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Go!
BMX [cytosol]
Stable Identifier
R-HSA-351917
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Etk
Locations in the PathwayBrowser for interactor UniProt:O95376 ARIH2
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
Synthesis of PIPs at the plasma membrane (Homo sapiens)
BMX phosphorylates RUFY1 (Homo sapiens)
BMX [cytosol] (Homo sapiens)
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Apoptotic execution phase (Homo sapiens)
Apoptotic cleavage of cellular proteins (Homo sapiens)
Caspase-mediated cleavage of Etk (Homo sapiens)
BMX [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P51813 BMX
Gene Names
BMX
Chain
chain:1-675
Reference Genes
BioGPS Gene:660 BMX
COSMIC (genes):BMX BMX
CTD Gene:660 BMX
dbSNP Gene:660 BMX
ENSEMBL:ENSG00000102010 BMX
ENSEMBL_homo_sapiens_GENE:ENSG00000102010.15 BMX
HGNC:1079 BMX
KEGG Gene (Homo sapiens):660 BMX
Monarch:660 BMX
NCBI Gene:660 BMX
OMIM:300101 BMX
UCSC:P51813 BMX
Reference Transcript
RefSeq:NM_001721.6 BMX
RefSeq:NM_001320866.1 BMX
RefSeq:NM_203281.2 BMX
Other Identifiers
11729289_a_at
17101698
206464_PM_at
206464_at
3969803
3969804
3969810
3969811
3969812
3969815
3969816
3969817
3969818
3969819
3969820
3969822
3969823
3969825
3969826
3969827
3969828
3969829
3969830
3969831
3969832
3969834
3969835
3969837
3969842
3969843
660
8166157
962_at
A_23_P253602
A_24_P263144
GE78980
GO:0000166
GO:0002250
GO:0002376
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005829
GO:0005886
GO:0006468
GO:0006629
GO:0006661
GO:0006915
GO:0007155
GO:0007165
GO:0007498
GO:0012501
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0032587
GO:0035556
GO:0036211
GO:0043226
GO:0046777
GO:0046872
GO:0048856
GO:0050853
GO:0140096
HMNXSV003027723
ILMN_1672307
ILMN_1759892
ILMN_1796138
PH_hs_0031113
TC0X000067.hg
X83107_at
g4502434_3p_at
Participates
as an input of
Caspase-mediated cleavage of Etk (Homo sapiens)
Other forms of this molecule
BMX(1-242) [cytosol]
BMX(243-675) [cytosol]
Inferred To
BMX [cytosol]
(Bos taurus)
BMX [cytosol]
(Canis familiaris)
BMX [cytosol]
(Drosophila melanogaster)
BMX [cytosol]
(Gallus gallus)
BMX [cytosol]
(Mus musculus)
BMX [cytosol]
(Sus scrofa)
Bmx [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
NP_001712.1
,
NP_975010.1
,
NP_001307795.1
ZINC - World Drugs
BMX_HUMAN
Guide to Pharmacology - Targets
1942
OpenTargets
ENSG00000102010
ZINC - FDA approved
BMX_HUMAN
ZINC - Substances
BMX_HUMAN
ZINC target
P51813
ZINC - Biogenic
BMX_HUMAN
PRO
P51813
PDB
2YS2
,
2EKX
,
3SXS
,
3SXR
,
8X2A
,
6I99
ZINC - Investigational
BMX_HUMAN
GeneCards
P51813
HPA
ENSG00000102010-BMX
Ensembl
ENST00000342014
,
ENST00000348343
,
ENST00000357607
,
ENSP00000308774
,
ENSP00000350224
,
ENSG00000102010
,
ENSP00000340082
Pharos - Targets
P51813
ZINC - Predictions - Purchasable
BMX_HUMAN
HMDB Protein
HMDBP01238
Interactors (10)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P40763 STAT3
12
Unfolded STAT3 [cytosol]
(R-HSA-6813811)
p-STAT3 [nucleoplasm]
(R-HSA-8983188)
p-STAT3 [cytosol]
(R-HSA-8982823)
AcK685- p-Y705,S727-STAT3 [nucleoplasm]
(R-HSA-9701435)
p-Y705,S727-STAT3 [nucleoplasm]
(R-HSA-9701429)
p-S727-STAT3 [cytosol]
(R-HSA-198705)
p-Y705,S727-STAT3 [cytosol]
(R-HSA-539048)
p-Y705-STAT3 [nucleoplasm]
(R-HSA-9027589)
p-Y705-STAT3 [cytosol]
(R-HSA-8983130)
STAT3 [cytosol]
(R-HSA-539044)
p-Y705-STAT3 [cytosol]
(R-HSA-914048)
p-Y705-STAT3 [nucleoplasm]
(R-HSA-1112554)
0.83
8
UniProt:Q9UPU5 USP24
1
USP24 [nucleoplasm]
(R-HSA-5697004)
0.643
3
UniProt:Q9BRP1 PDD2L
0.643
3
UniProt:P08238 HSP90AB1
6
HSP90AB1 [secretory granule lumen]
(R-HSA-6801477)
HSP90AB1 [extracellular region]
(R-HSA-6806463)
HSP90AB1 [ficolin-1-rich granule lumen]
(R-HSA-6801491)
HSP90AB1 [cytosol]
(R-HSA-419617)
HSP90AB1 [nucleoplasm]
(R-HSA-5082399)
HSP90AB1 [lysosomal lumen]
(R-HSA-9622846)
0.564
3
UniProt:Q16825 PTN21
0.556
3
UniProt:Q13490 BIRC2
5
K63polyUb-BIRC2 [cytosol]
(R-HSA-5668512)
BIRC2(1-372) [cytosol]
(R-HSA-202913)
BIRC2(373-618) [cytosol]
(R-HSA-202931)
K48pUb-BIRC2 [cytosol]
(R-HSA-5675479)
BIRC2 [cytosol]
(R-HSA-50847)
0.556
3
UniProt:P11309-2 PIM1
0.537
6
UniProt:Q99627 COPS8
2
COPS8 [cytosol]
(R-HSA-416962)
COPS8 [nucleoplasm]
(R-HSA-5697014)
0.527
2
UniProt:O95376 ARIH2
1
ARIH2 [cytosol]
(R-HSA-975987)
0.527
2
UniProt:Q5MNZ6 WDR45B
1
WDR45B [cytosol]
(R-HSA-5678303)
0.527
2
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