Reactome | BMX(1-242) [cytosol]

BMX(1-242) [cytosol]

Stable Identifier

R-HSA-351899

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Etk fragment (1-242)

Locations in the PathwayBrowser for interactor UniProt:O95376 ARIH2

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External Reference Information

External Reference

UniProt:P51813 BMX

Gene Names

BMX

Chain

chain:1-675

Reference Genes

BioGPS Gene:660 BMX

COSMIC (genes):BMX BMX

CTD Gene:660 BMX

dbSNP Gene:660 BMX

ENSEMBL:ENSG00000102010 BMX

ENSEMBL_homo_sapiens_GENE:ENSG00000102010.15 BMX

HGNC:1079 BMX

KEGG Gene (Homo sapiens):660 BMX

Monarch:660 BMX

NCBI Gene:660 BMX

OMIM:300101 BMX

UCSC:P51813 BMX

Reference Transcript

Other Identifiers

11729289_a_at

17101698

206464_PM_at

206464_at

3969803

3969804

3969810

3969811

3969812

3969815

3969816

3969817

3969818

3969819

3969820

3969822

3969823

3969825

3969826

3969827

3969828

3969829

3969830

3969831

3969832

3969834

3969835

3969837

3969842

3969843

660

8166157

962_at

A_23_P253602

A_24_P263144

GE78980

GO:0000166

GO:0002250

GO:0002376

GO:0003824

GO:0004672

GO:0004713

GO:0004715

GO:0005515

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0005886

GO:0006468

GO:0006629

GO:0006661

GO:0006915

GO:0007155

GO:0007165

GO:0007498

GO:0012501

GO:0016301

GO:0016310

GO:0016740

GO:0023052

GO:0032587

GO:0035556

GO:0036211

GO:0043226

GO:0046777

GO:0046872

GO:0048856

GO:0050853

GO:0140096

HMNXSV003027723

ILMN_1672307

ILMN_1759892

ILMN_1796138

PH_hs_0031113

TC0X000067.hg

X83107_at

g4502434_3p_at

Participates

as an output of

Caspase-mediated cleavage of Etk (Homo sapiens)

Other forms of this molecule

BMX [cytosol]

BMX(243-675) [cytosol]

Inferred To

BMX(1-242) [cytosol] (Bos taurus)

BMX(1-242) [cytosol] (Canis familiaris)

BMX(1-242) [cytosol] (Drosophila melanogaster)

BMX(1-242) [cytosol] (Gallus gallus)

BMX(1-242) [cytosol] (Mus musculus)

BMX(1-242) [cytosol] (Sus scrofa)

Bmx [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_001712.1, NP_975010.1, NP_001307795.1

ZINC - World Drugs

BMX_HUMAN

Guide to Pharmacology - Targets

1942

OpenTargets

ENSG00000102010

ZINC - FDA approved

BMX_HUMAN

ZINC - Substances

BMX_HUMAN

ZINC target

P51813

ZINC - Biogenic

BMX_HUMAN

PRO

P51813

PDB

2YS2, 2EKX, 3SXS, 3SXR, 8X2A, 6I99

ZINC - Investigational

BMX_HUMAN

GeneCards

P51813

HPA

ENSG00000102010-BMX

Ensembl

ENST00000342014, ENST00000348343, ENST00000357607, ENSP00000308774, ENSP00000350224, ENSG00000102010, ENSP00000340082

Pharos - Targets

P51813

ZINC - Predictions - Purchasable

BMX_HUMAN

HMDB Protein

HMDBP01238

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P40763 STAT3	12	Unfolded STAT3 [cytosol] (R-HSA-6813811) p-STAT3 [nucleoplasm] (R-HSA-8983188) p-STAT3 [cytosol] (R-HSA-8982823) AcK685- p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701435) p-Y705,S727-STAT3 [nucleoplasm] (R-HSA-9701429) p-S727-STAT3 [cytosol] (R-HSA-198705) p-Y705,S727-STAT3 [cytosol] (R-HSA-539048) p-Y705-STAT3 [nucleoplasm] (R-HSA-9027589) p-Y705-STAT3 [cytosol] (R-HSA-8983130) STAT3 [cytosol] (R-HSA-539044) p-Y705-STAT3 [cytosol] (R-HSA-914048) p-Y705-STAT3 [nucleoplasm] (R-HSA-1112554)	0.83	8
UniProt:Q9UPU5 USP24	1	USP24 [nucleoplasm] (R-HSA-5697004)	0.643	3
UniProt:Q9BRP1 PDD2L			0.643	3
UniProt:P08238 HSP90AB1	6	HSP90AB1 [secretory granule lumen] (R-HSA-6801477) HSP90AB1 [extracellular region] (R-HSA-6806463) HSP90AB1 [ficolin-1-rich granule lumen] (R-HSA-6801491) HSP90AB1 [cytosol] (R-HSA-419617) HSP90AB1 [nucleoplasm] (R-HSA-5082399) HSP90AB1 [lysosomal lumen] (R-HSA-9622846)	0.564	3
UniProt:Q16825 PTN21			0.556	3
UniProt:Q13490 BIRC2	5	K63polyUb-BIRC2 [cytosol] (R-HSA-5668512) BIRC2(1-372) [cytosol] (R-HSA-202913) BIRC2(373-618) [cytosol] (R-HSA-202931) K48pUb-BIRC2 [cytosol] (R-HSA-5675479) BIRC2 [cytosol] (R-HSA-50847)	0.556	3
UniProt:P11309-2 PIM1			0.537	6
UniProt:Q99627 COPS8	2	COPS8 [cytosol] (R-HSA-416962) COPS8 [nucleoplasm] (R-HSA-5697014)	0.527	2
UniProt:O95376 ARIH2	1	ARIH2 [cytosol] (R-HSA-975987)	0.527	2
UniProt:Q5MNZ6 WDR45B	1	WDR45B [cytosol] (R-HSA-5678303)	0.527	2

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