Reactome | DAAM1 [cytosol]

DAAM1 [cytosol]

Stable Identifier

R-HSA-351052

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Daam1

Icon

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y4D1 DAAM1

Gene Names

DAAM1, KIAA0666

Chain

chain:1-1078

Reference Genes

BioGPS Gene:23002 DAAM1

COSMIC (genes):DAAM1 DAAM1

CTD Gene:23002 DAAM1

dbSNP Gene:23002 DAAM1

ENSEMBL:ENSG00000100592 DAAM1

HGNC:18142 DAAM1

KEGG:hsa:23002 DAAM1

Monarch:23002 DAAM1

NCBI Gene:23002 DAAM1

OMIM:606626 DAAM1

UCSC:Q9Y4D1 DAAM1

Reference Transcript

Participates

as a component of

as an input of

as a member of

as a candidate of

CDC42 effectors [cytosol] (Homo sapiens)

Inferred To

forD [cytosol] (Dictyostelium discoideum)

forF [cytosol] (Dictyostelium discoideum)

Homologues of DAAM1 [cytosol] (Dictyostelium discoideum)

Daam1 [cytosol] (Mus musculus)

Daam1 [cytosol] (Rattus norvegicus)

forE [cytosol] (Dictyostelium discoideum)

forH [cytosol] (Dictyostelium discoideum)

forA [cytosol] (Dictyostelium discoideum)

daam1b [cytosol] (Danio rerio)

daam-1 [cytosol] (Caenorhabditis elegans)

daam1 [cytosol] (Xenopus tropicalis)

DAAM [cytosol] (Drosophila melanogaster)

forB [cytosol] (Dictyostelium discoideum)

DAAM1 [cytosol] (Bos taurus)

DAAM1 [cytosol] (Canis familiaris)

DAAM1 [cytosol] (Gallus gallus)

DAAM1 [cytosol] (Plasmodium falciparum)

DAAM1 [cytosol] (Sus scrofa)

Cross References

RefSeq

XP_005267488.1, XP_054231623.1, XP_054231622.1, NP_055807.1, XP_005267487.1, XP_047287091.1, XP_054231621.1, NP_001257449.1

OpenTargets

ENSG00000100592

ENSEMBL

ENSP00000378557, ENSG00000100592, ENST00000395125, ENSP00000354162, ENST00000360909

HPA

ENSG00000100592-DAAM1

GeneCards

DAAM1

PRO

Q9Y4D1

Pharos - Targets

Q9Y4D1

GlyGen

Q9Y4D1

PDB

2J1D, 2Z6E

HMDB Protein

HMDBP08342

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61586 RHOA	6	RHOA [plasma membrane] (R-HSA-194510) RHOA [cell junction] (R-HSA-2134503) RHOA [cytosol] (R-HSA-194866) RHOA [secretory granule membrane] (R-HSA-6804980) RHOA [ficolin-1-rich granule membrane] (R-HSA-6804971) RHOA [endoplasmic reticulum membrane] (R-HSA-5672082)	0.87	11
UniProt:O00212 RHOD	5	RHOD [mitochondrial outer membrane] (R-HSA-9693212) RHOD [cytosol] (R-HSA-194848) RHOD [plasma membrane] (R-HSA-194889) RHOD [Golgi membrane] (R-HSA-9693236) RHOD [endosome membrane] (R-HSA-5666090)	0.688	4
UniProt:P08134 RHOC	3	RHOC [plasma membrane] (R-HSA-194870) RHOC [cytosol] (R-HSA-194853) RHOC [endoplasmic reticulum membrane] (R-HSA-9714362)	0.688	4
UniProt:Q9Y4D1 DAAM1	1	DAAM1 [cytosol] (R-HSA-351052)	0.609	2
UniProt:P00523 SRC	9	SRC [cytosol] (R-GGA-191648) phospho-SRC [plasma membrane] (R-GGA-1810408) SRC [plasma membrane] (R-GGA-65043) phospho-SRC [plasma membrane] (R-GGA-377598) phospho-SRC [cytosol] (R-GGA-377592) Src [cytosol] (R-GGA-3928468) SRC [plasma membrane] (R-GGA-8876922) SRC [cytosol] (R-GGA-9628701) phospho-SRC [cytosol] (R-GGA-8964276)	0.556	3
UniProt:Q9H425 CA198			0.527	3
UniProt:Q8NCC5 SPX3			0.527	2
UniProt:Q8N461 FBXL16	1	FBXL16 [cytosol] (R-HSA-8862609)	0.527	3
UniProt:Q5T0N5 FNBP1L	1	FNBP1L [cytosol] (R-HSA-8867730)	0.524	2
UniProt:Q15642-2 TRIP10			0.524	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	9
UniProt:O14640 DVL1	4	DVL1 [cytosol] (R-HSA-201687) ub-DVL1 [cytosol] (R-HSA-4641157) pp-DVL1 [cytosol] (R-HSA-3772396) p-S-DVL1 [cytosol] (R-HSA-201700)	0.463	2

Cite Us!