PRDX6:GSTP1 catalyzes 2 glutathione, reduced + H2O2 => glutathione, oxidized + 2 H2O

Stable Identifier
R-HSA-3343700
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Peroxiredoxin 6 (PRDX6) forms a heterodimer with GSTP1 (Pi Glutathione transferase) and catalyzes the reduction of hydrogen peroxide (H2O2) by glutathione to yield oxidized glutathione and water (Ralat et al. 2006, Ralat et al. 2008, Zhou et al. 2013).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
glutathione peroxidase activity of PRDX6:GSTP1 [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea