dc-Adenosyl methionine + Spermidine => Spermine + 5'-methylthioadenosine

Stable Identifier
R-HSA-351210
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
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The protein encoded by this gene belongs to the spermidine/spermine synthases family. This gene encodes an ubiquitous enzyme of polyamine metabolism. Defects in SMS are the cause of Snyder-Robinson syndrome (SRS).

Literature References
PubMed ID Title Journal Year
7546290 Molecular cloning of a cDNA encoding human spermine synthase

Korhonen, VP, Halmekytö, M, Kauppinen, L, Myöhänen, S, Wahlfors, J, Keinänen, T, Hyvönen, T, Alhonen, L, Eloranta, T, Jänne, J

DNA Cell Biol 1995
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
spermine synthase activity of SMS [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed