Reactome | ALDOA [platelet alpha granule lumen]

ALDOA [platelet alpha granule lumen]

Stable Identifier

R-HSA-349738

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

platelet alpha granule lumen

Synonyms

Fructose-bisphosphate aldolase A , Muscle-type aldolase, Lung cancer antigen NY-LU-1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P04075 ALDOA

Gene Names

ALDOA, ALDA

Chain

initiator methionine:, chain:2-364

Reference Genes

COSMIC (genes):ALDOA ALDOA

dbSNP Gene:226 ALDOA

ENSEMBL:ENSG00000149925 ALDOA

Participates

as a member of

Platelet alpha granule contents [platelet alpha granule lumen] (Homo sapiens)

Other forms of this molecule

ALDOA [ficolin-1-rich granule lumen]

ALDOA [tertiary granule lumen]

ALDOA [extracellular region]

ALDOA [secretory granule lumen]

ALDOA [cytosol]

Inferred To

Ald2 [platelet alpha granule lumen] (Drosophila melanogaster)

ALDOA [platelet alpha granule lumen] (Bos taurus)

ALDOA [platelet alpha granule lumen] (Caenorhabditis elegans)

ALDOA [platelet alpha granule lumen] (Canis familiaris)

ALDOA [platelet alpha granule lumen] (Dictyostelium discoideum)

ALDOA [platelet alpha granule lumen] (Drosophila melanogaster)

ALDOA [platelet alpha granule lumen] (Mus musculus)

ALDOA [platelet alpha granule lumen] (Plasmodium falciparum)

ALDOA [platelet alpha granule lumen] (Rattus norvegicus)

ALDOA [platelet alpha granule lumen] (Sus scrofa)

Homologues of ALDOA [platelet alpha granule lumen] (Caenorhabditis elegans)

Homologues of ALDOA [platelet alpha granule lumen] (Drosophila melanogaster)

aldoa [platelet alpha granule lumen] (Xenopus tropicalis)

aldoaa [platelet alpha granule lumen] (Danio rerio)

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.706	18
UniProt:P12004 PCNA	5	PCNA [nucleoplasm] (R-HSA-68439) MonoUb-K164-PCNA [nucleoplasm] (R-HSA-5651986) ISG-K164,ISG-K168-PCNA [nucleoplasm] (R-HSA-5653768) K63polyUb-K164-PCNA [nucleoplasm] (R-HSA-8943000) monoSUMO1-K164,K254,K-PCNA [nucleoplasm] (R-HSA-4615861)	0.571	3
UniProt:P10636-8 MAPT	3	MAPT-8 [cytosol] (R-HSA-9619519) p-S262,S356,S396-MAPT-8 [cytosol] (R-HSA-9619521) p-S199,S202,S262,S396,S404,S409,T181,T231-MAPT-8 [cytosol] (R-HSA-9836400)	0.569	10
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:Q86X55 CARM1	1	CARM1 [nucleoplasm] (R-HSA-400139)	0.499	2