Regulation of HSF1-mediated heat shock response

Stable Identifier
R-HSA-3371453
Type
Pathway
Species
Homo sapiens
Locations in the PathwayBrowser
Expand all
Summation

The ability of HSF1 to respond to cellular stresses is under negative regulation by chaperones, modulation of nucleocytoplasmic shuttling, post-translational modifications and transition from monomeric to trimeric state.

Literature References
PubMed ID Title Journal Year
7623826 Multiple layers of regulation of human heat shock transcription factor 1

Zuo, J, Rungger, D, Voellmy, R

Mol. Cell. Biol. 1995
Participants
Events
Participant Of
hasEvent
Event Information
Go Biological Process
regulation of cellular response to heat (1900034)
Orthologous Events
Regulation of HSF1-mediated heat shock response (Arabidopsis thaliana)
Regulation of HSF1-mediated heat shock response (Bos taurus)
Regulation of HSF1-mediated heat shock response (Caenorhabditis elegans)
Regulation of HSF1-mediated heat shock response (Canis familiaris)
Regulation of HSF1-mediated heat shock response (Danio rerio)
Regulation of HSF1-mediated heat shock response (Dictyostelium discoideum)
Regulation of HSF1-mediated heat shock response (Drosophila melanogaster)
Regulation of HSF1-mediated heat shock response (Gallus gallus)
Regulation of HSF1-mediated heat shock response (Mus musculus)
Regulation of HSF1-mediated heat shock response (Oryza sativa)
Regulation of HSF1-mediated heat shock response (Plasmodium falciparum)
Regulation of HSF1-mediated heat shock response (Rattus norvegicus)
Regulation of HSF1-mediated heat shock response (Saccharomyces cerevisiae)
Regulation of HSF1-mediated heat shock response (Schizosaccharomyces pombe)
Regulation of HSF1-mediated heat shock response (Sus scrofa)
Regulation of HSF1-mediated heat shock response (Taeniopygia guttata)
Regulation of HSF1-mediated heat shock response (Xenopus tropicalis)
Authored
Shamovsky, V  (2013-10-29)
Reviewed
Pani, B  (2014-02-17)