Reactome | TADA3 [nucleoplasm]

TADA3 [nucleoplasm]

Stable Identifier

R-HSA-3322966

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcriptional adapter 3, TADA3_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Deubiquitination (Homo sapiens)
    - Ub-specific processing proteases (Homo sapiens)
      - USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
        
        USP3, SAGA complex [nucleoplasm] (Homo sapiens)
        
        SAGA [nucleoplasm] (Homo sapiens)
        
        TADA3 [nucleoplasm] (Homo sapiens)
        
        USP3,SAGA:Histone H2A,Histone H2B [nucleoplasm] (Homo sapiens)
        
        USP3, SAGA complex [nucleoplasm] (Homo sapiens)
        
        SAGA [nucleoplasm] (Homo sapiens)
        
        TADA3 [nucleoplasm] (Homo sapiens)
        
        USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
        
        USP3, SAGA complex [nucleoplasm] (Homo sapiens)
        
        SAGA [nucleoplasm] (Homo sapiens)
        
        TADA3 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:O75528 TADA3

Gene Names

TADA3, ADA3, TADA3L

Chain

chain:1-432

Reference Genes

BioGPS Gene:10474 TADA3

COSMIC (genes):TADA3 TADA3

CTD Gene:10474 TADA3

dbSNP Gene:10474 TADA3

ENSEMBL:ENSG00000171148 TADA3

HGNC:19422 TADA3

KEGG Gene (Homo sapiens):10474 TADA3

Monarch:10474 TADA3

NCBI Gene:10474 TADA3

OMIM:602945 TADA3

UCSC:O75528 TADA3

Reference Transcript

Other Identifiers

0000510537

0001340452

0002570152

10474

11719001_a_at

11736036_a_at

11736037_x_at

11736038_x_at

11748818_x_at

16950569

211221_at

215273_s_at

2662357

2662358

2662361

2662362

2662363

2662364

2662365

2662366

2662367

2662373

2662374

2662376

2662377

2662378

2662379

2662381

35749_at

8085220

A_23_P109821

A_23_P305016

GE56484

GO:0000124

GO:0000278

GO:0001932

GO:0003674

GO:0003713

GO:0004402

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005671

GO:0005856

GO:0006357

GO:0006464

GO:0007049

GO:0007165

GO:0008134

GO:0008150

GO:0009058

GO:0010628

GO:0016579

GO:0016746

GO:0016922

GO:0019904

GO:0030374

GO:0030520

GO:0030914

GO:0031063

GO:0031647

GO:0032991

GO:0033276

GO:0034641

GO:0043226

GO:0043966

GO:0043967

GO:0045893

GO:0051276

GO:0072686

GO:0090043

Hs.158196.3.S1_3p_a_at

ILMN_1674866

ILMN_1770141

ILMN_1792176

PH_hs_0024391

TC03001150.hg

g5911971_3p_at

g5911971_3p_x_at

Participant Of

hasComponent

Inferred To

Tada3 [nucleoplasm] (Mus musculus)

Tada3 [nucleoplasm] (Rattus norvegicus)

TADA3 [nucleoplasm] (Bos taurus)

TADA3 [nucleoplasm] (Canis familiaris)

TADA3 [nucleoplasm] (Sus scrofa)

ngg1 [nucleoplasm] (Schizosaccharomyces pombe)

tada3 [nucleoplasm] (Danio rerio)

tada3 [nucleoplasm] (Xenopus tropicalis)

Ada3 [nucleoplasm] (Drosophila melanogaster)

NGG1 [nucleoplasm] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_006345.1, NP_001265199.1, NP_597814.1

OpenTargets

ENSG00000171148

HPA

ENSG00000171148-TADA3

GeneCards

O75528

Ensembl

ENST00000440161, ENST00000343450, ENST00000301964, ENSP00000307684, ENSP00000393471, ENSG00000171148, ENSP00000343649

PRO

O75528

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92831 KAT2B	1	KAT2B [nucleoplasm] (R-HSA-352430)	0.643	3
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.643	3
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.556	3
UniProt:Q92830 KAT2A	1	KAT2A [nucleoplasm] (R-HSA-3006516)	0.527	2
UniProt:Q8N2W9 PIAS4	2	SUMO1-K35-PIAS4 [nucleoplasm] (R-HSA-3968415) PIAS4 [nucleoplasm] (R-HSA-2993789)	0.508	2
UniProt:Q9NY61 AATF	1	AATF [cytosol] (R-HSA-205071)	0.508	2