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CALU [extracellular region]
Stable Identifier
R-HSA-350739
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Calumenin
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Platelet activation, signaling and aggregation (Homo sapiens)
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Platelet degranulation (Homo sapiens)
Release of Calumenin (Homo sapiens)
CALU [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:O43852 CALU
Gene Names
CALU
Chain
signal peptide:1-19, chain:20-315
Reference Genes
BioGPS Gene:813 CALU
COSMIC (genes):CALU CALU
CTD Gene:813 CALU
dbSNP Gene:813 CALU
ENSEMBL:ENSG00000128595 CALU
HGNC:1458 CALU
KEGG Gene (Homo sapiens):813 CALU
Monarch:813 CALU
NCBI Gene:813 CALU
OMIM:603420 CALU
UCSC:O43852 CALU
Reference Transcript
RefSeq:XM_017012659.1 CALU
RefSeq:NM_001199673.1 CALU
RefSeq:NM_001199671.1 CALU
RefSeq:NM_001219.4 CALU
RefSeq:NM_001130674.2 CALU
RefSeq:NM_001199672.1 CALU
Other Identifiers
0000460372
11725306_s_at
11725307_s_at
11725308_a_at
17051236
200755_s_at
200756_x_at
200757_s_at
214845_s_at
229549_at
3023061
3023067
3023068
3023070
3023073
3023075
3023078
3023079
3023082
3023084
3023085
3023086
3023087
3023088
3023089
3023090
3023091
3023092
3023094
37345_at
52813_at
813
8135955
83794_at
A_14_P127960
A_23_P122815
GE58250
GE83826
GE86010
GO:0003674
GO:0005509
GO:0005515
GO:0005575
GO:0005576
GO:0005622
GO:0005737
GO:0005783
GO:0005788
GO:0005789
GO:0005794
GO:0006464
GO:0008150
GO:0016020
GO:0016529
GO:0031410
GO:0033018
GO:0042470
GO:0043167
GO:0043226
GO:0043687
GO:0044267
GO:0046872
Hs.302073.0.S1_3p_s_at
Hs.7753.0.S2_3p_a_at
Hs.7753.0.S2_3p_s_at
Hs.7753.2.S1_3p_at
ILMN_1727194
PH_hs_0000799
PH_hs_0039542
TC07000782.hg
TC07002576.hg
g6005991_3p_a_at
Participant Of
output
Release of Calumenin
Other forms of this molecule
CALU [endoplasmic reticulum lumen]
p-CALU [endoplasmic reticulum lumen]
Cross References
RefSeq
NP_001210.1
,
NP_001186600.1
,
NP_001124146.1
,
NP_001186602.1
,
XP_016868148.1
,
NP_001186601.1
Target Pathogen
5b354852be737e166372ea83
OpenTargets
ENSG00000128595
GeneCards
O43852
HPA
ENSG00000128595-CALU
Ensembl
ENST00000249364
,
ENSG00000128595
,
ENSP00000249364
,
ENSP00000420381
,
ENSP00000442110
,
ENST00000479257
,
ENSP00000438248
,
ENST00000535011
,
ENST00000542996
,
ENST00000449187
,
ENSP00000408838
PRO
O43852
Orphanet
24387
HMDB Protein
HMDBP07534
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P04049 RAF1
54
p-S338,Y340,Y341-RAF1 [cytosol]
(R-HSA-5624465)
RAF1 [cytosol]
(R-HSA-167205)
p-S338-RAF1 [cytosol]
(R-HSA-5624469)
p-S621-RAF1 S259F [cytosol]
(R-HSA-9656124)
p-S621-RAF1 S257L [cytosol]
(R-HSA-9656121)
p-S621-RAF1 P261L [cytosol]
(R-HSA-9656106)
p-S621-RAF1 N262K [cytosol]
(R-HSA-9656101)
p-S621-RAF1 P261A [cytosol]
(R-HSA-9656103)
p-S621-RAF1 P261S [cytosol]
(R-HSA-9656113)
p-S621-RAF1 S259T [cytosol]
(R-HSA-9656130)
p-S621-RAF1 P261T [cytosol]
(R-HSA-9656115)
p-S621-RAF1 P261R [cytosol]
(R-HSA-9656110)
p-S621-RAF1 S259P [cytosol]
(R-HSA-9656127)
p-S621-RAF1 T260I [cytosol]
(R-HSA-9656136)
p-S621-RAF1 T260R [cytosol]
(R-HSA-9656139)
p-S621-RAF1 V263A [cytosol]
(R-HSA-9656148)
p-S621-RAF1 R256S [cytosol]
(R-HSA-9656119)
p-S621-RAF1 T491I [cytosol]
(R-HSA-9656143)
p-S621-RAF1 D486N [cytosol]
(R-HSA-9656088)
p-S621-RAF1 S427G [cytosol]
(R-HSA-9656134)
p-S621-RAF1 L613V [cytosol]
(R-HSA-9656098)
p-S621-RAF1 G361A [cytosol]
(R-HSA-9656092)
p-S621-RAF1 G370R [cytosol]
(R-HSA-9656094)
p-S621-RAF1 D486G [cytosol]
(R-HSA-9656085)
p-S621-RAF1 T491R [cytosol]
(R-HSA-9656145)
p-S338,Y341,T492,S494,S621 RAF1 D486N [cytosol]
(R-HSA-9656026)
p-S338,Y341,T492,S494,S621 RAF1 S427G [cytosol]
(R-HSA-9656070)
p-S338,Y341,T492,S494,S621 RAF1 L613V [cytosol]
(R-HSA-9656035)
p-S338,Y341,S494,S621-RAF1 T491I [cytosol]
(R-HSA-9656019)
p-S338,Y341,T492,S494,S621 RAF1 G361A [cytosol]
(R-HSA-9656029)
p-S338,Y341,T492,S494,S621 RAF1 G370R [cytosol]
(R-HSA-9656031)
p-S338,Y341,T492,S494,S621 RAF1 D486G [cytosol]
(R-HSA-9656023)
p-S338,Y341,S494,S621 RAF1 T491R [cytosol]
(R-HSA-9656017)
p-S338,Y341,T492,S494,S621 RAF1 S259F [cytosol]
(R-HSA-9656062)
p-S338,Y341,T492,S494,S621 RAF1 P261A [cytosol]
(R-HSA-9656041)
p-S338,Y341,T492,S494,S621 RAF1 S257L [cytosol]
(R-HSA-9656058)
p-S338,Y341,T492,S494,S621 RAF1 P261L [cytosol]
(R-HSA-9656043)
p-S338,Y341,T492,S494,S621 RAF1 P261T [cytosol]
(R-HSA-9656053)
p-S338,Y341,T492,S494,S621 RAF1 N262K [cytosol]
(R-HSA-9656037)
p-S338,Y341,T492,S494,S621 RAF1 P261S [cytosol]
(R-HSA-9656050)
p-S338,Y341,T492,S494,S621 RAF1 S259T [cytosol]
(R-HSA-9656067)
p-S338,Y341,T492,S494,S621 RAF1 T260R [cytosol]
(R-HSA-9656077)
p-S338,Y341,T492,S494,S621 RAF1 P261R [cytosol]
(R-HSA-9656047)
p-S338,Y341,T492,S494,S621 RAF1 R256S [cytosol]
(R-HSA-9656056)
p-S338,Y341,T492,S494,S621 RAF1 T260I [cytosol]
(R-HSA-9656074)
p-S338,Y341,T492,S494,S621 RAF1 V263A [cytosol]
(R-HSA-9656080)
p-S338,Y341,T492,S494,S621 RAF1 S259P [cytosol]
(R-HSA-9656065)
hyperphosphorylated RAF1 [plasma membrane]
(R-HSA-5675193)
p-S621-RAF1 [plasma membrane]
(R-HSA-206222)
p-Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-HSA-5675420)
p-S259,S621-RAF1 [cytosol]
(R-HSA-109786)
p-S621-RAF1 [cytosol]
(R-HSA-206028)
p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane]
(R-HSA-5672665)
p-S338,Y341,T491,S494,S621 RAF1 [cytosol]
(R-HSA-5672664)
0.643
4
UniProt:Q9UMX0-2 UBQLN1
0.556
3
UniProt:P0DTC5 M
8
N-glycan M [endocytic vesicle membrane]
(R-COV-9694738)
M [endocytic vesicle membrane]
(R-COV-9694563)
N-glycan M [endoplasmic reticulum membrane]
(R-COV-9694684)
nascent M [endoplasmic reticulum lumen]
(R-COV-9694279)
N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694446)
M [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9694439)
M [virion membrane]
(R-COV-9694320)
N-glycan M [virion membrane]
(R-COV-9694385)
0.527
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.527
2
UniProt:Q12824 SMARCB1
1
SMARCB1 [nucleoplasm]
(R-HSA-389261)
0.462
4
UniProt:Q9Y2H1 ST38L
0.462
4
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