Reactome | CALU [extracellular region]

CALU [extracellular region]

Stable Identifier

R-HSA-350739

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

Calumenin

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:O43852 CALU

Gene Names

CALU

Chain

signal peptide:1-19, chain:20-315

Reference Genes

BioGPS Gene:813 CALU

COSMIC (genes):CALU CALU

CTD Gene:813 CALU

dbSNP Gene:813 CALU

ENSEMBL:ENSG00000128595 CALU

HGNC:1458 CALU

KEGG Gene (Homo sapiens):813 CALU

Monarch:813 CALU

NCBI Gene:813 CALU

OMIM:603420 CALU

UCSC:O43852 CALU

Reference Transcript

Other Identifiers

0000460372

11725306_s_at

11725307_s_at

11725308_a_at

17051236

200755_s_at

200756_x_at

200757_s_at

214845_s_at

229549_at

3023061

3023067

3023068

3023070

3023073

3023075

3023078

3023079

3023082

3023084

3023085

3023086

3023087

3023088

3023089

3023090

3023091

3023092

3023094

37345_at

52813_at

813

8135955

83794_at

A_14_P127960

A_23_P122815

GE58250

GE83826

GE86010

GO:0003674

GO:0005509

GO:0005515

GO:0005575

GO:0005576

GO:0005622

GO:0005737

GO:0005783

GO:0005788

GO:0005789

GO:0005794

GO:0006464

GO:0008150

GO:0016020

GO:0016529

GO:0031410

GO:0033018

GO:0042470

GO:0043167

GO:0043226

GO:0043687

GO:0044267

GO:0046872

Hs.302073.0.S1_3p_s_at

Hs.7753.0.S2_3p_a_at

Hs.7753.0.S2_3p_s_at

Hs.7753.2.S1_3p_at

ILMN_1727194

PH_hs_0000799

PH_hs_0039542

TC07000782.hg

TC07002576.hg

g6005991_3p_a_at

Participant Of

output

Release of Calumenin

Other forms of this molecule

CALU [endoplasmic reticulum lumen]

p-CALU [endoplasmic reticulum lumen]

Cross References

RefSeq

NP_001210.1, NP_001186600.1, NP_001124146.1, NP_001186602.1, XP_016868148.1, NP_001186601.1

Target Pathogen

5b354852be737e166372ea83

OpenTargets

ENSG00000128595

GeneCards

O43852

HPA

ENSG00000128595-CALU

Ensembl

ENST00000249364, ENSG00000128595, ENSP00000249364, ENSP00000420381, ENSP00000442110, ENST00000479257, ENSP00000438248, ENST00000535011, ENST00000542996, ENST00000449187, ENSP00000408838

PRO

O43852

Orphanet

24387

HMDB Protein

HMDBP07534

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04049 RAF1	54	p-S338,Y340,Y341-RAF1 [cytosol] (R-HSA-5624465) RAF1 [cytosol] (R-HSA-167205) p-S338-RAF1 [cytosol] (R-HSA-5624469) p-S621-RAF1 S259F [cytosol] (R-HSA-9656124) p-S621-RAF1 S257L [cytosol] (R-HSA-9656121) p-S621-RAF1 P261L [cytosol] (R-HSA-9656106) p-S621-RAF1 N262K [cytosol] (R-HSA-9656101) p-S621-RAF1 P261A [cytosol] (R-HSA-9656103) p-S621-RAF1 P261S [cytosol] (R-HSA-9656113) p-S621-RAF1 S259T [cytosol] (R-HSA-9656130) p-S621-RAF1 P261T [cytosol] (R-HSA-9656115) p-S621-RAF1 P261R [cytosol] (R-HSA-9656110) p-S621-RAF1 S259P [cytosol] (R-HSA-9656127) p-S621-RAF1 T260I [cytosol] (R-HSA-9656136) p-S621-RAF1 T260R [cytosol] (R-HSA-9656139) p-S621-RAF1 V263A [cytosol] (R-HSA-9656148) p-S621-RAF1 R256S [cytosol] (R-HSA-9656119) p-S621-RAF1 T491I [cytosol] (R-HSA-9656143) p-S621-RAF1 D486N [cytosol] (R-HSA-9656088) p-S621-RAF1 S427G [cytosol] (R-HSA-9656134) p-S621-RAF1 L613V [cytosol] (R-HSA-9656098) p-S621-RAF1 G361A [cytosol] (R-HSA-9656092) p-S621-RAF1 G370R [cytosol] (R-HSA-9656094) p-S621-RAF1 D486G [cytosol] (R-HSA-9656085) p-S621-RAF1 T491R [cytosol] (R-HSA-9656145) p-S338,Y341,T492,S494,S621 RAF1 D486N [cytosol] (R-HSA-9656026) p-S338,Y341,T492,S494,S621 RAF1 S427G [cytosol] (R-HSA-9656070) p-S338,Y341,T492,S494,S621 RAF1 L613V [cytosol] (R-HSA-9656035) p-S338,Y341,S494,S621-RAF1 T491I [cytosol] (R-HSA-9656019) p-S338,Y341,T492,S494,S621 RAF1 G361A [cytosol] (R-HSA-9656029) p-S338,Y341,T492,S494,S621 RAF1 G370R [cytosol] (R-HSA-9656031) p-S338,Y341,T492,S494,S621 RAF1 D486G [cytosol] (R-HSA-9656023) p-S338,Y341,S494,S621 RAF1 T491R [cytosol] (R-HSA-9656017) p-S338,Y341,T492,S494,S621 RAF1 S259F [cytosol] (R-HSA-9656062) p-S338,Y341,T492,S494,S621 RAF1 P261A [cytosol] (R-HSA-9656041) p-S338,Y341,T492,S494,S621 RAF1 S257L [cytosol] (R-HSA-9656058) p-S338,Y341,T492,S494,S621 RAF1 P261L [cytosol] (R-HSA-9656043) p-S338,Y341,T492,S494,S621 RAF1 P261T [cytosol] (R-HSA-9656053) p-S338,Y341,T492,S494,S621 RAF1 N262K [cytosol] (R-HSA-9656037) p-S338,Y341,T492,S494,S621 RAF1 P261S [cytosol] (R-HSA-9656050) p-S338,Y341,T492,S494,S621 RAF1 S259T [cytosol] (R-HSA-9656067) p-S338,Y341,T492,S494,S621 RAF1 T260R [cytosol] (R-HSA-9656077) p-S338,Y341,T492,S494,S621 RAF1 P261R [cytosol] (R-HSA-9656047) p-S338,Y341,T492,S494,S621 RAF1 R256S [cytosol] (R-HSA-9656056) p-S338,Y341,T492,S494,S621 RAF1 T260I [cytosol] (R-HSA-9656074) p-S338,Y341,T492,S494,S621 RAF1 V263A [cytosol] (R-HSA-9656080) p-S338,Y341,T492,S494,S621 RAF1 S259P [cytosol] (R-HSA-9656065) hyperphosphorylated RAF1 [plasma membrane] (R-HSA-5675193) p-S621-RAF1 [plasma membrane] (R-HSA-206222) p-Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5675420) p-S259,S621-RAF1 [cytosol] (R-HSA-109786) p-S621-RAF1 [cytosol] (R-HSA-206028) p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5672665) p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (R-HSA-5672664)	0.643	4
UniProt:Q9UMX0-2 UBQLN1			0.556	3
UniProt:P0DTC5 M	8	N-glycan M [endocytic vesicle membrane] (R-COV-9694738) M [endocytic vesicle membrane] (R-COV-9694563) N-glycan M [endoplasmic reticulum membrane] (R-COV-9694684) nascent M [endoplasmic reticulum lumen] (R-COV-9694279) N-glycan M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694446) M [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9694439) M [virion membrane] (R-COV-9694320) N-glycan M [virion membrane] (R-COV-9694385)	0.527	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.527	2
UniProt:Q12824 SMARCB1	1	SMARCB1 [nucleoplasm] (R-HSA-389261)	0.462	4
UniProt:Q9Y2H1 ST38L			0.462	4

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