Reactome | TADA3 [nucleoplasm]

TADA3 [nucleoplasm]

Stable Identifier

R-HSA-3322966

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcriptional adapter 3, TADA3_HUMAN

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Homo sapiens)

- Post-translational protein modification (Homo sapiens)
  - Deubiquitination (Homo sapiens)
    - Ub-specific processing proteases (Homo sapiens)
      - USP3,SAGA deubiquitinate Histone H2A,H2B (Homo sapiens)
        
        USP3, SAGA complex [nucleoplasm] (Homo sapiens)
        
        SAGA [nucleoplasm] (Homo sapiens)
        
        TADA3 [nucleoplasm] (Homo sapiens)
        
        USP3,SAGA:Histone H2A,Histone H2B [nucleoplasm] (Homo sapiens)
        
        USP3, SAGA complex [nucleoplasm] (Homo sapiens)
        
        SAGA [nucleoplasm] (Homo sapiens)
        
        TADA3 [nucleoplasm] (Homo sapiens)
        
        USP3,SAGA:Ub-histone H2A, Ub-histone H2B [nucleoplasm] (Homo sapiens)
        
        USP3, SAGA complex [nucleoplasm] (Homo sapiens)
        
        SAGA [nucleoplasm] (Homo sapiens)
        
        TADA3 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:O75528 TADA3

Gene Names

TADA3, ADA3, TADA3L

Chain

chain:1-432

Reference Genes

BioGPS Gene:10474 TADA3

COSMIC (genes):TADA3 TADA3

CTD Gene:10474 TADA3

dbSNP Gene:10474 TADA3

ENSEMBL:ENSG00000171148 TADA3

ENSEMBL:ENSG00000171148.14 TADA3

HGNC:19422 TADA3

KEGG Gene (Homo sapiens):10474 TADA3

Monarch:10474 TADA3

NCBI Gene:10474 TADA3

OMIM:602945 TADA3

UCSC:O75528 TADA3

Reference Transcript

Other Identifiers

10474

11719001_a_at

11736036_a_at

11736037_x_at

11736038_x_at

11748818_x_at

16950569

211221_PM_at

211221_at

215273_PM_s_at

215273_s_at

2662357

2662358

2662361

2662362

2662363

2662364

2662365

2662366

2662367

2662373

2662374

2662376

2662377

2662378

2662379

2662381

35749_at

8085220

A_23_P109821

A_23_P305016

GE56484

GO:0000124

GO:0000278

GO:0001932

GO:0003713

GO:0005515

GO:0005634

GO:0005654

GO:0005856

GO:0006281

GO:0006282

GO:0006325

GO:0006351

GO:0006355

GO:0006357

GO:0010628

GO:0016573

GO:0016922

GO:0019904

GO:0023052

GO:0030374

GO:0030520

GO:0031063

GO:0031647

GO:0033276

GO:0035521

GO:0035522

GO:0036211

GO:0043226

GO:0043229

GO:0043484

GO:0043966

GO:0044154

GO:0045893

GO:0045995

GO:0048856

GO:0051302

GO:0051726

GO:0072686

GO:0090043

GO:0140110

GO:0140672

HMNXSV003025515

HMNXSV003033240

Hs.158196.3.S1_3p_a_at

ILMN_1674866

ILMN_1770141

ILMN_1792176

PH_hs_0024391

TC03001150.hg

g5911971_3p_at

g5911971_3p_x_at

Participates

as a component of

as an input of

Inferred To

Tada3 [nucleoplasm] (Mus musculus)

Tada3 [nucleoplasm] (Rattus norvegicus)

TADA3 [nucleoplasm] (Bos taurus)

TADA3 [nucleoplasm] (Canis familiaris)

TADA3 [nucleoplasm] (Dictyostelium discoideum)

TADA3 [nucleoplasm] (Gallus gallus)

TADA3 [nucleoplasm] (Sus scrofa)

ngg1 [nucleoplasm] (Schizosaccharomyces pombe)

tada3 [nucleoplasm] (Danio rerio)

Ada3 [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of TADA3 [nucleoplasm] (Xenopus tropicalis)

NGG1 [nucleoplasm] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_597814.1, NP_006345.1, NP_001265199.1

OpenTargets

ENSG00000171148

HPA

ENSG00000171148-TADA3

GeneCards

O75528

Ensembl

ENSP00000343649, ENSP00000307684, ENST00000440161, ENSG00000171148, ENSP00000393471, ENST00000301964, ENST00000343450

PRO

O75528

Pharos - Targets

O75528

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96ES7 SGF29	1	SGF29 [nucleoplasm] (R-HSA-3662279)	0.905	12
UniProt:P61964 WDR5	1	WDR5 [nucleoplasm] (R-HSA-1629838)	0.643	3
UniProt:Q92831 KAT2B	1	KAT2B [nucleoplasm] (R-HSA-352430)	0.643	3
UniProt:Q96MH2 HEXI2			0.556	3
UniProt:Q7Z699 SPRED1	2	SPRED1 [plasma membrane] (R-HSA-5658225) SPRED1 [cytosol] (R-HSA-5654207)	0.556	3
UniProt:Q8N3L3 TXLNB			0.556	3
UniProt:P28702-3 RXRB			0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:Q9BVL2 NUP58			0.556	3
UniProt:Q9UMF0 ICAM5	1	ICAM5 [plasma membrane] (R-HSA-197684)	0.556	3
UniProt:P28329-3 P283293			0.556	3
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.556	3
UniProt:P01112 HRAS	20	HRAS Q61R [plasma membrane] (R-HSA-6802458) HRAS Q61L [plasma membrane] (R-HSA-6802452) HRAS Q61K [plasma membrane] (R-HSA-6802442) HRAS G13R [plasma membrane] (R-HSA-6802368) HRAS G12V [plasma membrane] (R-HSA-6802350) HRAS G12S [plasma membrane] (R-HSA-6802343) HRAS T58I [plasma membrane] (R-HSA-9656014) HRAS G13C [plasma membrane] (R-HSA-9656008) HRAS K117R [plasma membrane] (R-HSA-9656010) HRAS G13V [plasma membrane] (R-HSA-9656579) HRAS G13D [plasma membrane] (R-HSA-9656572) HRAS G13S [plasma membrane] (R-HSA-9656574) HRAS K117N [plasma membrane] (R-HSA-9656603) HRAS G12D [plasma membrane] (R-HSA-9656564) HRAS G12C [plasma membrane] (R-HSA-9656561) S-Farn-Me HRAS [plasma membrane] (R-HSA-9665052) HRAS [plasma membrane] (R-HSA-62717) S-Farn-Me PalmS HRAS [Golgi membrane] (R-HSA-9647896) S-Farn-Me HRAS [endoplasmic reticulum membrane] (R-HSA-9647796) S-Farn-HRAS [endoplasmic reticulum membrane] (R-HSA-9647788)	0.556	3
UniProt:O75558 STX11			0.556	3
UniProt:Q8N2N9-4 ANKRD36B			0.556	3
UniProt:O75478 TADA2A	1	TADA2A [nucleoplasm] (R-HSA-3662284)	0.547	2
UniProt:Q92830 KAT2A	1	KAT2A [nucleoplasm] (R-HSA-3006516)	0.527	2
UniProt:Q8N2W9 PIAS4	2	PIAS4 [nucleoplasm] (R-HSA-2993789) monoSUMO1-K35-PIAS4 [nucleoplasm] (R-HSA-3968415)	0.508	2
UniProt:P45974 USP5	1	USP5 [cytosol] (R-HSA-5690104)	0.508	2
UniProt:Q9NY61 AATF	1	AATF [cytosol] (R-HSA-205071)	0.508	2
UniProt:P06930 VE6			0.488	2

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