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Interaction of integrin alphaIIbbeta3 with Fibronectin
Stable Identifier
R-HSA-349593
Type
Reaction [binding]
Species
Homo sapiens
Compartment
extracellular region
,
plasma membrane
ReviewStatus
5/5
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Extracellular matrix organization (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
Interaction of integrin alphaIIbbeta3 with Fibronectin (Homo sapiens)
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Fibronectin plays a role in cell adhesion and cell migration. It mediates platelet adhesion in the vasculature by interacting with integrin alphaIIbbeta3.
Literature References
PubMed ID
Title
Journal
Year
16933105
The synergy site of fibronectin is required for strong interaction with the platelet integrin alphaIIbbeta3
Mather, T
,
Nollert, MU
,
Chada, D
Ann Biomed Eng
2006
Participants
Input
FN1(32-2386) [extracellular region]
(Homo sapiens)
Integrin alphaIIb:beta3 [plasma membrane]
(Homo sapiens)
Output
Integrin alpha2bbeta3:FN1(32-2386) [plasma membrane]
(Homo sapiens)
Participates
as an event of
Integrin cell surface interactions (Homo sapiens)
Orthologous Events
Interaction of integrin alphaIIbbeta3 with Fibronectin (Bos taurus)
Interaction of integrin alphaIIbbeta3 with Fibronectin (Caenorhabditis elegans)
Interaction of integrin alphaIIbbeta3 with Fibronectin (Canis familiaris)
Interaction of integrin alphaIIbbeta3 with Fibronectin (Gallus gallus)
Interaction of integrin alphaIIbbeta3 with Fibronectin (Mus musculus)
Interaction of integrin alphaIIbbeta3 with Fibronectin (Rattus norvegicus)
Interaction of integrin alphaIIbbeta3 with Fibronectin (Sus scrofa)
Interaction of integrin alphaIIbbeta3 with Fibronectin (Xenopus tropicalis)
Authored
Geiger, B (2008-05-07)
Horwitz, AR (2008-05-07)
Reviewed
Humphries, MJ (2008-05-07)
Yamada, KM (2008-05-07)
Hynes, R (2008-05-07)
Created
Garapati, P V (2008-05-12)
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