapiens)
USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
USP3, SAGA complex [nucleoplasm] (Homo sapiens)
SAGA [nucleoplasm] (Homo sapiens)
TRRAP [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
TCF dependent signaling in response to WNT (Homo sapiens)
Formation of the beta-catenin:TCF transactivating complex (Homo sapiens)
Beta-catenin recruits TRRAP/KAT5 HAT components (Homo sapiens)
TCF/LEF:CTNNB1:RUVBL1:TRRAP:KAT5 [nucleoplasm] (Homo sapiens)
TRRAP [nucleoplasm] (Homo sapiens)
TRRAP [nucleoplasm] (Homo sapiens)
KAT5 HAT complex acetylates TCF4 gene at histone H4 (Homo sapiens)
TCF/LEF:CTNNB1:RUVBL1:TRRAP:KAT5 [nucleoplasm] (Homo sapiens)
TRRAP [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9Y4A5 TRRAP
Gene Names
TRRAP, PAF400
Chain
initiator methionine:1, chain:2-3859
Reference Genes
BioGPS Gene:8295 TRRAP
COSMIC (genes):TRRAP TRRAP
CTD Gene:8295 TRRAP
dbSNP Gene:8295 TRRAP
ENSEMBL:ENSG00000196367 TRRAP
HGNC:12347 TRRAP
KEGG Gene (Homo sapiens):8295 TRRAP
Monarch:8295 TRRAP
NCBI Gene:8295 TRRAP
OMIM:603015 TRRAP
UCSC:Q9Y4A5 TRRAP
Reference Transcript
RefSeq:NM_001244580.1 TRRAP
RefSeq:NM_003496.3 TRRAP
Other Identifiers
0006860301
11719900_a_at
11719901_s_at
17048754
202642_s_at
214908_s_at
3014412
3014413
3014414
3014415
3014418
3014419
3014420
3014421
3014422
3014423
3014424
3014425
3014426
3014429
3014432
3014433
3014434
3014435
3014436
3014437
3014438
3014439
3014440
3014441
3014443
3014444
3014445
3014447
3014448
3014449
3014451
3014452
3014453
3014454
3014456
3014457
3014458
3014460
3014461
3014462
3014463
3014464
3014465
3014466
3014468
3014470
3014471
3014473
3014474
3014476
3014477
3014478
3014479
3014481
3014482
3014484
3014486
3014487
3014488
3014491
3014492
3014493
3014494
3014496
3014499
3014501
3014502
3014505
3014506
3014507
3014510
3014512
3014513
3014514
3014515
3014519
3014520
3014528
3014529
3014530
3014531
3014532
3014534
3014535
3014536
33810_at
8134470
8295
A_23_P94053
GE61279
GO:0000123
GO:0000124
GO:0000125
GO:0000228
GO:0000812
GO:0003674
GO:0003712
GO:0005515
GO:0005575
GO:0005622
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005794
GO:0006259
GO:0006281
GO:0006325
GO:0006355
GO:0006464
GO:0006950
GO:0008150
GO:0009058
GO:0016310
GO:0016573
GO:0016578
GO:0016579
GO:0022607
GO:0030914
GO:0032991
GO:0033276
GO:0034641
GO:0035267
GO:0043226
GO:0043967
GO:0043968
GO:0051276
GO:0065003
GO:1904837
Hs.247755.0.S1_3p_s_at
ILMN_1660368
PH_hs_0011978
TC07003396.hg
g4507690_3p_a_at
Participant Of
hasComponent
LEF:CTNNB1:RUVBL1:TRRAP:KAT5 [nucleoplasm]
NuA4 [nucleoplasm]
SAGA [nucleoplasm]
STAGA complex [nucleoplasm]
TCF/LEF:CTNNB1:RUVBL1:TRRAP:KAT5 [nucleoplasm]
input
Beta-catenin recruits TRRAP/KAT5 HAT components
Inferred To
TRA1 [nucleoplasm] (Saccharomyces cerevisiae)
Ghost homologue of TRRAP [nucleoplasm] (Mus musculus)
Ghost homologue of TRRAP [nucleoplasm] (Rattus norvegicus)
tra1 [nucleoplasm] (Schizosaccharomyces pombe)
Nipped-A [nucleoplasm] (Drosophila melanogaster)
TRRAP [nucleoplasm] (Bos taurus)
TRRAP [nucleoplasm] (Canis familiaris)
TRRAP [nucleoplasm] (Gallus gallus)
TRRAP [nucleoplasm] (Sus scrofa)
trrap [nucleoplasm] (Danio rerio)
trrap [nucleoplasm] (Xenopus tropicalis)
Cross References
RefSeq
NP_003487.1
,
NP_001231509.1
OpenTargets
ENSG00000196367
HPA
ENSG00000196367-TRRAP
GeneCards
Q9Y4A5
Ensembl
ENSG00000196367
,
ENSP00000347733
,
ENST00000355540
,
ENSP00000352925
,
ENST00000359863
PRO
Q9Y4A5
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P01106 MYC
2
PolyUb-MYC [nucleoplasm]
(R-HSA-6783169)
MYC [nucleoplasm]
(R-HSA-188379)
0.793
5
UniProt:Q92830 KAT2A
1
KAT2A [nucleoplasm]
(R-HSA-3006516)
0.69
5
UniProt:O15265 ATXN7
2
ATXN7 [cytosol]
(R-HSA-201591)
ATXN7 [nucleoplasm]
(R-HSA-8869458)
0.662
7
UniProt:Q9NV56 MRGBP
1
MRGBP [nucleoplasm]
(R-HSA-3322953)
0.662
5
UniProt:O96019 ACTL6A
1
ACTL6A [nucleoplasm]
(R-HSA-2980912)
0.564
5
UniProt:P49336 CDK8
1
CDK8 [nucleoplasm]
(R-HSA-212440)
0.558
4
UniProt:Q96ES7 SGF29
1
SGF29 [nucleoplasm]
(R-HSA-3662279)
0.527
2
UniProt:Q15906 VPS72
1
VPS72 [nucleoplasm]
(R-HSA-3321992)
0.527
2
UniProt:O43156 TTI1
0.527
2
UniProt:Q9Y265 RUVBL1
1
RUVBL1 [nucleoplasm]
(R-HSA-418323)
0.527
3
© 2021
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text