Reactome | DAAM1 [cytosol]

DAAM1 [cytosol]

Stable Identifier

R-HSA-351052

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Daam1

Icon

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y4D1 DAAM1

Gene Names

DAAM1, KIAA0666

Chain

chain:1-1078

Reference Genes

BioGPS Gene:23002 DAAM1

COSMIC (genes):DAAM1 DAAM1

CTD Gene:23002 DAAM1

dbSNP Gene:23002 DAAM1

ENSEMBL:ENSG00000100592 DAAM1

ENSEMBL_homo_sapiens_GENE:ENSG00000100592.16 DAAM1

HGNC:18142 DAAM1

KEGG Gene (Homo sapiens):23002 DAAM1

Monarch:23002 DAAM1

NCBI Gene:23002 DAAM1

OMIM:606626 DAAM1

UCSC:Q9Y4D1 DAAM1

Reference Transcript

Other Identifiers

11755080_a_at

16784787

216060_PM_s_at

216060_s_at

226666_PM_at

226666_at

23002

33753_at

3538214

3538226

3538227

3538233

3538241

3538243

3538245

3538246

3538247

3538248

3538249

3538250

3538251

3538252

3538254

3538255

3538256

3538257

3538258

3538259

3538263

3538266

3538269

3538270

3538272

3538273

3538274

3538275

3538285

3538288

3538292

3538295

3538296

3538297

3538298

49389_at

7974697

A_14_P126161

A_14_P126298

A_14_P137201

A_23_P54116

A_24_P347447

GE79693

GE85996

GO:0001725

GO:0003779

GO:0005515

GO:0005737

GO:0005815

GO:0005829

GO:0005856

GO:0005886

GO:0005929

GO:0007010

GO:0008092

GO:0016020

GO:0016043

GO:0016055

GO:0023052

GO:0030036

GO:0031267

GO:0031514

GO:0036064

GO:0042802

GO:0042995

GO:0043226

GO:0048471

GO:0048856

GO:0060071

HMNXSV003047685

Hs.197751.0.A1_3p_at

Hs.197751.2.S1_3p_a_at

ILMN_1787251

ILMN_2046470

PH_hs_0024003

TC14000356.hg

TC14001714.hg

Participates

as a component of

as an input of

as a member of

as a candidate of

CDC42 effectors [cytosol] (Homo sapiens)

Inferred To

forD [cytosol] (Dictyostelium discoideum)

forF [cytosol] (Dictyostelium discoideum)

Homologues of DAAM1 [cytosol] (Dictyostelium discoideum)

Daam1 [cytosol] (Mus musculus)

Daam1 [cytosol] (Rattus norvegicus)

forE [cytosol] (Dictyostelium discoideum)

forH [cytosol] (Dictyostelium discoideum)

forA [cytosol] (Dictyostelium discoideum)

daam1b [cytosol] (Danio rerio)

daam-1 [cytosol] (Caenorhabditis elegans)

daam1 [cytosol] (Xenopus tropicalis)

DAAM [cytosol] (Drosophila melanogaster)

forB [cytosol] (Dictyostelium discoideum)

DAAM1 [cytosol] (Bos taurus)

DAAM1 [cytosol] (Canis familiaris)

DAAM1 [cytosol] (Gallus gallus)

DAAM1 [cytosol] (Plasmodium falciparum)

DAAM1 [cytosol] (Sus scrofa)

Cross References

RefSeq

XP_005267487.1, NP_055807.1, NP_001257449.1, XP_005267488.1

OpenTargets

ENSG00000100592

HPA

ENSG00000100592-DAAM1

GeneCards

Q9Y4D1

Ensembl

ENST00000395125, ENSP00000378557, ENSP00000354162, ENSG00000100592, ENST00000360909

PRO

Q9Y4D1

Pharos - Targets

Q9Y4D1

HMDB Protein

HMDBP08342

PDB

2Z6E, 2J1D

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61586 RHOA	6	RHOA [ficolin-1-rich granule membrane] (R-HSA-6804971) RHOA [secretory granule membrane] (R-HSA-6804980) RHOA [endoplasmic reticulum membrane] (R-HSA-5672082) RHOA [cytosol] (R-HSA-194866) RHOA [cell junction] (R-HSA-2134503) RHOA [plasma membrane] (R-HSA-194510)	0.831	10
UniProt:Q9Y4D1 DAAM1	1	DAAM1 [cytosol] (R-HSA-351052)	0.609	2
UniProt:P08134 RHOC	3	RHOC [plasma membrane] (R-HSA-194870) RHOC [cytosol] (R-HSA-194853) RHOC [endoplasmic reticulum membrane] (R-HSA-9714362)	0.59	3
UniProt:O00212 RHOD	5	RHOD [mitochondrial outer membrane] (R-HSA-9693212) RHOD [cytosol] (R-HSA-194848) RHOD [plasma membrane] (R-HSA-194889) RHOD [Golgi membrane] (R-HSA-9693236) RHOD [endosome membrane] (R-HSA-5666090)	0.59	3
UniProt:P00523 SRC	9	SRC [cytosol] (R-GGA-9628701) phospho-p-Y419-SRC [cytosol] (R-GGA-8964276) Src [cytosol] (R-GGA-3928468) MyrG-SRC [plasma membrane] (R-GGA-8876922) phospho-p-Y419-SRC [cytosol] (R-GGA-377592) phospho-MyrG,p-Y530-SRC [plasma membrane] (R-GGA-377598) SRC-1 [plasma membrane] (R-GGA-65043) phospho-MyrG-p-Y419-SRC [plasma membrane] (R-GGA-1810408) SRC-2 [cytosol] (R-GGA-191648)	0.556	3
UniProt:Q15642-2 TRIP10			0.524	2
UniProt:Q5T0N5 FNBP1L	1	FNBP1L [cytosol] (R-HSA-8867730)	0.524	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	9
UniProt:O14640 DVL1	4	DVL1 [cytosol] (R-HSA-201687) p-S-DVL1 [cytosol] (R-HSA-201700) pp-DVL1 [cytosol] (R-HSA-3772396) ub-DVL1 [cytosol] (R-HSA-4641157)	0.463	2

Cite Us!