Putrescine + dc-Adenosyl methionine => Spermidine + 5'-methylthioadenosine

Stable Identifier
R-HSA-351215
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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General
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Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.

Literature References
PubMed ID Title Journal Year
2069720 Human spermidine synthase gene: structure and chromosomal localization

Myöhänen, S, Kauppinen, L, Wahlfors, J, Alhonen, L, Jänne, J

DNA Cell Biol 1991
Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
spermidine synthase activity of SRM [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea
Authored
Reviewed