Reactome | AMD1(1-67) [cytosol]

AMD1(1-67) [cytosol]

Stable Identifier

R-HSA-351223

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

AdoMetDC

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P17707 AMD1

Gene Names

AMD1, AMD

Chain

chain:1-67, chain:68-334

Reference Genes

BioGPS Gene:262 AMD1

COSMIC (genes):AMD1 AMD1

CTD Gene:262 AMD1

dbSNP Gene:262 AMD1

ENSEMBL:ENSG00000123505 AMD1

ENSEMBL_homo_sapiens_GENE:ENSG00000123505.19 AMD1

HGNC:457 AMD1

KEGG Gene (Homo sapiens):262 AMD1

Monarch:262 AMD1

NCBI Gene:262 AMD1

OMIM:180980 AMD1

UCSC:P17707 AMD1

Reference Transcript

RefSeq:NM_001634.5 AMD1

Other Identifiers

11717237_s_at

11747828_x_at

11747877_x_at

11748140_s_at

11755126_s_at

11758768_x_at

17011671

201196_PM_s_at

201196_s_at

201197_PM_at

201197_at

262

262_at

263_g_at

2855730

2921300

2921301

2921302

2921303

2921304

2921313

2921315

2921317

2921319

2921320

2921321

2921323

2921324

2921325

2921326

2921327

2921328

2921329

2921330

2921331

2921333

36684_at

36685_at

8121489

A_23_P214121

A_24_P371962

A_33_P3395369

GE61981

GO:0003824

GO:0004014

GO:0005515

GO:0005829

GO:0006595

GO:0006596

GO:0006597

GO:0008295

GO:0016829

GO:0016831

GO:0019810

GO:0042802

HMNXSV003007123

HMNXSV003046568

ILMN_1667994

ILMN_1788462

M21154_at

PH_hs_0022749

PH_hs_0031912

TC06000883.hg

g178517_3p_a_at

g5209326_3p_at

Inferred To

SPE2 [cytosol] (Saccharomyces cerevisiae)

spe2 [cytosol] (Schizosaccharomyces pombe)

amd1 [cytosol] (Dictyostelium discoideum)

amd1 [cytosol] (Xenopus tropicalis)

AMD1 [cytosol] (Canis familiaris)

AMD1 [cytosol] (Sus scrofa)

SamDC [cytosol] (Drosophila melanogaster)

AMD1(1-67) [cytosol] (Bos taurus)

AMD1(1-67) [cytosol] (Danio rerio)

AMD1(1-67) [cytosol] (Gallus gallus)

AMD1(1-67) [cytosol] (Mus musculus)

AMD1(1-67) [cytosol] (Rattus norvegicus)

smd-1 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001625.2

ZINC - World Drugs

DCAM_HUMAN

Guide to Pharmacology - Targets

1269

OpenTargets

ENSG00000123505

ZINC - Substances

DCAM_HUMAN

ZINC target

P17707

ZINC - Biogenic

DCAM_HUMAN

PRO

P17707

PDB

3EP4, 3EP3, 1I7M, 3EP8, 3EP7, 3EP6, 3EP5, 3DZ3, 3H0W, 3EPA, 3DZ2, 3H0V, 1I79, 3EP9, 1I72, 1JEN, 3DZ7, 1MSV, 1I7C, 3DZ6, 1JL0, 3DZ5, 1I7B, 3DZ4, 3EPB

ZINC - Investigational

DCAM_HUMAN

ZINC - Metabolites

DCAM_HUMAN

IntEnz

4.1.1.50

HPA

ENSG00000123505-AMD1

GeneCards

P17707

Ensembl

ENST00000368885, ENSP00000357880, ENSG00000123505

Pharos - Targets

P17707

ZINC - Predictions - Purchasable

DCAM_HUMAN

HMDB Protein

HMDBP00420

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96A98 PTH2	1	PTH2(62-100) [extracellular region] (R-HSA-420572)	0.589	2
UniProt:Q8WY91 THAP4			0.556	3
UniProt:P17707 AMD1	1	AMD1(1-67) [cytosol] (R-HSA-351223)	0.556	3
UniProt:Q969T3 SNX21			0.527	2
UniProt:Q96DB2 HDAC11	1	HDAC11 [nucleoplasm] (R-HSA-351590)	0.527	2
UniProt:Q9UK85 DKKL1			0.527	3
UniProt:O95972 BMP15	2	p-BMP15 [endoplasmic reticulum lumen] (R-HSA-8957002) BMP15 [endoplasmic reticulum lumen] (R-HSA-8956729)	0.527	2
UniProt:Q8IVT2 MISP			0.527	2
UniProt:P51888 PRELP	11	PRELP [lysosomal lumen] (R-HSA-2105006) KS(2)-PRELP [lysosomal lumen] (R-HSA-2046286) KS(2)-PRELP [extracellular region] (R-HSA-2046162) KS(2)-PRELP [Golgi lumen] (R-HSA-2046160) KS(1)-PRELP [Golgi lumen] (R-HSA-2046258) Keratan(4)-PRELP [Golgi lumen] (R-HSA-2046276) Keratan(3)-PRELP [Golgi lumen] (R-HSA-2046159) Keratan(2)-PRELP [Golgi lumen] (R-HSA-2046219) Keratan(1)-PRELP [Golgi lumen] (R-HSA-2046292) Gal-glycan PRELP [Golgi lumen] (R-HSA-2046279) N-glycan PRELP [Golgi lumen] (R-HSA-2046156)	0.527	2
UniProt:O95707 POP4	1	POP4 [nucleoplasm] (R-HSA-5696789)	0.527	2
UniProt:Q9UKT5 FBXO4	1	FBXO4 [cytosol] (R-HSA-391298)	0.527	2
UniProt:Q9Y664 KPTN	1	KPTN [lysosomal membrane] (R-HSA-9638238)	0.527	2
UniProt:Q9Y240 CLC11			0.527	3
UniProt:Q96HB5 CC120			0.527	2
UniProt:P18509 ADCYAP1	4	ADCYAP1(132-158) [extracellular region] (R-HSA-420144) ADCYAP1(82-129) [extracellular region] (R-HSA-420254) ADCYAP1(132-169) [extracellular region] (R-HSA-420282) ADCYAP1(2-742) [Golgi membrane] (R-HSA-187679)	0.527	2
UniProt:P01189 POMC	12	POMC(138-176) [secretory granule lumen] (R-HSA-378965) POMC(1-241) [secretory granule lumen] (R-HSA-378943) POMC(138-176) R236G [extracellular region] (R-HSA-5603387) POMC(138-176) E79* [extracellular region] (R-HSA-5623539) POMC(138-176) K25* [extracellular region] (R-HSA-5623536) POMC(138-176) [cytosol] (R-HSA-1502544) POMC(77-87) [extracellular region] (R-HSA-388618) POMC(217-234) [extracellular region] (R-HSA-388617) POMC(138-150) [extracellular region] (R-HSA-388593) POMC(138-176) [extracellular region] (R-HSA-388607) POMC(237-267) [extracellular region] (R-HSA-167405) POMC(237-241) [extracellular region] (R-HSA-167407)	0.527	2
UniProt:Q9NZD2 GLTP	1	GLTP [cytosol] (R-HSA-5216109)	0.527	2

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